DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klg and iglon5

DIOPT Version :9

Sequence 1:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	89/308 - (28%)
Similarity:	139/308 - (45%)	Gaps:	23/308 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 ASTLTATLPRFLSRGHTYRAVVGDTLVLPCQVENLGNFVLLWRRGTNVLTASNIMVTRDERVRLI 157
            |..|......|:.....|....||...|.|.:::....| .|...:|:|.|.....:.|.||:|:
Frog    19 AQVLFVQCTEFVPPADNYTVSQGDNATLSCLIDDKVTRV-AWLNRSNILYAGKDKWSIDSRVQLL 82

  Fly   158 DG----YNLEISDLEPQDAGDYVC--QISDKINRDQVHTVEILVPPSVRAIPTSGQLQARKGGPI 216
            ..    |::.|:.::..|.|.|.|  |..||.:..||:.: :.||..:  :..|..:...:|..:
Frog    83 TNTKSEYSIVITHVDVADEGLYTCSFQTEDKPHTSQVYLI-VQVPAKI--VNISSSVTVNEGSNV 144

  Fly   217 TLECKGSGNPVPSIYWTKKSGANKSTARIGDGPILTLEKLERQQAGVYQCTADNGVGDPVTVDMR 281
            .|:|...|.|.|:|.|.:.|....|     :|.:|.:.::.|||||.|:|...|||..|.|..::
Frog   145 NLQCLAVGKPEPTITWQQLSEGFSS-----EGELLEITEINRQQAGDYECVTSNGVSVPDTKKVQ 204

  Fly   282 LDVLYPPDIQVEKSWIHSGEGFEAKLVCIVFADPVATVSWYQNSFP--IQSTDRRIMATRANRHM 344
            :.|.|||.|...|: ..|..|..|.|.|...|.|.|...||::...  |..|:...:.|.::..:
Frog   205 ITVNYPPYITDVKN-AQSPVGRPATLRCKAMAVPPAEFEWYKDEKRRLISGTEGLSIKTESSWSV 268

  Fly   345 LTIRHIQQEDFGNYSCVADNSLGRSRKYMEL--SGRP---GAAEFYSP 387
            :...::....:|||:|:|.|.||.....:.|  .|.|   ||....||
Frog   269 IVFSNVTSRHYGNYTCLASNKLGSFNSSLRLLKPGDPLNQGATHMVSP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	8/30 (27%)
		IG_like	109..195	CDD:214653	25/91 (27%)
		Ig	118..191	CDD:143165	22/78 (28%)
		IG_like	205..274	CDD:214653	23/68 (34%)
		IGc2	213..273	CDD:197706	21/59 (36%)
		IGc2	301..367	CDD:197706	18/67 (27%)
		FN3	392..486	CDD:238020
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	25/93 (27%)
		IG_like	35..123	CDD:214653	25/89 (28%)
		Ig	126..207	CDD:299845	26/87 (30%)
		I-set	128..207	CDD:254352	25/85 (29%)
		I-set	210..299	CDD:254352	25/89 (28%)
		Ig	227..298	CDD:143165	19/70 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910