DRSC/TRiP Functional Genomics Resources

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Protein Alignment klg and igsf9b

DIOPT Version :9

Sequence 1:NP_524454.2 Gene:klg / 42707 FlyBaseID:FBgn0017590 Length:545 Species:Drosophila melanogaster
Sequence 2:XP_031761656.1 Gene:igsf9b / 100379858 XenbaseID:XB-GENE-5887265 Length:1392 Species:Xenopus tropicalis


Alignment Length:561 Identity:123/561 - (21%)
Similarity:199/561 - (35%) Gaps:111/561 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 TAHASANANASGLRKSSQRRNRAPLQMNCPILIVISLGWLLHAHAGSGGFAVEAAISNRGSNSRS 82
            ||..:.....|.||:.......:..|::...|.:.|:|                 ..:|||....
 Frog   162 TAFGNPKPTVSWLREGEFLGRTSKYQLSDGSLTISSIG-----------------REDRGSYMCR 209

  Fly    83 MSNVQQSAVAASTLTAT-LPRFLSRGHTYRAVVGDTLVLPCQVENL-GNFVLLWRRGTNVLTASN 145
            .:::|..||.::.|... .|..:|........:....:..||.|.. ||....|     .....|
 Frog   210 ATSIQGEAVHSTRLLVQGSPFIVSPPENITVNISQDALFTCQAEAYPGNLTYTW-----YWQEEN 269

  Fly   146 IMVTRDERVR---LIDGYNLEISDLEPQDAGDYVCQISDKINRDQVHTVEILVPPSVRAIPTSGQ 207
            :....|.::|   |||| .|.|..::|:|||.|.|..|:.:.|....:..:.|....|.:.....
 Frog   270 VFFKNDLKLRVRILIDG-TLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVVNMPPV 333

  Fly   208 LQARKGGPITLECKGSG-NPVPSIYWTKKSGANK----STARIGDGPILTLEKLERQQAGVYQCT 267
            :....|....:.|.... .||..:.|.|.....:    |..::.|...:.:|:...:..|.|.|.
 Frog   334 IYVPVGIHGHIRCPVEAVPPVTFVKWNKDGRPLRIDKFSGWKLLDDGTIHVEEATEELLGTYTCV 398

  Fly   268 ADNGVG----DPVTVDMRLDVLYPPDIQVEKSWIHSGE-GFEAKLVCIVFADPVATVSWYQNSFP 327
            ..|.:|    .|   ..||.:..||...|...|.:..| |.|..:.|....||..::||      
 Frog   399 PYNALGTMGQSP---PARLLLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPSISW------ 454

  Fly   328 IQSTDRRIMATRANRH------MLTIRHIQQEDFGNYSCVADN---SLGRSRKYMELSGRPGAAE 383
                 |::.....::|      .|..|.:.:||.|.:.|||.|   |:..|.....:...|    
 Frog   455 -----RKVGRPSFSKHSVLPSGSLQFRSLSKEDHGEWECVASNVVTSITASAHLTVIGTSP---- 510

  Fly   384 FYSPKWGR---SPDSYNLTWKIDSYPPLEEV-----RLLYRRVQMNETYQQPGRWHDFILTPEHR 440
             ::|...|   |.::.|::|:.......|:.     ..|.:|.|...        ||::..|...
 Frog   511 -HAPSNVRVVVSMNTANVSWEAGYDGGFEQTFSVWYGALIKRAQFGP--------HDWVSMPVPS 566

  Fly   441 PASEPLTHIMSYTIKNLHPGGYYEAIVQAKNRYGWNEVSDI-----FQFVVATNSQDIGPEDAEV 500
            .:|..|       :.:|.|...|:..|.|:|:.|.:..|::     ..|.:.|      ||...|
 Frog   567 GSSFLL-------VDSLDPETEYQFSVLAQNKLGTSSFSEVVTLRTLAFPLTT------PEPLLV 618

  Fly   501 VASSKSRSNSASIGSLPGSTVLHTALLLALALSNCQF--DR 539
            :.|.:         .|..:......||..|..||..|  ||
 Frog   619 LTSPR---------CLTANRTQQGVLLSWLPPSNHSFPLDR 650

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klgNP_524454.2 DUF1370 63..>124 CDD:284518 10/61 (16%)
IG_like 109..195 CDD:214653 23/89 (26%)
Ig 118..191 CDD:143165 23/76 (30%)
IG_like 205..274 CDD:214653 14/77 (18%)
IGc2 213..273 CDD:197706 13/64 (20%)
IGc2 301..367 CDD:197706 20/75 (27%)
FN3 392..486 CDD:238020 21/103 (20%)
igsf9bXP_031761656.1 IG 30..115 CDD:214652
I-set 139..225 CDD:400151 16/79 (20%)
Ig strand A 139..142 CDD:409353
Ig strand A' 148..151 CDD:409353
Ig strand B 157..164 CDD:409353 1/1 (100%)
Ig strand C 170..175 CDD:409353 1/4 (25%)
Ig strand D 185..189 CDD:409353 1/3 (33%)
Ig strand E 191..195 CDD:409353 1/3 (33%)
Ig strand F 204..212 CDD:409353 2/7 (29%)
Ig strand G 215..225 CDD:409353 3/9 (33%)
I-set 229..321 CDD:400151 25/97 (26%)
Ig strand B 246..250 CDD:409353 0/3 (0%)
Ig strand C 260..264 CDD:409353 1/8 (13%)
Ig strand E 286..290 CDD:409353 2/4 (50%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
Ig strand G 314..317 CDD:409353 0/2 (0%)
Ig 344..405 CDD:409353 12/60 (20%)
Ig strand C 355..360 CDD:409353 0/4 (0%)
Ig strand E 380..384 CDD:409353 0/3 (0%)
Ig strand F 394..399 CDD:409353 2/4 (50%)
Ig 429..505 CDD:416386 21/86 (24%)
Ig strand A' 429..432 CDD:409353 0/2 (0%)
Ig strand B 438..445 CDD:409353 1/6 (17%)
Ig strand C 451..456 CDD:409353 2/15 (13%)
Ig strand C' 458..460 CDD:409353 0/1 (0%)
Ig strand E 471..476 CDD:409353 1/4 (25%)
Ig strand F 484..492 CDD:409353 4/7 (57%)
Ig strand G 495..505 CDD:409353 2/9 (22%)
FN3 510..605 CDD:238020 23/114 (20%)
FN3 622..703 CDD:238020 9/38 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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