|
Fly 352 QLTDRLLQQQH--LQQCQQQQLQ--------------------SLGSSDVEEDLA-AEELSEESL 393
:||...|...| |..||....| .||.:..::||. |:.|...||
Human 6 KLTGETLIVHHIPLVHCQVPDRQCCGGAGGGGGSTRPNPFCPPELGITQPDQDLGQADSLLFSSL 70
Fly 394 KQNVAIVLSNLDRYNNALRS------------IILNEQVSSSIITPSDSLLFGEDSSGLLYCDN- 445
.........::|...:..|. .:|.|.| ||...|.||.|:
Human 71 HSTPGGTARSIDSTKSRSRDGRGPGAPKRHNPFLLQEGV-------------GEPGLGDLYDDSI 122
Fly 446 -DNSRKHK------GNNNFVLGKMAATPESDYNSNATTPGG--RSSEQQLQQQQQQ-------QQ 494
|::.:.. |..||.|......|. ......|.| ||....::.|:|: ||
Human 123 GDSATQQSFHLHGTGQPNFHLSSFQLPPS---GPRVGRPWGTTRSRAGVVEGQEQEPVMTLDTQQ 184
Fly 495 LGVGGML-------------CGGGGGGGVGMRETTNGGGNNLNCSLASSHDFTHDNSDYQWFL-- 544
.|..... |||.||.| :||| .|..|...| |.:|.|
Human 185 CGTSHCCRPELEAETMELDECGGPGGSG-------SGGG----ASDTSGFSF-----DQEWKLSS 233
Fly 545 DYGYRD-GCGGM--QRSVLSSLSASYNAMGDLIYYEDLAKNLDANLAEVDMESFRAEDIHSLLSH 606
|...|: ||.|. |....||.|:...| .|.::..|...|..:.| ..|::.
Human 234 DESPRNPGCSGSGDQHCRCSSTSSQSEA-------------ADQSMGYVSDSSCNSSD-GVLVTF 284
Fly 607 LPAYCKSLGGTNSRLQQSLLLQQQQQQQQQLQQQQVLQHNSMLQHMSQTSTTSTNELIDNSFCKS 671
...|.|..|...:.| ||..|..| |:|||..
Human 285 STLYNKMHGTPRANL------------------------NSAPQSCS-----------DSSFCSH 314
Fly 672 --------ELLFSPVRESHISVDSLDMDAYPDDG--------------EIILTCNKDNYTIAFEG 714
:|..||. ||.:|.:| .:|:.| |:...||.
Human 315 SDPGAFYLDLQPSPF-ESKMSYES----HHPESGGREGGYGCPHASSPELDANCNS--------- 365
Fly 715 SVLYSDDSFYADP----SDIAARNKQNCINLHSNLEDIVKRNKALEVSMSRSAQAFQPLCPMSPK 775
|.. :.:| :|:.| |....:.|. :..:|....|:...|:|: .| ||.
Human 366 ---YRP---HCEPCPAVADLTA-----CFQSQARLV-VATQNYYKLVTCDLSSQS-SP----SPA 413
Fly 776 GQAATTSAAKLQRRSLFLVSPARRYPSG-------NNNTETITITRHLPQCTVRKSSSLPNLQNE 833
|.:.|:.:.:..: :|| |.| :..:|.....: |.:|.|
Human 414 GSSITSCSEEHTK-----ISP----PPGPGPDPGPSQPSEYYLFQK-------------PEVQPE 456
Fly 834 EAMAGSCHKEQGPEESGPQAVPLNVSQAISTSTMEAGKSRSRNL-----------LPMCQMPISI 887
|..|.| ...|.....||..:...|....|...:..|:.|||:. |...:..:|.
Human 457 EQEAVS-SSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSC 520
Fly 888 SVSISERLQQQADQQLPSEQITPTSQQPQQQHHHSHHHRHKHRCSCSQESHISGSASSGNSSNPP 952
.|.:||.....|....|..::|..::..: |...:|.|.:||
Human 521 PVRLSEGPAAMAGPGSPPRRVTSFAELAK------------------------GRKKTGGSGSPP 561
Fly 953 AFNLVKLFI---KQKSSNSSGGQEDLGAQASAHTC-------------MDV----SSGCW----- 992
:::.: .|:.|.....|:|.||.....|| ||: .|..|
Human 562 ----LRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVC 622
Fly 993 --------PSSDAASSSSGSLEQRL-------------------RKKSMNDSGKGSAVSRHDEEE 1030
|.:...::..|.|.|.: |.::.....:...|.|:.:|:
Human 623 QGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQ 687
Fly 1031 --------------HYPDTETPRRQLRARSEAVFYDDVASSSSTGSLTATNSPAHRRRSMPLRNP 1081
|:|......|.|.:.|:.. |....:.|..|| ||..|
Human 688 RPTTLPIQPFVFQHHFPKQLAKARALHSLSQLY---------SLSGCSRTQQPA------PLAAP 737
Fly 1082 QLYQLAAQVS----TGSQMSS----------EASSEQLTQVPR--------RAEAGCGTST---R 1121
||||| :|...:| :|.||..|..|. |:....|.|| .
Human 738 -----AAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSA 797
Fly 1122 PLSCASSSEMITRS-----MQTSCGSLSTTRSSLSDRYRCVPPSFLEKLNNLGEERQAPIYVIYP 1181
..||:...|..|.: ...||. |..|.:.|.: |....:|:..|.| |.::.
Human 798 STSCSPPPEQPTATESLPPWSHSCP--SAVRPATSQQ----PQKEDQKILTLTE------YRLHG 850
Fly 1182 NYALPDLGFVKTNASTDVIFSPFNYKMTMDGATGSTSSSGSLRKQRNSSQSVSEDEILKTLDYKH 1246
..:||.||..::..|. ...:...|..||.:: |.|:.:....:.||
Human 851 TGSLPPLGSWRSGLSR-------AESLARGGGEGSMAT-------RPSNANHLSPQALK------ 895
Fly 1247 VADWQSLATLLPSEYRRR-----------LQHIPEVKHLVRQLDAELSQR-PLFCMSPPLRRNRT 1299
|: ||||: |.. |..:|.|::| |:| ..|......:
Human 896 ---WR--------EYRRKNPLGPPGLSGSLDR--------RSQEARLARRNPIF-EFPGSLSAAS 940
Fly 1300 HICDC-------------AKYFQGQQTQTDE------ASSSGSSQQPSSGYRGSSTLLTDSELDV 1345
|: :| ...||...:.|:: .|..|||:..|........|:....:.|
Human 941 HL-NCRLNGQAVKPLPLTCPDFQDPFSLTEKPPAEFCLSPDGSSEAISIDLLQKKGLVKAVNIAV 1004
Fly 1346 DPLKQMYVYQYDQQRMDSGVETSPGSQLTQTPPQ----------PMPRSILRKAHSA-------- 1392
| :.|..:...| |.||:...|: :...|. |..|::|.....|
Human 1005 D----LIVAHFGTSR-DPGVKAKLGN--SSVSPNVGHLVLKYLCPAVRAVLEDGLKAFVLDVIIG 1062
Fly 1393 QSRSKRNSMIEA------------------QQTQKLTKLEKR-----------RSLQ-------- 1420
|.::...|::|| .|..:||....| |||:
Human 1063 QRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYN 1127
Fly 1421 ---------EPPNNYGL---------GSTDEL-------------ADVFEEEEHSQPAPPVKQ-- 1452
:| :|. |..:|| .|:..:....|.....:|
Human 1128 HEDIIQTHYQP---WGFLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGQQQRQHK 1189
Fly 1453 RLSRKDLD-----------ARARAESFLASLPRS----------------------ELKYYAEIA 1484
.|.|...| ||||.:.....:.|: |.:..||.|
Human 1190 ELLRVSQDLLLSAHSTLQLARARGQEGPGDVDRAAQGERVKGVGASEGGEEEEEEEETEEVAEAA 1254
Fly 1485 ------------------SILESSGEHV--TYDAAALKKEVSRVLSQQKKVSFNDEGVAAGLQQH 1529
.:::||..:: :.:.:...:..|...|::|| |...|
Human 1255 GGSGRARWARGGQAGWWYQLMQSSQVYIDGSIEGSRFPRGSSNSSSEKKK------GAGGG---- 1309
Fly 1530 AKRFATPPNSPNISMGALKRDTVDVLEQRKIESNRFKRLQIQWE--LMSKDSSMLKEL------- 1585
.||.:|....|.::........:..:...| .|. :.|...|:|.||
Human 1310 -----GPPQAPPPREGVVEGAEACPASEEALGRER------GWPFWMGSPPDSVLAELRRSRERE 1363
Fly 1586 ---ASEAATKSGGSTPTS-----GNSTGSNSA-----PRSRIP-----------RPVSYPAG--R 1624
||.|..:.|.|.|:. |:..||..| |.:|:| :.|:...| |
Human 1364 GPAASPAENEEGASEPSPGGIKWGHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRR 1428
Fly 1625 SSTPTSSRTAPVLATPSPARPATPKTVTKS--HN---KPGLFTSPRPSRLTSAQEAAGGNKVSTR 1684
...|..|...| .|||.|::|....:: |: .||..:..:...|.....|.|.....:|
Human 1429 EPEPKESLQEP----HSPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSR 1489
Fly 1685 SPSRIVQPKRYSLAGATTPT-STTPTSAR 1712
.|...:.|..|. ..||| |.||.|::
Human 1490 GPDSGLVPLAYV---TLTPTPSPTPGSSQ 1515
| 
