DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6660 and CG31523

DIOPT Version :9

Sequence 1:	NP_651104.1	Gene:	CG6660 / 42708	FlyBaseID:	FBgn0039030	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001262255.1	Gene:	CG31523 / 326148	FlyBaseID:	FBgn0051523	Length:	354	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	98/260 - (37%)
Similarity:	139/260 - (53%)	Gaps:	14/260 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RDLYAEHGDPRVAHLPLLGNLWIVLAIVALYVAFVLHYGPRWMANRAPFELKRVMQVYNVVQVLA 74
            |||.....||||....||.:....|.:...|..|....|||.||.|.|.||:.|:.|||.:|.:.
  Fly    13 RDLMDNKSDPRVNDFFLLSSPLPTLCMCIFYAYFSKSLGPRLMAKRKPMELRSVLVVYNAIQTIF 77

  Fly    75 NATIFVIGLSNTYLQPG----YSWTCQPVDHTDRSPAMMKTLYASYAYYMLKYLDLLDTVFIVLR 135
            :|.||.     .||..|    ||..|||||::....| |:.:...:.||:.|:.:..||:|.:||
  Fly    78 SAWIFY-----EYLMSGWWGHYSLKCQPVDYSTTGLA-MRMVNICWWYYISKFTEFFDTLFFILR 136

  Fly   136 KKNSQVSFLHVYHHGGMVFGVSIFMTFLGGSHCSMLGIINLLVHTVMYAYYYAASLG-AVKNLLW 199
            |||..||.|||.|||.|.|.|.:.:.|..|.|.:...::|..||.|||.||..|::| ..:..:|
  Fly   137 KKNEHVSTLHVIHHGCMPFSVWMGLKFAPGGHSTFFALLNSFVHIVMYFYYMIAAMGPKYQKYIW 201

  Fly   200 WKQRITQLQLMQFGYLTFHFLLVIVRNPCQFPV-FIAFIGFIQNIFMFSMFFDFYCKTYIRKQRK 263
            ||:.:|..|::||..:..|...::.|. |.:|. |:.:||....:|:| :|.|||...|:...|:
  Fly   202 WKKYLTTFQMVQFVAIFTHQFQLLFRE-CDYPKGFMVWIGLHGVMFLF-LFSDFYKAKYLNAARR 264

Fly 264 263
Fly 265 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6660	NP_651104.1	ELO	25..265	CDD:279492	91/245 (37%)
CG31523	NP_001262255.1	ELO	28..265	CDD:279492	91/245 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449642
Domainoid	1	1.000	108	1.000	Domainoid score	I1638
eggNOG	1	0.900	-	-		E1_KOG3071
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2130
Isobase	1	0.950	-	0	Normalized mean entropy	S2719
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	1	1.000	-	-		otm3414
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
	11	10.850