Protein Alignment Nha2 and SLC9A6

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001036002.1
• Gene: SLC9A6 / 10479
• HGNCID: 11079
• Length: 701
• Species: Homo sapiens
• Alignment Length: 496
• Identity: 93/496 - (18%)
• Similarity: 172/496 - (34%)
• Gaps: 105/496 - (21%)

  Fly   235 WLY--IRSHWVNTSELVALLAIFLGLWAMGWVLLPE-----------YSQPPTVIMRIAFLFVGA 286
            ||:  .|:.:::.:.|..:..:.:||.....:.:|.           .|.|.|:::.::..|...
Human    89 WLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEY 153

  Fly   287 QISGIL----------------VTFVHLPDMLGMLFFGVLYANLGLANFEGYQKFELFLREMALI 335
            .:.|.:                |||.  |:    :||.:|                       |.
Human   154 MLKGEISSHELNNVQDNEMLRKVTFD--PE----VFFNIL-----------------------LP 189

  Fly   336 NIMLLAGLGLDGDAFKRLWFMILRLTLLPTIVEVAAIAGLANLTLSMPWLWG-----------IA 389
            .|:..||..|....|.|....||....|.|.:....|..:....:::..:.|           :.
Human   190 PIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLL 254

  Fly   390 LGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVII--------SVI 446
            .|.:::|..|..|:.:..:|:.|     ..::.|::..:..||.|||.:...|:        |..
Human   255 FGAIVSATDPVTVLAIFHELQVD-----VELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHT 314

  Fly   447 FSTTSLTQQVLQGPIGIGIGLVFG-YLYGSMLQYLPSRNATYANGLRFVLTILGGTIAVMGSRVI 510
            |..|::.:.     |||.:|:..| :..|:....:.:....:.....|.|...|....:..|..:
Human   315 FDVTAMFKS-----IGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFL 374

  Fly   511 GYTSAGALGCVTTAFIARIGWRREETRLTPQQLQAQQIASVPKRLDLMWKFLKPVSFALIGKEIN 575
            ...:.|..|.|...|..     ..:...|...|..:......:..:|:....:...|:.:|  :.
Human   375 LAEAWGFTGVVAVLFCG-----ITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMG--LT 432

  Fly   576 FNVLQGHVIG----YGALLVLVGSLFRLAFAYLSTYGGNLSRKERAYITISGFPKATVQAAL-GP 635
            ....|.||..    .||.:.:.  |.|.|..|..:...||.|:.:..   |.|....:.|.| |.
Human   433 LFTFQNHVFNPTFVVGAFVAIF--LGRAANIYPLSLLLNLGRRSKIG---SNFQHMMMFAGLRGA 492

  Fly   636 VALDMARAASVASPEQLALAGNLLIISVLAIIFTAPLGAIL 676
            :|..:|...:.....|:..:..|||:.....:|.....|:|
Human   493 MAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAML 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	83/439 (19%)
SLC9A6	NP_001036002.1	NhaP2	93..583	CDD:330436	91/492 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900