DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klg and zig-4

DIOPT Version :9

Sequence 1:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	216	Identity:	47/216 - (21%)
Similarity:	78/216 - (36%)	Gaps:	56/216 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 VEILVPPSVRAIPTSGQLQARKGGPITLECKGSGNPVPSIYWTKKSG---------------ANK 240
            ::|:.|.....||        .|....|.|.....|..:|:| |.:|               .|.
Worm    46 IKIVAPLESALIP--------GGETYQLRCDIMSTPAATIHW-KFNGKLIQGSNELNVEEKLLNF 101

  Fly   241 STARIGDG---PILTLEKLERQQAGVYQCTADNGVGDPVTVDMRLDVLYPPDIQVEKSWIHSGE- 301
            ..|.:..|   .|||::....:.:|.|.|...||       ...::.:...:|:.|.|...|..
Worm   102 GKAIVDTGIVASILTIQCPSAENSGTYSCVGYNG-------HQTIETVAEVEIEGEASGCRSNHK 159

  Fly   302 ----------------GFEAKLVCIVFADPVATVSWYQNSFPIQSTDRRIMATRANRHMLTIRHI 350
                            |..|.|||  .|:......|..|...:::.|:..:.:..:   |.|::|
Worm   160 SAPEIVFWTDSRFEMTGNVATLVC--RANQQVDWVWMSNDELVKNNDKFTVLSNGD---LVIKNI 219

  Fly   351 QQEDFGNYSCVADNSLGRSRK 371
            ..:|.|.|:|:|.|..|.:|:
Worm   220 VWDDMGTYTCIARNQFGEARQ 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klg	NP_524454.2	DUF1370	63..>124	CDD:284518
		IG_like	109..195	CDD:214653	1/3 (33%)
		Ig	118..191	CDD:143165	47/216 (22%)
		IG_like	205..274	CDD:214653	19/86 (22%)
		IGc2	213..273	CDD:197706	19/77 (25%)
		IGc2	301..367	CDD:197706	18/82 (22%)
		FN3	392..486	CDD:238020
zig-4	NP_509335.1	I-set	47..147	CDD:254352	23/115 (20%)
		Ig	65..144	CDD:143165	18/86 (21%)
		IG_like	176..245	CDD:214653	20/70 (29%)
		Ig	<193..238	CDD:299845	13/47 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900