DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klg and dpr18

DIOPT Version :9

Sequence 1:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	387	Identity:	85/387 - (21%)
Similarity:	148/387 - (38%)	Gaps:	122/387 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PITAHASANANASGLRK---SSQRRNRAPLQMNCPILIVISLGWLLHAHAGSGGFAVEAAISNRG 77
            |.||.||...:.|.:::   |::.||                      |..:.||   |.::.|
  Fly   166 PTTAFASLKVDRSTMKQPIDSTRTRN----------------------HWTASGF---ARVTER- 204

  Fly    78 SNSRSMSNVQ-----------QSAVAASTLTATLPRFLSRGHTYRAVVGDTLVLPCQVENLGNFV 131
              .||..:.:           .||.:...|.:.:..|..            .||.|:|..|.:..
  Fly   205 --PRSKHHHEHHWGPFFEEPINSATSGDNLVSAVHLFTE------------AVLNCRVGMLKDKT 255

  Fly   132 LLWRRGT----NVLTASNIMVTRDERVRL----IDGYNLEISDLEPQDAGDYVCQISDKINRDQV 188
            ::|.|.|    ::||..|:..:.|.|:|:    .:.:.|.|:..:.:|||.|:||:|....|...
  Fly   256 VMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLLINPTQTEDAGVYMCQVSTHPPRVFT 320

  Fly   189 HTVEILVPPSVRAIPTS----GQLQARKGGPITLECKGSGNPVPSIYWTKKSGANKSTARIGDGP 249
            ..:.:|.|| :|.|...    |....:.|..:.|:|:.|    .|.:..::....|||....|
  Fly   321 TNLTVLEPP-LRIIDEHERDVGDRYYKSGSTVDLQCQIS----RSFFQKERQTILKSTDSAND-- 378

  Fly   250 ILTLEKLERQQAGVYQCTAD-NGVGDPVTVDMRLDVLYPPDIQVEKSWIHSGEGFEAKLVCIVFA 313
              .::||      :.:.|:: |.:|:......:.                ||:..|...
  Fly   379 --AVQKL------INETTSELNLIGNVNQTQHKF----------------SGQDLEKYF------ 413

  Fly   314 DPVATVSWYQNSFPIQS-TDRRI------MATRANRHMLTIRHIQQEDFGNYSCVADNSLGR 368
              ...::|.::..|:|. |:||:      :.:|     ::|...:..|.|||||    ||||
  Fly   414 --TKFITWAKDEEPLQGMTNRRLSVSDVWLTSR-----ISIGDAKLSDSGNYSC----SLGR 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	13/71 (18%)
		IG_like	109..195	CDD:214653	24/93 (26%)
		Ig	118..191	CDD:143165	24/80 (30%)
		IG_like	205..274	CDD:214653	14/73 (19%)
		IGc2	213..273	CDD:197706	13/60 (22%)
		IGc2	301..367	CDD:197706	16/72 (22%)
		FN3	392..486	CDD:238020
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	24/82 (29%)
		Ig	<258..326	CDD:299845	19/67 (28%)
		IGc2	<417..461	CDD:197706	14/52 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810