DRSC/TRiP Functional Genomics Resources

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Protein Alignment klg and Iglon5

DIOPT Version :10

Sequence 1:NP_524454.2 Gene:klg / 42707 FlyBaseID:FBgn0017590 Length:545 Species:Drosophila melanogaster
Sequence 2:NP_001419161.1 Gene:Iglon5 / 308557 RGDID:1305344 Length:336 Species:Rattus norvegicus


Alignment Length:349 Identity:98/349 - (28%)
Similarity:147/349 - (42%) Gaps:59/349 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 LLHAHAGSGGFAVEAAISNRGSNSRSMSNVQQSAVAASTLTATLPRFLSRGHTYRAVVGDTLVLP 121
            ||.|.|.:|     .|:.:||..|:|:                  .|.|....|....||...|.
  Rat    12 LLAAAALAG-----LAVISRGLLSQSL------------------EFSSPADNYTVCEGDNATLS 53

  Fly   122 CQVENLGNFVLLWRRGTNVLTASNIMVTRDERVRLI----DGYNLEISDLEPQDAGDYVCQISDK 182
            |.::.....| .|...:|:|.|.|...|.|.||||:    :.:::.|:.:...|.|.|.|...  
  Rat    54 CFIDEHVTRV-AWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITQVGLGDEGLYTCSFQ-- 115

  Fly   183 INRDQVHTVEI--LVPPSVRAIPTSGQLQARKGGPITLECKGSGNPVPSIYWTKKSGANKSTARI 245
             .|.|.:|.::  :|....|.:..|..:...:||.:.|.|...|.|.|::.|.:......|    
  Rat   116 -TRHQPYTTQVYLIVHVPARIVNISSPVAVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTS---- 175

  Fly   246 GDGPILTLEKLERQQAGVYQCTADNGVGD-PVTVDMRLDVLYPPDIQVEKSWIHSGEGFEAKLVC 309
             :|.||.:..::|.|||.|:|...|||.. |.:..:.:.|.|||.| .:.:...:..|..|.|.|
  Rat   176 -EGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTI-TDVTSARTALGRAALLRC 238

  Fly   310 IVFADPVATVSWYQNSFPIQSTDRRIMA----------TRANRHMLTIRHIQQEDFGNYSCVADN 364
            ...|.|.|...||:        |.|:::          |...|.||...::....:|||:|.|.|
  Rat   239 EAMAVPPADFQWYK--------DDRLLSSGSAEGLKVQTERTRSMLLFANVSARHYGNYTCRAAN 295

  Fly   365 SLGRSRKYMELSGRPGAAEFYSPK 388
            .||.|...|.|. |||:.|..:|:
  Rat   296 RLGASSASMRLL-RPGSLENSAPR 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klgNP_524454.2 IG_like 109..195 CDD:214653 25/91 (27%)
Ig strand B 118..122 CDD:409353 1/3 (33%)
Ig strand C 131..135 CDD:409353 1/3 (33%)
Ig strand E 160..164 CDD:409353 0/3 (0%)
Ig strand F 174..179 CDD:409353 2/4 (50%)
Ig strand G 188..191 CDD:409353 0/2 (0%)
Ig_3 196..270 CDD:464046 20/73 (27%)
Ig_3 287..364 CDD:464046 23/86 (27%)
FN3 392..486 CDD:238020
Iglon5NP_001419161.1 Ig 41..129 CDD:472250 25/91 (27%)
Ig strand B 50..54 CDD:409382 1/3 (33%)
Ig strand C 62..66 CDD:409382 1/4 (25%)
Ig strand E 95..99 CDD:409382 0/3 (0%)
Ig strand F 109..114 CDD:409382 2/4 (50%)
Ig strand G 122..125 CDD:409382 1/2 (50%)
Ig_3 134..199 CDD:464046 20/69 (29%)
Ig_3 217..295 CDD:464046 23/86 (27%)
Blue background indicates that the domain is not in the aligned region.

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