DRSC/TRiP Functional Genomics Resources

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Protein Alignment klg and dscam

DIOPT Version :9

Sequence 1:NP_524454.2 Gene:klg / 42707 FlyBaseID:FBgn0017590 Length:545 Species:Drosophila melanogaster
Sequence 2:XP_031751619.1 Gene:dscam / 100216449 XenbaseID:XB-GENE-921689 Length:2039 Species:Xenopus tropicalis


Alignment Length:591 Identity:134/591 - (22%)
Similarity:213/591 - (36%) Gaps:140/591 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MNIISRSIRTGALAPPITAHASANANASGLRKSSQRRN-RAPLQMNCPILIVISLGWLLHAHAGS 64
            :||.:..:|.|.:     ...:|| |::|:.....|.| |.|..:.....|....|...:.|...
 Frog   469 LNITNTQVRDGGV-----YRCTAN-NSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRV 527

  Fly    65 GGFAV-----------------EAAISNRGSNSRS-----------MSNV----QQSAVAASTLT 97
            .|:..                 :.|..|.|:...|           |.||    |.|...:..:|
 Frog   528 IGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKDVDEGEYMCNVLVQPQLSTSQSVHVT 592

  Fly    98 ATLPRFLSRGHTYRAVVGDTLVLPCQVENLGN--FVLLWRRGTNVLTASNIMVTRDERVRLID-G 159
            ..:|.|:....:.|..:|..:.:||.|.: |:  ..:.|::....:.|| :.||.|.    || .
 Frog   593 VKVPPFIQPFESQRFSIGQRVFIPCVVVS-GDLPITITWQKDGRPIPAS-LGVTIDN----IDFT 651

  Fly   160 YNLEISDLEPQDAGDYVCQISDKINRDQVHTVE------ILVPPSVRAIPTSGQLQARKGGPITL 218
            .:|.||:|.....|:|.|     |.|:....||      :.|||.....||  ......|..:.|
 Frog   652 SSLRISNLSLMHNGNYTC-----IARNDAAAVEHQSQLIVRVPPRFVVQPT--DQDGIYGKAVIL 709

  Fly   219 ECKGSGNPVPSIYWTKKSGA----------NKSTARIGDGPILTLEKLERQQAGVYQCTADNGVG 273
            .|...|.|||:|.|....||          |.....:.:|.:|....|| :.:|.|.|...|.||
 Frog   710 NCSAEGYPVPTIVWKYSKGAGVPQFQPIALNGRIQLLTNGSLLIKHVLE-EDSGYYLCKVSNDVG 773

  Fly   274 DPVTVDMRLDVLYPPDIQVEKSWIHSGEGFEAKLVCIVFADPVATVSWYQNSFPIQSTDRRIMAT 338
            ..|:..|.|.|..|..|....:...:.:|.:.::.|....:....|.|       :..||.|...
 Frog   774 ADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRW-------EKEDRMINVP 831

  Fly   339 RANRHMLTIRHIQQ-------------EDFGNYSCVADNSLGRSRKYMELSGRPGAAEFYSPKWG 390
            ..:|::::.:.:.:             ||.|.:||.|.||.|..|..::|:.:            
 Frog   832 EMSRYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSFGEDRGIIQLTVQ------------ 884

  Fly   391 RSPDSYNLTWKIDSYPPLEEVR-LLYRRVQMNETYQQPGR----------------WHDFILTPE 438
            ..||           ||..|:| :..|.:.:..|....|.                |.....|.:
 Frog   885 EPPD-----------PPEIEIREVRARSIALRWTMGFDGNSPITGYDIECKNKSDSWDSVQRTKD 938

  Fly   439 HRPASEPLTHIMSYTIKNLHPGGYYEAIVQAKNRYGWNEVSDIFQFVVATNSQDIGPEDAEV--V 501
            ..|      .:...||.:|||...|...:.||||.|.:|.|:.........:.|..|::.::  :
 Frog   939 VSP------QLNQATIIDLHPASTYNIRMYAKNRIGKSEASNELTITTEEAAPDGPPQEVQLDPI 997

  Fly   502 ASSKSR 507
            :|...|
 Frog   998 SSQSIR 1003

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klgNP_524454.2 DUF1370 63..>124 CDD:284518 17/92 (18%)
IG_like 109..195 CDD:214653 25/94 (27%)
Ig 118..191 CDD:143165 21/75 (28%)
IG_like 205..274 CDD:214653 21/78 (27%)
IGc2 213..273 CDD:197706 20/69 (29%)
IGc2 301..367 CDD:197706 16/78 (21%)
FN3 392..486 CDD:238020 25/110 (23%)
dscamXP_031751619.1 Ig 26..121 CDD:416386
Ig strand A' 33..37 CDD:409353
Ig strand B 40..49 CDD:409353
Ig strand C 55..61 CDD:409353
Ig strand C' 63..66 CDD:409353
Ig strand D 72..75 CDD:409353
Ig strand E 80..85 CDD:409353
Ig strand F 98..106 CDD:409353
Ig strand G 109..121 CDD:409353
Ig 124..217 CDD:416386
Ig strand A' 127..136 CDD:409353
Ig strand B 140..147 CDD:409353
Ig strand C 157..162 CDD:409353
Ig strand C' 164..167 CDD:409353
Ig strand D 172..176 CDD:409353
Ig strand E 179..185 CDD:409353
Ig strand F 193..201 CDD:409353
Ig strand G 205..217 CDD:409353
Ig strand A 225..228 CDD:409353
Ig strand A' 234..237 CDD:409353
IG_like 236..310 CDD:214653
Ig strand B 242..249 CDD:409353
Ig strand C 255..260 CDD:409353
Ig strand C' 262..264 CDD:409353
Ig strand D 270..274 CDD:409353
Ig strand E 276..280 CDD:409353
Ig strand F 289..297 CDD:409353
Ig strand G 300..310 CDD:409353
Ig 313..395 CDD:416386
Ig strand A 314..319 CDD:409353
Ig strand A' 322..326 CDD:409353
Ig strand B 329..339 CDD:409353
Ig strand C 344..350 CDD:409353
Ig strand C' 351..354 CDD:409353
Ig strand E 368..374 CDD:409353
Ig strand F 381..389 CDD:409353
Ig 406..501 CDD:416386 9/37 (24%)
Ig strand A 406..409 CDD:409353
Ig strand A' 415..419 CDD:409353
Ig strand B 422..431 CDD:409353
Ig strand C 436..442 CDD:409353
Ig strand C' 444..447 CDD:409353
Ig strand D 452..460 CDD:409353
Ig strand E 464..473 CDD:409353 2/3 (67%)
Ig strand F 480..488 CDD:409353 2/13 (15%)
Ig strand G 491..501 CDD:409353 2/9 (22%)
Ig 504..593 CDD:416386 14/88 (16%)
Ig strand A 505..507 CDD:409353 0/1 (0%)
Ig strand A' 512..516 CDD:409353 1/3 (33%)
Ig strand B 519..526 CDD:409353 1/6 (17%)
Ig strand C 533..539 CDD:409353 0/5 (0%)
Ig strand C' 540..542 CDD:409353 0/1 (0%)
Ig strand D 549..553 CDD:409353 0/3 (0%)
Ig strand E 557..563 CDD:409353 1/5 (20%)
Ig strand F 571..579 CDD:409353 3/7 (43%)
Ig strand G 583..593 CDD:409353 1/9 (11%)
Ig 596..686 CDD:416386 27/100 (27%)
Ig strand A 597..599 CDD:409353 0/1 (0%)
Ig strand A' 604..608 CDD:409353 1/3 (33%)
Ig strand B 611..620 CDD:409353 2/8 (25%)
Ig strand C 625..632 CDD:409353 1/6 (17%)
Ig strand C' 634..636 CDD:409353 0/1 (0%)
Ig strand D 643..648 CDD:409353 3/8 (38%)
Ig strand E 651..658 CDD:409353 2/6 (33%)
Ig strand F 665..673 CDD:409353 4/12 (33%)
Ig strand G 676..685 CDD:409353 2/8 (25%)
Ig_DSCAM 689..784 CDD:409397 29/97 (30%)
Ig strand B 707..711 CDD:409397 1/3 (33%)
Ig strand C 720..724 CDD:409397 1/3 (33%)
Ig strand E 749..753 CDD:409397 1/3 (33%)
Ig strand F 763..768 CDD:409397 2/4 (50%)
Ig strand G 777..780 CDD:409397 0/2 (0%)
Ig_DSCAM 785..885 CDD:409398 21/118 (18%)
Ig strand B 805..809 CDD:409398 0/3 (0%)
Ig strand C 818..822 CDD:409398 2/10 (20%)
Ig strand E 849..853 CDD:409398 0/3 (0%)
Ig strand F 863..868 CDD:409398 2/4 (50%)
Ig strand G 876..879 CDD:409398 1/2 (50%)
FN3 886..980 CDD:238020 25/110 (23%)
FN3 987..1084 CDD:238020 3/17 (18%)
FN3 1093..1185 CDD:238020
FN3 1190..1279 CDD:238020
Ig_3 <1303..1364 CDD:404760
Ig strand B 1304..1311 CDD:409353
Ig strand C 1317..1322 CDD:409353
Ig strand C' 1327..1333 CDD:409353
Ig strand D 1337..1341 CDD:409353
Ig strand E 1343..1347 CDD:409353
Ig strand F 1356..1364 CDD:409353
Ig strand G 1367..1377 CDD:409353
FN3 1381..1471 CDD:238020
FN3 1497..1568 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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