Protein Alignment Usp12-46 and Usp30

DIOPT Version :10

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_572274.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Alignment Length: 554
• Identity: 115/554 - (20%)
• Similarity: 183/554 - (33%)
• Gaps: 182/554 - (32%)

  Fly    13 GSDLFPPNEHYFGLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRPKETLLSCLADLF--- 74
            ||.|........||.|||.||:.|::|||:..|..|...:..|...:...|..:.|.|..|.
  Fly    28 GSRLRQRRGQIAGLHNFGLTCFLNTLLQAMAACPQFIAWLQLYNNASPDRKSLITSMLNTLEVVN 92

  Fly    75 ----------YS---IATQKKKVGSIAPKKFITRLRKEKEEFDNYMQQDAHEFLNFLINHINEII 126
                      ||   :......:|.:.|::                :.||||..:.|:..:.|..
  Fly    93 GTHATLRGDPYSPGAVLRALNALGWVIPQE----------------EHDAHELFHVLLTCLEEEA 141

  Fly   127 LAERNAG------PSNGNPK------ATNQGG--STSAMASSIASKSSSTSNSNSNSNS------ 171
            :..:..|      |::.:..      ||..||  |.|:||:.:.:........|..|::
  Fly   142 IRPQPLGCLSDALPTDNDDNSSLAGTATPVGGFRSFSSMAAGLGASQRIGDQPNRPSSAMLTDFL 206

  Fly   172 -------------------TTNSNGNSSNSTGSLNANTSVLDASGSLTATTTPIIS--------- 208
                               |.:|..:.....|:....:.:|||....|....|::|
  Fly   207 NMEYDESTSLQRLVRSEAHTPDSPASVCERDGNDRLGSVLLDAVSPGTPFGFPLVSNPDSLATPM 271

  Fly   209 --------------------------------------GNGTGTNGANSEPTWVHEIFQGILTSE 235
                                                  |.|..:..:|..|:.|...|||.:.::
  Fly   272 LGGERSSRPRLPQSQQQQDEGLNRRVSSSCRSLERLHRGPGRVSIWSNMMPSQVAHPFQGAMGAQ 336

  Fly   236 TRCLNCETVSSKDENFFD---LQVDVDQNT--SITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQ 295
            ..|..|.:.|:...:.||   |.:...:.|  |:.|.|..:..:|.| ||  .|||:|.......
  Fly   337 IVCNGCGSKSAVRYDKFDSITLNLPPQRRTGLSLGHLLSEYITSEDL-SD--VKCDSCNETTTHT 398

  Fly   296 KRMRVKKLPMILALHLKRFKYMEQFNRHIKVSHRVVFPLEL------------------------ 336
            |.:...|||..|.:|:.|..::.. .:..|....|.||..|
  Fly   399 KSVTFAKLPACLCIHVARTVWLPT-GQVCKRKDYVHFPESLSMAPYSFVQPHLNSQAGTPWGSTM 462

  Fly   337 RLFNTSDDAVN------------PDRLYDLTAVVIHCGSGPNRGHYI-----SIVKSHGLWLLFD 384
            .|:::|....|            |..||.|.|||:|.|.. |.||::     |:..:| .|....
  Fly   463 SLYSSSLPMNNGVGGGEGFGTMFPKNLYRLLAVVVHSGEA-NSGHFVTYRRGSLRNAH-RWYYTS 525

  Fly   385 DDMVDKIEASTIEDFYGLTSDIHKSSETGYILFY 418
            |.:|.::....:            .|...|:|||
  Fly   526 DTIVREVSIDEV------------LSVPAYLLFY 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	112/542 (21%)
Usp30	NP_572274.1	Peptidase_C19	39..>139	CDD:470612	27/115 (23%)
		Peptidase_C19F	<323..548	CDD:239127	59/243 (24%)