Protein Alignment Usp12-46 and Usp38

DIOPT Version :10

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001100888.2
• Gene: Usp38 / 307764
• RGDID: 1311974
• Length: 1041
• Species: Rattus norvegicus
• Alignment Length: 573
• Identity: 131/573 - (22%)
• Similarity: 191/573 - (33%)
• Gaps: 244/573 - (42%)

  Fly    25 GLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRPKETLLSCLADLFYSIA-TQKKKVGSIA 88
            ||:|.|||||.|||||||:....||.:||   :.|.....:|:..|..||..:| ||::   :.|
  Rat   446 GLINLGNTCYMNSVLQALFMATEFRRQVL---SLNLNGCNSLMKKLQHLFAFLAHTQRE---AYA 504

  Fly    89 PKKFITRLRKEKEEFDNYMQQDAHEFLNFLINHINE---IILAERNAGPSNGNPKATNQGGSTSA 150
            |:.|....|  ...|....|||..|:|.||::.::|   |:..:.:..||.|.       |.|..
  Rat   505 PRIFFEASR--PPWFTPRSQQDCSEYLRFLLDRLHEEEKILRIQSSHKPSEGL-------GCTET 560

  Fly   151 MASSIASKSSSTSNSNSNSNSTTNSNGNSSNSTGSLNANTSVLDASGSLTATTTPIISGNGTGTN 215
            ....:.:|.:..|.|.|                                            ||
  Rat   561 CLQEVTNKVAVPSESPS--------------------------------------------TG-- 579

  Fly   216 GANSEPTWVHEIFQGILTSETRCLNCETVSSKDENFFDLQV------------------------ 256
              .||.|.:.::|.|.|.:...||||.:.|.|.|.|.||.:
  Rat   580 --GSEKTLIEKMFGGKLRTHICCLNCRSTSHKVEAFTDLSLAFCPSPSVEDSSFQDPASLPSAQD 642

  Fly   257 --------------------------------------------------------------DVD 259
                                                                          ||.
  Rat   643 DGLMQTSVTDAEEEPVVCNPAAAAFVCDSVVNERRLGSPPVEFPCAKNSSVPGESAKILVSKDVP 707

  Fly   260 QN------TSITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILALHLKRFKYME 318
            ||      ||:|..|..|...|.|..:|::.|::|.|.|.|:|.|::.:.|..|.|.|.||.|.:
  Rat   708 QNPGGESTTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTMQITEEPEYLILTLLRFSYDQ 772

  Fly   319 QFNRHIKVSHRVVFP--LELRLFNTS------------------------------DDAVNPDRL 351
            :::...|:...|..|  |||.:..||                              ::|..|..:
  Rat   773 KYHVRRKILDNVSLPLVLELPVKRTSLSSLSEGWSADADFTDVNENLAKKLKPSGTEEAFCPKLV 837

  Fly   352 -YDLTAVVIHCGSGPNRGHYISIVK--------------SHGL---------------------- 379
             |.|::||:|.|.....|||.|..:              |..|
  Rat   838 PYLLSSVVVHSGVSSESGHYYSYARNITGTESSYQMRPQSESLSLTPSQSSLLGGESPNTVIEQD 902

  Fly   380 ---------WLLFDDDMVDKIEASTIEDFYGLTSDIHKSSETGYILFY--QSR 421
                     |.||:|   .::..::.:....:||...|  :|.|:|||  |||
  Rat   903 LENKEMSQEWFLFND---SRVTFTSFQSVQKITSRFPK--DTAYVLFYKKQSR 950

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	128/569 (22%)
Usp38	NP_001100888.2	Peptidase_C19H	446..946	CDD:239129	127/567 (22%)