DRSC/TRiP Functional Genomics Resources

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Protein Alignment klg and ush2a

DIOPT Version :9

Sequence 1:NP_524454.2 Gene:klg / 42707 FlyBaseID:FBgn0017590 Length:545 Species:Drosophila melanogaster
Sequence 2:XP_009291422.1 Gene:ush2a / 568982 ZFINID:ZDB-GENE-060503-794 Length:5243 Species:Danio rerio


Alignment Length:396 Identity:93/396 - (23%)
Similarity:138/396 - (34%) Gaps:93/396 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   187 QVHTVEILVPPSVRAIPTSGQLQARKGGPITL---------ECKGSGNPVPSIY----------W 232
            |.:||..|||.|....    |:.|..||..||         |......|.|:|.          |
Zfish  2218 QDYTVRNLVPGSTYLF----QIAACTGGGCTLSDPSTART
EESSPEEVPAPNILSLSPHSLHLSW 2278

  Fly   233 T---KKSGANKSTARIGDGPILTLEKLERQQAG-----------VYQCTADNGVGDPVTVDMRLD 283
            |   |.:|...|.....||.::....|...:.|           |..|||......|:.....|:
Zfish  2279 TPPRKPNGVISSYGLWMDGTLVQNSSLMASEVGDLSPWSLHSFRVQACTAQGCALGPLVESRTLE 2343

  Fly   284 VLYPP------------DIQVEKSWIHSGEGFEAKLVCIVFADPVATVSWYQNSFPIQSTD---R 333
            :  ||            ...|...|....|........::||.|      .||...:.:.|   |
Zfish  2344 M--PPVGHVTLVVFSETPHSVRAKWEAPAEPNGNLTYTVLFAGP------GQNFSSLDTPDTEMR 2400

  Fly   334 RIMATRANRHMLTIRHIQQEDFGNYSCV--ADNSLG-RSRKYMELSGRPGAAE-FYSPKW-GRSP 393
            .:::|......::|..:.  .:.|||.:  |.|||| .....:.:|..|||.: ..:|:. ..:|
Zfish  2401 ELLSTGKEGQWVSIGGLL--PYSNYSVMVKACNSLGCVESSPVSVSLPPGAPDGLLAPRLAAATP 2463

  Fly   394 DSYNLTWKI---DSYPPLEEVRLLYRRVQMNETYQQPGRWHDFILTPEHRPASEPLTHIMSYTIK 455
            .|..::|..   .:.|.....||..|.....:.:|        ::..|        |...|:|:.
Zfish  2464 TSLQVSWAAPARHNAPGALRYRLQMRSSASTQLHQ--------LMDDE--------TTTFSHTVT 2512

  Fly   456 NLHPGGYYEAIVQAKNRYGWNEVSDIFQFVVATNSQD-IGPEDAEVVASSKSRSN--SASIGSLP 517
            :|.|...|...:...|.||  |.|.  .:|....:|| .|..|..|::..:|||.  |.|..|.|
Zfish  2513 DLEPFTEYHFRLLVSNSYG--ETSS--PWVSLFTAQDRPGAVDPPVLSDIQSRSAFISWSPPSQP 2573

  Fly   518 GSTVLH 523
            ...:.|
Zfish  2574 NGIITH 2579

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klgNP_524454.2 DUF1370 63..>124 CDD:284518
IG_like 109..195 CDD:214653 3/7 (43%)
Ig 118..191 CDD:143165 1/3 (33%)
IG_like 205..274 CDD:214653 23/101 (23%)
IGc2 213..273 CDD:197706 21/92 (23%)
IGc2 301..367 CDD:197706 16/70 (23%)
FN3 392..486 CDD:238020 20/96 (21%)
ush2aXP_009291422.1 Laminin_G_3 160..297 CDD:290121
Laminin_N 307..528 CDD:295486
EGF_Lam 529..577 CDD:238012
EGF_Lam 586..638 CDD:238012
Laminin_EGF 653..703 CDD:278482
Laminin_EGF 706..756 CDD:278482
EGF_Lam 759..797 CDD:214543
Laminin_EGF 808..857 CDD:278482
EGF_Lam 859..912 CDD:238012
EGF_Lam 913..963 CDD:238012
EGF_Lam 965..1014 CDD:238012
EGF_Lam 1015..1064 CDD:238012
FN3 1177..1253 CDD:238020
FN3 1264..1375 CDD:238020
FN3 1386..1469 CDD:214495
LamG 1537..1699 CDD:238058
LamG 1737..1890 CDD:238058
FN3 1981..2071 CDD:238020
FN3 2163..2253 CDD:238020 13/38 (34%)
FN3 2258..2341 CDD:238020 17/82 (21%)
FN3 2352..2443 CDD:238020 20/98 (20%)
FN3 2447..2544 CDD:238020 25/116 (22%)
FN3 2547..2633 CDD:238020 11/33 (33%)
FN3 2635..2733 CDD:238020
FN3 2743..2807 CDD:238020
FN3 2830..2932 CDD:238020
fn3 2939..3014 CDD:278470
FN3 3032..>3099 CDD:238020
FN3 3542..3611 CDD:238020
FN3 3615..3701 CDD:238020
fn3 3718..3784 CDD:278470
FN3 3801..3887 CDD:238020
FN3 3908..3971 CDD:238020
FN3 3996..4086 CDD:238020
FN3 4186..4284 CDD:238020
fn3 4288..4366 CDD:278470
FN3 4382..4465 CDD:238020
FN3 4470..4553 CDD:238020
FN3 4555..4653 CDD:238020
FN3 4679..4753 CDD:238020
fn3 4760..4830 CDD:278470
FN3 4864..4955 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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