DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4704 and micu1

DIOPT Version :9

Sequence 1:	NP_001287476.1	Gene:	CG4704 / 42706	FlyBaseID:	FBgn0039029	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_012809601.1	Gene:	micu1 / 100127574	XenbaseID:	XB-GENE-953464	Length:	479	Species:	Xenopus tropicalis

Alignment Length:	374	Identity:	134/374 - (35%)
Similarity:	215/374 - (57%)	Gaps:	33/374 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQYENRLRLHAHPTKIFRYFATIKMKNKSGKWELYMTPNDFLRSIQPGLKQPENLGLDKFQILDE 65
            |:||||:|.::.|.||||||||:|:.::||:.|::|||.||:|||.|..|||||||||:|.|...
Frog   109 MEYENRIRAYSTPDKIFRYFATLKVIHESGESEVFMTPQDFVRSITPNEKQPENLGLDQFIIKRY 173

  Fly    66 HAANKWIPE---------VKDDSIFLKIEKRGLLTYSDYVLLTILLSIPERNVRISFKLFDLNGD 121
            ...:.|..|         ..:||||..:.:.||:::|||:.||.:||.|:||..|:||:||||||
Frog   174 DGKDFWQTEKISQEREKFADEDSIFYSLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGD 238

  Fly   122 GDVTIDELDTVFMAMTQGEVSM-----------------MNSHLKSHFFGHRLNKTLSIDEFLKF 169
            |:|.::|.:.| .::.:.:.||                 .:|.|.::|||..|...|:|..||:|
Frog   239 GEVDMEEFEQV-QSIIRSQTSMGMRHRDRSTTGNTLKTGFSSALTTYFFGADLKGKLTIKNFLEF 302

  Fly   170 LHALHIEIHTDQFQNLLKESSSVISELDFAKVVLGLRKSRSER-REILKRVKKKFGQMDHGITLE 233
            ...|..::...:|:. .......|:|..|..::|.....:|:: ..:||::||:|...: |:|.|
Frog   303 QRKLQHDVLKLEFER-HDPVDGHITERQFGSMLLAYSGVQSKKLTHMLKQLKKRFKDAE-GLTFE 365

  Fly   234 EFLAFFRFVQDVSIMDNALAFYYFTGADISPKTMRHIAYVVTGVKLSQHLTDVIFCIFDRNNDNI 298
            |...||.|:::::.:|.||:||:..||.:...||:.:|..|..|:||.|:.||:|.:||.:.:..
Frog   366 EVENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGE 430

  Fly   299 IQRKEF-TDMRRQWMHPIPLRKNPKLLSKMCIVCKCTWKMLSAWNLREP 346
            :..||| ..|:::.|..:...|:......|..:.||..:  :||:...|
Frog   431 LSNKEFIAIMKQRLMRGLEKPKDMGFTRLMRAMWKCAQE--TAWDFAMP 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4704	NP_001287476.1	EFh	113..171	CDD:298682	25/74 (34%)
CG4704	NP_001287476.1	EF-hand_8	259..307	CDD:290545	18/48 (38%)
micu1	XP_012809601.1	EF-hand_5	226..249	CDD:289945	12/22 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425365at33208
OrthoFinder	1	1.000	-	-		FOG0005802
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12294
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020