Protein Alignment Usp12-46 and Usp46

DIOPT Version :10

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_808229.1
• Gene: Usp46 / 69727
• MGIID: 1916977
• Length: 366
• Species: Mus musculus
• Alignment Length: 422
• Identity: 267/422 - (63%)
• Similarity: 303/422 - (71%)
• Gaps: 67/422 - (15%)

  Fly     1 MGANVSQLEREIGSDLFPPNEHYFGLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRPKET 65
            ||.|.|.||::||.:.||.|||||||||||||||.||||||||||:||||.||.|||:.|: ||.
Mouse    12 MGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKK-KEN 75

  Fly    66 LLSCLADLFYSIATQKKKVGSIAPKKFITRLRKEKEEFDNYMQQDAHEFLNFLINHINEIILAER 130
            ||:||||||:||||||||||.|.|||||:|||||.:.||||||||||||||:|:|.|.:|:..|:
Mouse    76 LLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEK 140

  Fly   131 NAGPSNGNPKATNQGGSTSAMASSIASKSSSTSNSNSNSNSTTNSNGNSSNSTGSLNANTSVLDA 195
            .....||..|                         |.|.|....:|
Mouse   141 KQEKQNGKLK-------------------------NGNMNEPAENN------------------- 161

  Fly   196 SGSLTATTTPIISGNGTGTNGANSEPTWVHEIFQGILTSETRCLNCETVSSKDENFFDLQVDVDQ 260
                                  ..|.|||||||||.||:|||||||||||||||:|.||.|||:|
Mouse   162 ----------------------KPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQ 204

  Fly   261 NTSITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILALHLKRFKYMEQFNRHIK 325
            |||||||||.|||||||||:.|:.|:.|||.||||||||||||||||||||||||||||.:|:.|
Mouse   205 NTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTK 269

  Fly   326 VSHRVVFPLELRLFNTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKSHGLWLLFDDDMVDK 390
            :|:||||||||||||||.||||.||:|||.|||:||||||||||||:||||||.|||||||:|:|
Mouse   270 LSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEK 334

  Fly   391 IEASTIEDFYGLTSDIHKSSETGYILFYQSRD 422
            |:|..||:||||||||.|:||:|||||||||:
Mouse   335 IDAQAIEEFYGLTSDISKNSESGYILFYQSRE 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	248/393 (63%)
Usp46	NP_808229.1	Peptidase_C19G	36..363	CDD:239128	248/393 (63%)