| Sequence 1: | NP_524454.2 | Gene: | klg / 42707 | FlyBaseID: | FBgn0017590 | Length: | 545 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_006781.1 | Gene: | MYOT / 9499 | HGNCID: | 12399 | Length: | 498 | Species: | Homo sapiens |
| Alignment Length: | 397 | Identity: | 93/397 - (23%) |
|---|---|---|---|
| Similarity: | 141/397 - (35%) | Gaps: | 106/397 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 61 HAGS--------------GGFAVEAAISNRGSNSRSM-----SNVQQSAV-----AASTLTAT-- 99
Fly 100 -LPRFLSRGH----TYRAVVGD-TLVLPCQVENLGNFVLLWRRGTNVLTASNIMVTRDERV--RL 156
Fly 157 IDGYNLEISDLEPQDAGDYVCQISDKIN----RDQVHTVEI-------------------LVPPS 198
Fly 199 VRAIPTSGQLQARKGGPITLECKGSGNPVPSIYW------TKKSGANKSTARIGDGPILTLEKLE 257
Fly 258 RQQAGVYQCTADNGVGDPVTVDMRLDVL-----------YPPDIQVEKSWIHSGEGFEAKLVCIV 311
Fly 312 FADPVATVSWYQNSFPIQ-STDR-RIMATRANRHMLTIRHIQQEDFGNYSCVADNSLG--RSRKY 372
Fly 373 MELSGRP 379 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| klg | NP_524454.2 | DUF1370 | 63..>124 | CDD:284518 | 21/92 (23%) |
| IG_like | 109..195 | CDD:214653 | 21/111 (19%) | ||
| Ig | 118..191 | CDD:143165 | 18/78 (23%) | ||
| IG_like | 205..274 | CDD:214653 | 16/74 (22%) | ||
| IGc2 | 213..273 | CDD:197706 | 16/65 (25%) | ||
| IGc2 | 301..367 | CDD:197706 | 21/67 (31%) | ||
| FN3 | 392..486 | CDD:238020 | |||
| MYOT | NP_006781.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..46 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 64..151 | 19/76 (25%) | |||
| Necessary for interaction with ACTN1 | 79..150 | 16/72 (22%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 202..241 | 9/41 (22%) | |||
| Necessary for interaction with ACTA1. /evidence=ECO:0000269|PubMed:12499399 | 215..498 | 57/239 (24%) | |||
| Necessary for interaction with FLNC | 215..493 | 57/239 (24%) | |||
| Ig | 249..333 | CDD:299845 | 20/86 (23%) | ||
| I-set | 250..340 | CDD:254352 | 21/92 (23%) | ||
| I-set | 349..440 | CDD:254352 | 26/96 (27%) | ||
| Ig_Myotilin_C | 366..440 | CDD:143300 | 20/73 (27%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR45080 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 2.010 | |||||