Protein Alignment Usp12-46 and Usp1

DIOPT Version :9

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001015015.1
• Gene: Usp1 / 313387
• RGDID: 1306461
• Length: 784
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 123/542 - (22%)
• Similarity: 194/542 - (35%)
• Gaps: 175/542 - (32%)

  Fly     3 ANVSQLEREIGSDLFPPNEHYFGLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRPKETLL 67
            |..|.:..|...:|.|    :.||.|.|||||.||:||.||||..|:..|........|.||.|.
  Rat    64 AQSSPVSCEKRENLLP----FVGLNNLGNTCYLNSILQVLYFCPGFKAGVKHLFNIISRKKEALK 124

  Fly    68 ---------SCLADLFYS---------------------IATQKKKVGSIA--PKKFITRLRKEK 100
                     ||..|...|                     :...:|....:|  |::.:..||:..
  Rat   125 DDSIQKDKGSCKEDPLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELN 189

  Fly   101 EEFDNYMQQDAHEFLNFLINHINEI-----------------------ILAERNAGPSN------ 136
            ..::.|:|.||.|.|..::.:|.|.                       :..|...|.|:
  Rat   190 PMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEIKNLTEFSSKVEEKSLQKEETGGISSTETDST 254

  Fly   137 ------------GNPKATNQG--------------------------------GSTSAMASSIAS 157
                        ||.|..:.|                                |.|...:..|..
  Rat   255 RNLDDLKEQLPKGNWKRKSDGESGNMKKKVKLSRESQPLEENQRQTRSKRKATGDTLEASPKIIP 319

  Fly   158 KSSSTSNSNSNSNS----------------------------TTN--SNGNSSNSTGSL------ 186
            |..|.:.|...|..                            |||  |.|....:.|.|
  Rat   320 KCVSENESAKPSQKKSKVKINWLKPATKQPSILSKFCSLGKITTNQRSKGQPKVNEGDLEEDLEK 384

  Fly   187 NANTSVLDASG--SLTATTTPIISGNGTGTNGANSEPTW--VHEIFQGILTSETRCLNCETVSSK 247
            :...:.::.||  |..::.||:.|......|....:..:  |.::|||.|...||||.||:::.:
  Rat   385 DGRDNTVNGSGPASPGSSVTPVDSSEAKSINKGAEQIGFELVEKLFQGQLVLRTRCLECESLTER 449

  Fly   248 DENFFDLQVDVDQN-------------------TSITHCLRCFSNTETLCSDNKFKCDNCCSYQE 293
            .|:|.|:.|.|.::                   .::...:..|::.|.:..::|:.|:||..|.|
  Rat   450 REDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTE 514

  Fly   294 AQKRMRVKKLPMILALHLKRFKYME-QFNRH----IKVSHRVVFPLELRLFNTSDDAVNPDRLYD 353
            |::.:...|:|.::.:|||.|.... :|:.:    .|::..::.||:|.|...|....|..  |.
  Rat   515 AERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDS--YG 577

  Fly   354 LTAVVIHCGSGPNRGHYISIVK 375
            |.|||:|.|...:.|||.:.||
  Rat   578 LFAVVMHSGITISSGHYTASVK 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	118/520 (23%)
Usp1	NP_001015015.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..54
		Peptidase_C19	82..>253	CDD:271592	42/170 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	232..341		14/108 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	363..411		12/47 (26%)
		Peptidase_C19O	<424..599	CDD:239136	49/176 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	686..723

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1864
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24006
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000