Protein Alignment Usp12-46 and Usp35

DIOPT Version :10

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_006507886.1
• Gene: Usp35 / 244144
• MGIID: 2685339
• Length: 1072
• Species: Mus musculus
• Alignment Length: 561
• Identity: 109/561 - (19%)
• Similarity: 171/561 - (30%)
• Gaps: 248/561 - (44%)

  Fly    25 GLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRPKETLLSCLADLFYSIATQKKKVGSIAP 89
            ||:|.|||||.|||||||:....||..||.....|.:|   |::.|..||..:...::.  :|:|
Mouse   505 GLINLGNTCYVNSVLQALFMASDFRHCVLRLTENNSQP---LMTKLQWLFAFLEHSQRP--AISP 564

  Fly    90 KKFITRLRKEKEEFDNYMQQDAHEFLNFLINHINEIILAERNAGPSNGNPKATNQGGSTSAMASS 154
            :.|::  ......|....|||..|:|.:|::.::|              .:.|..........||
Mouse   565 ENFLS--ASWTPWFSPGTQQDCSEYLKYLLDRLHE--------------EEKTGMRICQKLKQSS 613

  Fly   155 IASKSSSTSNSNSNSNSTTNSNGNSSNSTGSLNANTSVLDASGSLTATTTPIISGNGTGTNGANS 219
            :.|......:||:.|
Mouse   614 LPSPQEELPSSNATS-------------------------------------------------- 628

  Fly   220 EPTWVHEIFQGILTSETRCLNCETVSSKDENFFDLQV---------------------DV----- 258
                |.::|.|.:.:...||:|..|||::|.|.||.:                     ||
Mouse   629 ----VEKMFGGKIVTRICCLHCLNVSSREEAFTDLSLAFPPPERSRHRRLGSVMLPTEDVRVQEL 689

  Fly   259 ----------------------------------------------------------------- 258
                                                                             
Mouse   690 TLAPRAPGAQRQRKRCITGDAPRTGLDSEGVDTIGTGGRSGQEKVEREQAGKEKEVAEDREEEGT 754

  Fly   259 --------------------------------------------------------DQNTSITHC 267
                                                                    :.:.|:...
Mouse   755 REEEKEEGEEKDKEKEKKEDEKEKEAENGKEKEGDSLGPGTHREAATPPREQTCGPEGSRSVLDL 819

  Fly   268 LRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILALHLKRFKYMEQFNRHIKVSHRVVF 332
            :..|.:.|.|.::|::.|::|.|.|:|:|.:.:.:.|..|.|.|.||.:..:..|..|:...|..
Mouse   820 VNYFLSPERLTAENRYYCESCASLQDAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVTI 884

  Fly   333 PLELRLFNTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKS-----------------HGLW 380
            ||.|||    ..|....:.|||.:||:|.|.....|||....:.                 ...|
Mouse   885 PLLLRL----PLAGGQGQAYDLCSVVVHSGVSSESGHYYCYAREGAARPAPVLGSTERPEPENQW 945

  Fly   381 LLFDDDMVDKIEASTIEDFYGLTSDIHKSSETGYILFYQSR 421
            .||:|   .::..|:.|....:||...|  :|.|:|||:.|
Mouse   946 YLFND---TRVSYSSFESVSNVTSFFPK--DTAYVLFYRQR 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	107/557 (19%)
Usp35	XP_006507886.1	Peptidase_C19	505..979	CDD:470612	107/557 (19%)