Protein Alignment CG4704 and micu-1

DIOPT Version :10

• Sequence 1: NP_651103.1
• Gene: CG4704 / 42706
• FlyBaseID: FBgn0039029
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001255723.1
• Gene: micu-1 / 178287
• WormBaseID: WBGene00013462
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 377
• Identity: 128/377 - (33%)
• Similarity: 206/377 - (54%)
• Gaps: 35/377 - (9%)

  Fly     1 MQYENRLRLHAHPTKIFRYFATIKM---KNKSGKWELYMTPNDFLRSIQPGLKQPENLGLDKFQI 62
            ::||:||||::.|.||||||||:|:   ...||::|::|||.|||||..||:.||...|||.|:.
 Worm   166 IEYEDRLRLYSTPDKIFRYFATLKIIDPNEDSGRFEVFMTPEDFLRSFTPGVMQPRRWGLDSFKN 230

  Fly    63 L--DEHAANKWIPEVKDDSIFLKIEKRGLLTYSDYVLLTILLSIPERNVRISFKLFDLNGDGDVT 125
            .  ::|..:|:   ...||||.|:.:.||:.:|||:.|..|||....:..::||:||::|:|.:.
 Worm   231 YNPEKHKRHKF---SDPDSIFYKLGENGLINFSDYLFLMTLLSTSHADFALAFKIFDVDGNGALD 292

  Fly   126 IDELDTV-FMAMTQGEVSM---------------MNSHLKSHFFGHRLNKTLSIDEFLKFLHALH 174
            .:|...| .:.|:|..|..               .||.|:::|||.....:||.::|::|...|.
 Worm   293 KEEFTKVQQLIMSQTTVGQRHRDHITPNQSFRVETNSALETYFFGKDGKGSLSSEKFIEFQERLQ 357

  Fly   175 IEIHTDQFQ--NLLKESSSVISELDFAKVVLGLRKSRSERRE--ILKRVKKKF-GQMDHGITLEE 234
            .:|...:|:  :.|.....:|:|..||:::| |....:|:::  :|||||::| |:...||:..|
 Worm   358 HDILKMEFERRDALDNPDGLINEDSFAQLLL-LHAQINEKKQKHMLKRVKRRFKGENLKGISFGE 421

  Fly   235 FLAFFRFVQDVSIMDNALAFYYFTGADISPKTMRHIAYVVTGVKLSQHLTDVIFCIFDRNNDNII 299
            ..|||.|:..:..:|.||.|:...|..|..|.::.:|..|||:.||.|:.||:..:||.|.|..:
 Worm   422 TKAFFEFLYHIDDVDIALHFHKMAGMSIDAKLLQRVAVKVTGIPLSDHVVDVVITLFDDNLDGKL 486

  Fly   300 QRKEFTD-MRRQWMHPIPLRKNPKLLSKMCIVCKCTWKMLSAWNLREPHPRY 350
            ..:|... |||:....:...::..|......|.:|..:...|    .|.|.|
 Worm   487 SHEEMVAVMRRRMRRGLERPRDTGLFRLFDAVLECGKRAYHA----SPLPFY 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4704	NP_651103.1	EFh_MICU	108..312	CDD:320080	70/225 (31%)
		EF-hand motif	108..137	CDD:320080	8/29 (28%)
		EF-hand motif	147..177	CDD:320080	9/29 (31%)
		EF-hand motif	178..275	CDD:320080	31/101 (31%)
		EF-hand motif	283..312	CDD:320080	10/29 (34%)
micu-1	NP_001255723.1	EFh_MICU	275..494	CDD:320080	67/219 (31%)
		EF-hand motif	275..304	CDD:320080	8/28 (29%)
		EF-hand motif	330..432	CDD:320080	33/102 (32%)
		EF-hand motif	433..462	CDD:320080	8/28 (29%)
		EF-hand motif	470..494	CDD:320080	7/23 (30%)