Protein Alignment Usp12-46 and Usp42

DIOPT Version :10

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_084025.2
• Gene: Usp42 / 76800
• MGIID: 1924050
• Length: 1324
• Species: Mus musculus
• Alignment Length: 444
• Identity: 104/444 - (23%)
• Similarity: 167/444 - (37%)
• Gaps: 138/444 - (31%)

  Fly     9 EREIGSDLFPPNEHYF-----------------GLVNFGNTCYSNSVLQALYFCKPFREKVLEYK 56
            ::.:|..:.||.:..|                 ||.|.||||::|:.||.|.:..|....:|.:
Mouse    78 DQVLGDGIAPPQKVLFPSEKICLKWQQSHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSH- 141

  Fly    57 AKNKRPKETLLSCLADLFYSIATQKKKVGS--------IAPKKFITRLRKEKEEFDNYMQQDAHE 113
                   |...:|.|:.|..:.|.:..:..        |.|...|..:|:....|....|:||||
Mouse   142 -------EHSKTCHAEGFCMMCTMQTHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHE 199

  Fly   114 FLNFLINHINEIILAERNAGPSNGNPKATNQGGSTSAMASSIASKSSSTSNSNSNSNSTTNSNGN 178
            ||.:.::.:.:..|
Mouse   200 FLQYTVDAMQKACL--------------------------------------------------- 213

  Fly   179 SSNSTGSLNANTSVLDASGSLTATTTPIISGNGTGTNGANSEPTWVHEIFQGILTSETRCLNCET 243
              |.:..|:.:|.         |||.                   |.:||.|.|.|..:||||:.
Mouse   214 --NGSNKLDRHTQ---------ATTL-------------------VCQIFGGYLRSRVKCLNCKG 248

  Fly   244 VSSKDENFFDLQVDVDQNTSITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILA 308
            ||...:.:.|:.:::....|:|..|..|...|.|..:|.:||..|.....|.||..:.:...:|.
Mouse   249 VSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLT 313

  Fly   309 LHLKRFKYMEQFNRHIKVSHRVVFP--LELRLFNTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYI 371
            :.||||   ..|... |::..|.:|  |::|.:.:..:  ....:|.|.||::|.|...:.|||.
Mouse   314 ISLKRF---ANFTGG-KIAKDVKYPEYLDIRPYMSQPN--GEPIIYVLYAVLVHTGFNCHAGHYF 372

  Fly   372 SIVK-SHGLWLLFDDDMVDKIEASTIEDFYGLTSDIHK-SSETGYILFY-QSRD 422
            ..:| |:|||...:|.:|.             ||||.. .::..|:||| :|.|
Mouse   373 CYIKASNGLWYQMNDSIVS-------------TSDIRAVLNQQAYVLFYIRSHD 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	98/406 (24%)
Usp42	NP_084025.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..86		1/7 (14%)
		Peptidase_C19E	109..409	CDD:239126	97/407 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	417..517
		Herpes_BLLF1	<420..795	CDD:282904
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	549..587
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	624..676
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	717..780
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	816..847
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	880..1026
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1145..1262
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1303..1324