Protein Alignment klg and Kirrel

DIOPT Version :9

• Sequence 1: NP_524454.2
• Gene: klg / 42707
• FlyBaseID: FBgn0017590
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_011238330.1
• Gene: Kirrel / 170643
• MGIID: 1891396
• Length: 805
• Species: Mus musculus
• Alignment Length: 586
• Identity: 114/586 - (19%)
• Similarity: 185/586 - (31%)
• Gaps: 191/586 - (32%)

  Fly    95 TLTATLP----RFLSRGHTYRAVVGDTLVLPCQVENLGNFVLLWRRGTNVLTASNIMVTRDERVR 155
            ||...||    ||.........|.|...||||.:.|....|...:.|..:.....:...  .|.|
Mouse    43 TLALALPGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAW--PRYR 105

  Fly   156 LIDG-----YNLEISDLEPQDAGDYVCQISDKINRDQVHTVEILVPPSVRAIPTSGQLQARKGGP 215
            ::..     |||||:|.|..|...|.||.::...|.:...:.:|:||....|.....:..:.|.|
Mouse   106 VVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTP 170

  Fly   216 ITLECKG-SGNPVPSIYW----TKKSGANKSTARIGDG------PILTLEKLERQQAGVYQCTAD 269
            ..|.|:. :..|..:|.|    |::.||..||..:.||      ..|.:|..:.....|:.|.:.
Mouse   171 YNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSM 235

  Fly   270 N-GVGDPVTVDMRLDVLYPPDI--QVEKSWIHSGE------------------------------ 301
            | .:.:.....:.|||.:||.:  .:|...:..||
Mouse   236 NEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGERVIFTCQATANPEILGYRWAKGGFLIEDAH 300

  Fly   302 -----------------------------------------------------GFEAKLVCIVFA 313
                                                                 |.:..|.|:...
Mouse   301 ESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVG 365

  Fly   314 DPVATVSWYQNS------FPIQSTDRRIMA-TRANRHMLTIRHIQQEDFGNYSCVADNSLGRSRK 371
            :|..|::|.:..      .|....:..:.| ..:|.:.|.::.:.|.|.|.|:|.|
Mouse   366 NPPLTLTWTKKDSNMGPRLPGSPPEANLSAQVLSNSNQLLLKSVTQADAGTYTCRA--------- 421

  Fly   372 YMELSGRPGAAEFYSPKWGRSP--------------DSYNLTWKIDSYPPLEEVRLLYRRVQMNE 422
               :..|.|.||...|.:...|              |...:...|.|.||.:.:...::     |
Mouse   422 ---IVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWK-----E 478

  Fly   423 TYQQPGRWHDFILTPEHRPASEPLTHIMSYTIKNLHPGGYYEAIVQAK-NRYGWNEVSDIFQFVV 486
            .:.:.|....:  |.|...:...:  :.:.||.|:     .||..|.. |...||
Mouse   479 NFLEVGTLERY--TVERTNSGSGV--LSTLTINNV-----MEADFQTHYNCTAWN---------- 524

  Fly   487 ATNSQDIGP-------EDAEVVASSKSRSNSASIGSLPGSTVLHTALLLALALSNCQF--DRRRL 542
                 ..||       |:.||:          .:|.:.|:|: ...:|:..:.:...|  .|||.
Mouse   525 -----SFGPGTAIIQLEEREVL----------PVGIIAGATI-GAGILVVFSFAALVFFLYRRRK 573

  Fly   543 G 543
            |
Mouse   574 G 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	12/32 (38%)
		IG_like	109..195	CDD:214653	23/90 (26%)
		Ig	118..191	CDD:143165	21/77 (27%)
		IG_like	205..274	CDD:214653	19/80 (24%)
		IGc2	213..273	CDD:197706	19/71 (27%)
		IGc2	301..367	CDD:197706	17/155 (11%)
		FN3	392..486	CDD:238020	19/108 (18%)
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	25/95 (26%)
		Ig2_KIRREL3-like	170..251	CDD:143236	19/80 (24%)
		Ig	255..336	CDD:386229	4/80 (5%)
		Ig_3	340..421	CDD:372822	15/80 (19%)
		Ig5_KIRREL3	439..536	CDD:143306	21/125 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900