Protein Alignment Usp12-46 and Usp1

DIOPT Version :9

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001288343.1
• Gene: Usp1 / 230484
• MGIID: 2385198
• Length: 784
• Species: Mus musculus
• Alignment Length: 541
• Identity: 127/541 - (23%)
• Similarity: 193/541 - (35%)
• Gaps: 174/541 - (32%)

  Fly     3 ANVSQLEREIGSDLFPPNEHYFGLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRPKETL- 66
            |..|.:..|...:|.|    :.||.|.|||||.||:||.||||..|:..|........|.||.|
Mouse    64 AQSSPVSCEKRENLLP----FVGLNNLGNTCYLNSILQVLYFCPGFKTGVKHLFNIISRKKEALK 124

  Fly    67 --------------------LSC-LADLFYSI--------ATQKKKVGSIA--PKKFITRLRKEK 100
                                |.| |..|..|:        ...:|....:|  |::.:..||:..
Mouse   125 DDSNQKDKGSCKEESLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELN 189

  Fly   101 EEFDNYMQQDAHEFLNFLINHINEII----------LAE-------------------------- 129
            ..::.::|.||.|.|..::.:|.|..          |||
Mouse   190 PMYEGFLQHDAQEVLQCILGNIQETCQLLKKEEIKNLAELSGKVEEQSLQKEETGGITSTEIDSM 254

  Fly   130 ---------------------------------RNAGPSNGNPKATNQG----GSTSAMASSIAS 157
                                             |.:.|...|.:.|...    |.|...|..|..
Mouse   255 RNTEDVKEQLPKGNWKRKSDSESSNVKKKVKLSRESQPLEENQRQTRSKRKAIGDTLEAAPKIIP 319

  Fly   158 KSSSTSNSNSNSNS----------------------------TTN--SNGNSSNSTGSLNANT-- 190
            |..|.|.|...|..                            |||  |.|......|.:..:.
Mouse   320 KCVSESESAKPSQKKSKVKINWLKPSTKQPSILSKFCSLGKITTNQRSKGQPKEKEGDVEEDLEK 384

  Fly   191 --SVLDASG---SLTATTTPIISGNG-TGTNGANSEP-TWVHEIFQGILTSETRCLNCETVSSKD 248
              |...|:|   |..::.||:.|... :|..||.... ..|.::|||.|...||||.||:::.:.
Mouse   385 YGSDHTANGGPESPGSSVTPVDSSEAKSGNKGAEQIGFELVEKLFQGQLVLRTRCLECESLTERR 449

  Fly   249 ENFFDLQVDVDQN-------------------TSITHCLRCFSNTETLCSDNKFKCDNCCSYQEA 294
            |:|.|:.|.|.::                   .::...:..|::.|.:..::|:.|:||..|.||
Mouse   450 EDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEA 514

  Fly   295 QKRMRVKKLPMILALHLKRFKYME-QFNRH----IKVSHRVVFPLELRLFNTSDDAVNPDRLYDL 354
            ::.:...|:|.::.:|||.|.... :|:.:    .|::..::.||:|.|...|....|..  |.|
Mouse   515 ERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDS--YGL 577

  Fly   355 TAVVIHCGSGPNRGHYISIVK 375
            .|||:|.|...:.|||.:.||
Mouse   578 FAVVMHSGITISSGHYTASVK 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	122/519 (24%)
Usp1	NP_001288343.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..56
		Peptidase_C19	82..>253	CDD:271592	42/170 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	233..342		13/108 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	362..414		13/51 (25%)
		Peptidase_C19O	<423..598	CDD:239136	49/176 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	684..725

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1864
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24006
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000