Protein Alignment Nha2 and slc9b2

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001093729.1
• Gene: slc9b2 / 100101762
• XenbaseID: XB-GENE-478907
• Length: 539
• Species: Xenopus tropicalis
• Alignment Length: 441
• Identity: 139/441 - (31%)
• Similarity: 228/441 - (51%)
• Gaps: 23/441 - (5%)

  Fly   258 LWAMGWVLLPEYSQPPTVIMRIAFLFVGAQISGILVTFVH------LPDMLGMLFFGVLYANLGL 316
            :||:.|.:......|...:..|..|...|.:.|.|::.:.      ||.:||||..|.|..|:.:
 Frog   105 IWAVVWSITGPECLPGGNLFGILALLFSAALGGKLISLIKIPSLPPLPPLLGMLLAGFLIRNIPV 169

  Fly   317 A--NFEGYQKFELFLREMALINIMLLAGLGLDGDAFKRLWFMILRLTLLPTIVEVAAIAGLANLT 379
            .  ..:.:.|:...||.:||..|::.||||||..|.::|..:.|||:..|.:||....|.:::..
 Frog   170 ITDQVQIHHKWSAALRNIALAIILVRAGLGLDPKALRKLKAVCLRLSFGPCVVESCTAAVVSHFI 234

  Fly   380 LSMPWLWGIALGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIIS 444
            :..|..||..||.|:.||||.|||..||.|:::..|::.||.||:.|..:.:||:||..|...:.
 Frog   235 MGFPLTWGFMLGFVLGAVSPAVVVPSMLILQKEGFGVDKGIPTLLMAAGSFDDVLAITGFNTCLG 299

  Fly   445 VIFSTTSLTQQVLQGPIGIGIGLVFGYLYGSMLQYLPSRNATYANGLRFVLTILGGTIAVMGSRV 509
            :.||:.|....:::|.:.:.:|:..|.|:|..|.|.||::.....|.|..|.:.....||.||..
 Frog   300 MAFSSGSTLNTIVRGVLEVVVGIAAGLLFGFFLHYFPSKDQENLKGKRSYLILALSVFAVFGSLY 364

  Fly   510 IGYTSAGALGCVTTAFIARIGWRREETRLTPQQLQAQQIASVPKRLDLMWKFLKPVSFALIGKEI 574
            .|:..:|.|..:..||:|.|||..::|       ..:.|.:|      .|...:|:.|.|||.||
 Frog   365 FGFPGSGGLCTLVMAFLAGIGWSTDKT-------VVEDIIAV------SWDIFQPLLFGLIGAEI 416

  Fly   575 NFNVLQGHVIGYGALLVLVGSLFRLAFAYLSTYGGNLSRKERAYITISGFPKATVQAALGPVALD 639
            :...|:...:|.....:::..:.|:..::|.......|.||:.:|:::..||||||||:|.||||
 Frog   417 SVASLKPETVGLCTATLIIALIIRICISFLMVCFSGFSLKEKIFISLAWMPKATVQAAIGSVALD 481

  Fly   640 MARAASVASPEQLALAGNLLIISVLAIIFTAPLGAILMLRLAPYWLKHGDA 690
            .||.......|...:  ::|.::.|.|:.|||:||:::....|..|:..::
 Frog   482 TARTLENKQFEDYGM--DVLTVAFLGILVTAPIGALVIGLTGPKMLEKSES 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	134/414 (32%)
slc9b2	NP_001093729.1	Na_H_Exchanger	121..538	CDD:294713	135/425 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D406317at33208
OrthoFinder	1	1.000	-	-		FOG0001578
OrthoInspector	1	1.000	-	-		mtm9396
Panther	1	1.100	-	-	O	PTHR31102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4408
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.050