Protein Alignment klg and LOC1280937

DIOPT Version :10

• Sequence 1: NP_524454.2
• Gene: klg / 42707
• FlyBaseID: FBgn0017590
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_061518554.1
• Gene: LOC1280937 / 1280937
• VectorBaseID: AGAMI1_000362
• Length: 537
• Species: Anopheles gambiae
• Alignment Length: 509
• Identity: 118/509 - (23%)
• Similarity: 204/509 - (40%)
• Gaps: 99/509 - (19%)

  Fly    80 SRSMSNVQQSAVAASTLTATLPRFLSRGHTYRAVVGDTLVLPCQVEN-LGNFVLLWRRGTNVLTA 143
            |:....:..:|:..:||       |::.:..:|...:.:.|.|.|.| ..|.:::|......:..
Mosquito    64 SQEKPEISDNALLGTTL-------LTKDYIEQARESEQVTLKCDVSNPTTNNIIIWYYNNKPIFQ 121

  Fly   144 SNIMVTRDERVRLIDGYNLEISDLEPQDAGDYVCQISDKINRDQVHTVEILVPP-------SVRA 201
            ..|.:..|.|......::|.|.:::..|.|.|.||:... |......:::|.||       ..:.
Mosquito   122 QLIRLIPDTRYERGPDFSLVIDNVQLTDEGVYSCQLLPN-NMTVKIELQLLTPPRDVHIMHGSKT 185

  Fly   202 IPTSGQLQARKGGPITLECKGSGNPVPSIYWTKKSG--ANKSTARIG---DGPILTLEKLERQQA 261
            |..:.::..| ...:.|.|...|:|.|.|.|..:..  ..:::.::|   ....|.:.:::.|.|
Mosquito   186 INDTIEMHQR-DRKVVLLCSAGGHPTPLITWAYRGRHLDEENSRQLGIKLRKEFLEIHEVKSQHA 249

  Fly   262 GVYQCTADNGVGDP----VTVDMRLD--------------VLYP------PDIQVEKSWIHSGEG 302
            |.|:|.|.||:|:|    |||.::.|              |..|      |.|....|:|::..|
Mosquito   250 GDYECMAQNGIGNPISQTVTVVVKDDSSEELEDDYMDDANVTAPPLEKGSPIIHKHSSYINTAIG 314

  Fly   303 FEAKLVCIVFADP-VATVSWYQNSFPIQSTDRRIMAT-----RANRHMLTIRHIQQEDFGNYSCV 361
            ...::||:..::| ...:.|.:|...:||...:.:.|     ..||..|||:::||:|...|.|.
Mosquito   315 ENVEMVCLYDSNPEPRKIQWIRNDEIVQSVPAQTIITNDHHNHHNRTRLTIKNVQQKDLQAYYCK 379

  Fly   362 ADNSLGRSRKYMELSGRPGAAEFYSPKWGRSPDSYNLT-WKIDSYPPLEEVRLLYR--------- 416
            .:|.||.:.....|...||.|....   ..|.|....| |||.|...:.|:.:|||
Mosquito   380 IENELGEAVSKTILGLTPGGAHLIH---SNSSDGLLHTWWKIHSIQQISEMLVLYRGENTKYIPV 441

  Fly   417 RVQMNETYQQPGRWHDFILTPEHRPASEPLTHIMSYTI-KNLH-PGGYYEAIVQAKNRYGWNEVS 479
            ..:::...|.|..:                    ::|| |::. |.|.:....:|:|..||:...
Mosquito   442 TTEISSHDQNPDGY--------------------TWTIRKSIRLPEGEWFVTARARNTEGWSSAE 486

  Fly   480 DI-FQFVVATNSQDIGPEDAEVVASSKSRSNSASIGSLPGSTVLHTALLLALAL 532
            .: .||.:.....:|   ....:..|.....:.|:|.|        ||||.|.|
Mosquito   487 SLPHQFQIRDAMDNI---QVASIGGSSGAHRTLSVGGL--------ALLLLLVL 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klg	NP_524454.2	IG_like	109..195	CDD:214653	18/86 (21%)
		Ig strand B	118..122	CDD:409353	1/3 (33%)
		Ig strand C	131..135	CDD:409353	0/3 (0%)
		Ig strand E	160..164	CDD:409353	1/3 (33%)
		Ig strand F	174..179	CDD:409353	2/4 (50%)
		Ig strand G	188..191	CDD:409353	0/2 (0%)
		Ig_3	196..270	CDD:464046	19/85 (22%)
		Ig_3	287..364	CDD:464046	24/88 (27%)
		FN3	392..486	CDD:238020	24/106 (23%)
LOC1280937	XP_061518554.1	None