DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp12-46 and UBP4

DIOPT Version :9

Sequence 1:	NP_651099.1	Gene:	Usp12-46 / 42702	FlyBaseID:	FBgn0039025	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_565532.1	Gene:	UBP4 / 816763	AraportID:	AT2G22310	Length:	365	Species:	Arabidopsis thaliana

Alignment Length:	423	Identity:	217/423 - (51%)
Similarity:	277/423 - (65%)	Gaps:	65/423 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGANVSQLEREIGSDLFPPNEHYFGLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKR-PKE 64
            |||..|:||:.:| |.||..|.|||..|||||||.||||||||||.||||::||:.|.||. .:|
plant     1 MGAAGSKLEKALG-DQFPEGERYFGFENFGNTCYCNSVLQALYFCAPFREQLLEHYANNKADAEE 64

  Fly    65 TLLSCLADLFYSIATQKKKVGSIAPKKFITRLRKEKEEFDNYMQQDAHEFLNFLINHINEIILAE 129
            .||:||||||..|::||||.|.||||:|:.||:|:.|.|.:||.||||||||:|:|.:.||:..|
plant    65 NLLTCLADLFSQISSQKKKTGVIAPKRFVQRLKKQNELFRSYMHQDAHEFLNYLLNELVEILEKE 129

  Fly   130 RNAGPSNGNPKATNQGGSTSAMASSIASKSSSTSNSNSNSNSTTNSNGNSSNSTGSLNANTSVLD 194
            ..|      .||.|:   ||:....||                                  :||.
plant   130 TQA------TKADNE---TSSSPEKIA----------------------------------NVLK 151

  Fly   195 ASGSLTATTTPIISGNGTGTNGANSEP--TWVHEIFQGILTSETRCLNCETVSSKDENFFDLQVD 257
            |         |:       .||.:.||  ||||:|||||||:|||||.||||:::||.|.||.:|
plant   152 A---------PL-------ANGVHKEPIVTWVHKIFQGILTNETRCLRCETVTARDETFLDLSLD 200

  Fly   258 VDQNTSITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILALHLKRFKYMEQFNR 322
            ::||:|||.||:.||:||||.:::||.||.|||.|||||||::||.|.||.:||||||||||..|
plant   201 IEQNSSITSCLKNFSSTETLHAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKYMEQLGR 265

  Fly   323 HIKVSHRVVFPLELRLFNTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKSHGLWLLFDDDM 387
            :.|:|:||||||||:|.||.|:.|  |..|.|.|||:|.|||||.|||:|:||||..||.|||:.
plant   266 YKKLSYRVVFPLELKLSNTVDEYV--DIEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDDES 328

  Fly   388 VDKIEASTIEDFYGLTSDIHKSSETGYILFYQS 420
            |:.||.|.::.|:|.:.:...:::.||||.|:|
plant   329 VEIIEESAVQTFFGSSQEYSSNTDHGYILLYES 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	202/396 (51%)
UBP4	NP_565532.1	Peptidase_C19G	24..360	CDD:239128	202/396 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	375	1.000	Domainoid score	I172
eggNOG	1	0.900	-	-		E1_KOG1864
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56957
Inparanoid	1	1.050	396	1.000	Inparanoid score	I481
OMA	1	1.010	-	-		QHG54027
OrthoDB	1	1.010	-	-		D378361at2759
OrthoFinder	1	1.000	-	-		FOG0001354
OrthoInspector	1	1.000	-	-		otm2926
orthoMCL	1	0.900	-	-		OOG6_101733
Panther	1	1.100	-	-	O	PTHR24006
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X844
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840