DRSC/TRiP Functional Genomics Resources

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Protein Alignment klg and opcml

DIOPT Version :10

Sequence 1:NP_524454.2 Gene:klg / 42707 FlyBaseID:FBgn0017590 Length:545 Species:Drosophila melanogaster
Sequence 2:NP_001072487.1 Gene:opcml / 779942 XenbaseID:XB-GENE-5831850 Length:346 Species:Xenopus tropicalis


Alignment Length:274 Identity:79/274 - (28%)
Similarity:130/274 - (47%) Gaps:14/274 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   115 GDTLVLPCQVENLGNFVLLWRRGTNVLTASNIMVTRDERVRLI----DGYNLEISDLEPQDAGDY 175
            ||:.:|.|.|:|....| .|...:.:|...|...:.|.||.|:    ..|::||.:::..|.|.|
 Frog    52 GDSAILRCTVDNRVTRV-AWLNRSTILYTGNDKWSIDPRVVLLANTKSQYSIEIQNVDIYDEGPY 115

  Fly   176 VCQISDKINRDQVHTVEILVPPSVRAIPTSGQLQARKGGPITLECKGSGNPVPSIYWTKKSGANK 240
            .|.:... |..:...|.::|..:.:.:..|..:...:|..:.|.|..:|.|.|::.|...:|  |
 Frog   116 TCSVQTD-NHPKTSRVHLIVQVAPQILNISSDITVNEGSTVALRCLATGRPEPAVTWRHFTG--K 177

  Fly   241 STARIGDGPILTLEKLERQQAGVYQCTADNGVGDPVTVDMRLDVLYPPDIQVEKSWIHSGEGFEA 305
            |...:.|...|.:..:.|.|:|.|:|:|.|.|..|....:|:.|.|||.|...:   ::|.....
 Frog   178 SHRFVSDDEYLEITGITRDQSGQYECSAANDVSAPDIRKVRVTVNYPPYISDTR---NTGASLGQ 239

  Fly   306 K--LVCIVFADPVATVSWYQNSFPI-QSTDRRIMATRANRHMLTIRHIQQEDFGNYSCVADNSLG 367
            |  |.|...|.|:|...||:....: ...|...:..:.:..:||..::.::|:|||:|||.|.||
 Frog   240 KGILRCSASAVPLAEFQWYREETRLANGLDGVRIENKDHMSILTFFNVSEKDYGNYTCVASNKLG 304

  Fly   368 RSRKYMELSGRPGA 381
            .|...:.|...|||
 Frog   305 NSNASVILYAGPGA 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klgNP_524454.2 IG_like 109..195 CDD:214653 23/83 (28%)
Ig strand B 118..122 CDD:409353 1/3 (33%)
Ig strand C 131..135 CDD:409353 1/3 (33%)
Ig strand E 160..164 CDD:409353 1/3 (33%)
Ig strand F 174..179 CDD:409353 2/4 (50%)
Ig strand G 188..191 CDD:409353 0/2 (0%)
Ig_3 196..270 CDD:464046 19/73 (26%)
Ig_3 287..364 CDD:464046 22/79 (28%)
FN3 392..486 CDD:238020
opcmlNP_001072487.1 Ig 46..134 CDD:472250 23/83 (28%)
Ig strand B 55..59 CDD:409353 1/3 (33%)
Ig strand C 67..71 CDD:409353 1/4 (25%)
Ig strand E 100..104 CDD:409353 1/3 (33%)
Ig strand F 114..119 CDD:409353 2/4 (50%)
Ig strand G 127..130 CDD:409353 0/2 (0%)
Ig_3 138..207 CDD:464046 19/70 (27%)
Ig_3 224..301 CDD:464046 22/79 (28%)
Blue background indicates that the domain is not in the aligned region.

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