Protein Alignment klg and Cntn4

DIOPT Version :10

• Sequence 1: NP_524454.2
• Gene: klg / 42707
• FlyBaseID: FBgn0017590
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001103219.1
• Gene: Cntn4 / 269784
• MGIID: 1095737
• Length: 1026
• Species: Mus musculus
• Alignment Length: 388
• Identity: 97/388 - (25%)
• Similarity: 162/388 - (41%)
• Gaps: 77/388 - (19%)

  Fly   120 LPCQVENLGNFVLLWRRGTNVLTASNIMVTRDERVRLIDGYNLEISDLEPQDAGDYVCQISDK-- 182
            |.|:|:......:.|:     :..:::.:..|.|..::||..|..:..:.||||.|.|..::.
Mouse    48 LSCEVKGNPKPHIRWK-----INGTDVDIGMDFRYSVVDGSLLINNPNKTQDAGTYQCIATNSFG 107

  Fly   183 --INRDQVHTVEILVPPSVRAIPTSGQLQARKGGPITLEC---KGSG--------NPVPSIYWTK 234
              ::|:.......|.....|   |...:..|:|..:.|.|   ..||        |..|| |...
Mouse   108 TIVSREAKLQFAYLENFKTR---TRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPS-YQDN 168

  Fly   235 KSGANKSTARIGDGPILTLEKLERQQAGVYQCTADNGV------GDPVTVDMRLDVL---YPPDI 290
            :...::.|..      |.:.|:|:...|.|.|...|.|      |.|..:.:|.|.:   |.|.|
Mouse   169 RRFVSQETGN------LYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKI 227

  Fly   291 QVE-KSWIHSGEGFEAKLVCIVFADPVATVSWYQNSFPIQSTDRRIMATRANRH----MLTIRHI 350
            :|: ...:.:.:|...||.|....:||.|:.|       :..|.:.:|.:|.||    :|.|.:.
Mouse   228 EVQFPETVPAEKGTTVKLECFALGNPVPTILW-------RRADGKPIARKARRHKSNGILEIPNF 285

  Fly   351 QQEDFGNYSCVADNSLGRSRKYMELSGRPGAAEFYS-PKWGRSPDSYNLTWKIDSYPPLEEVRLL 414
            ||||.|:|.|||:||.|:       :...|...||: |.|.:..:        |.:..:||  .:
Mouse   286 QQEDAGSYECVAENSRGK-------NVAKGQLTFYAQPNWVQIIN--------DIHVAMEE--SV 333

  Fly   415 YRRVQMNETYQQPGRW---HDFILTPEHRPASEPLTHIMSYTIKNLHPGGYYEAIVQAKNRYG 474
            :...:.|...:...||   .|.:||.:.....:...:|   ||.||...|.|:.:  |:|::|
Mouse   334 FWECKANGRPKPTYRWLKNGDPLLTRDRIQIEQGTLNI---TIVNLSDAGMYQCV--AENKHG 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klg	NP_524454.2	IG_like	109..195	CDD:214653	16/78 (21%)
		Ig strand B	118..122	CDD:409353	1/1 (100%)
		Ig strand C	131..135	CDD:409353	0/3 (0%)
		Ig strand E	160..164	CDD:409353	1/3 (33%)
		Ig strand F	174..179	CDD:409353	2/4 (50%)
		Ig strand G	188..191	CDD:409353	0/2 (0%)
		Ig_3	196..270	CDD:464046	19/84 (23%)
		Ig_3	287..364	CDD:464046	27/81 (33%)
		FN3	392..486	CDD:238020	19/86 (22%)
Cntn4	NP_001103219.1	Ig	25..120	CDD:472250	16/76 (21%)
		Ig strand B	46..50	CDD:409353	1/1 (100%)
		Ig strand C	59..63	CDD:409353	0/3 (0%)
		Ig strand E	82..86	CDD:409353	1/3 (33%)
		Ig strand F	97..102	CDD:409353	2/4 (50%)
		Ig strand G	111..114	CDD:409353	1/2 (50%)
		Ig	129..213	CDD:472250	21/90 (23%)
		Ig strand B	140..144	CDD:409353	1/3 (33%)
		Ig strand C	154..158	CDD:409353	0/3 (0%)
		Ig strand E	177..181	CDD:409353	1/9 (11%)
		Ig strand F	191..196	CDD:409353	2/4 (50%)
		Ig strand G	207..210	CDD:409353	1/2 (50%)
		Ig	225..313	CDD:472250	31/101 (31%)
		Ig strand B	243..247	CDD:409353	2/3 (67%)
		Ig strand C	256..260	CDD:409353	2/10 (20%)
		Ig strand E	278..282	CDD:409353	1/3 (33%)
		Ig strand F	292..297	CDD:409353	2/4 (50%)
		Ig strand G	305..308	CDD:409353	0/2 (0%)
		Ig	318..401	CDD:472250	20/89 (22%)
		Ig strand B	333..337	CDD:409353	0/3 (0%)
		Ig strand C	346..350	CDD:409353	1/3 (33%)
		Ig strand E	367..371	CDD:409353	0/3 (0%)
		Ig strand F	381..386	CDD:409353	1/6 (17%)
		Ig strand G	394..397	CDD:409353
		Ig	406..494	CDD:472250
		Ig strand B	425..429	CDD:409353
		Ig strand C	438..442	CDD:409353
		Ig strand E	460..464	CDD:409353
		Ig strand F	474..479	CDD:409353
		Ig strand G	487..490	CDD:409353
		Ig6_Contactin-4	496..597	CDD:409439
		Ig strand A	496..502	CDD:409439
		Ig strand A'	505..510	CDD:409439
		Ig strand B	513..521	CDD:409439
		Ig strand C	530..534	CDD:409439
		Ig strand D	555..558	CDD:409439
		Ig strand E	559..563	CDD:409439
		Ig strand F	572..579	CDD:409439
		FN3	580..>1014	CDD:442628
		Ig strand G	586..590	CDD:409439
		FN3	597..690	CDD:238020
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	685..710
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	886..906