Protein Alignment Usp12-46 and duo-1

DIOPT Version :9

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_505931.3
• Gene: duo-1 / 179586
• WormBaseID: WBGene00001110
• Length: 877
• Species: Caenorhabditis elegans
• Alignment Length: 655
• Identity: 129/655 - (19%)
• Similarity: 199/655 - (30%)
• Gaps: 282/655 - (43%)

  Fly    12 IGSDLFPPNEH-YFGLVNFGNTCYSNSVLQALYFCKP------------------FREKVLEYKA 57
            :.||:|....| ...|||.||:||.||.:||:..|.|                  |.:.:...:|
 Worm   256 LSSDVFLRKLHENRQLVNTGNSCYYNSTMQAVSSCNPLVIRCEQLYRMVRDNIELFDDSMNNDQA 320

  Fly    58 KNKRPKETL------LSCLADLF-------------YSIATQKKKVGSIAPKKFITRLRKEKEEF 103
            ..||....|      :.||...|             |.:...::.||.|            .|||
 Worm   321 DIKRKYIVLQNFLKVVICLGWHFNKRNEGKSIELRRYDLLQYRQNVGKI------------NEEF 373

  Fly   104 DNYMQQDAHEFLNFLINHINEII-LAERNA---------------------------GPSNGNPK 140
            :|..||||||||..||..:::.: :..:|.                           |.||...|
 Worm   374 NNDDQQDAHEFLLTLIGAVDDAMGVMSKNVKTIDNVGITLNPARAFKIDVETMYVCQGCSNEELK 438

  Fly   141 ATNQ---------GGSTSAMASSIASKSSSTSNSNSNSNSTTNSNGNSSNSTGSLNANTSVLDAS 196
            ..::         |.|...:.||....|......:|..:..::|....|.....|..|....:..
 Worm   439 VDSRNDLGVSVMDGCSVQKLVSSFVKWSPIEKECSSCKHKISSSCERISTFPECLIINLKRYELE 503

  Fly   197 G-----SLTATTTPI-------ISGNGTGTNGANSEPTWVHEIFQGILTSETRCLNCE-----TV 244
            |     |:...:..:       :|..|      |..|....|:|:....|.|..:|.|     .:
 Worm   504 GQGPPFSMKKKSCRVEPSFKLDVSSLG------NFPPVEHPEMFENKEYSTTEPVNSEDSRLAEI 562

  Fly   245 SSKDENFFDLQVD------VDQNTSITHC--------------LRCFSNTETLCSD--NKFKCDN 287
            ::.|.:|.|.:|.      .|:..|  .|              ...|||.:.. .|  ::...:|
 Worm   563 TTDDAHFNDSRVSGRLLGGADEEMS--QCSVIVEDVKKRKELYFNIFSNEKDF-DDILDEMGINN 624

  Fly   288 CCSYQEAQKRMRVKK-------------LP----------------------------MI----L 307
                .|.|||...::             ||                            ||    :
 Worm   625 ----GENQKRFHFERHITGPPSKMYQFQLPGATRGITPDGNCFYRAISWWITGVQSHHMIFREAV 685

  Fly   308 ALHLKR----FK----------------------------------------------------- 315
            ..|||:    ||
 Worm   686 GKHLKKNELMFKKYCHNEIYEKYVENAMRDGVWATTCEIFAMANMLNVEIITYLGDSGWVPHSPQ 750

  Fly   316 ----------YMEQFNRHIK--VSHRVVFP--LELRLFNTSDDAVNPDRL--------------Y 352
                      |::..|.|.:  .|.|...|  ..::..||:..::: |.|              |
 Worm   751 NNYPPRKGAIYLKNTNMHYEPTTSLRKNSPERSPMKKENTNGSSMH-DELDENDYLKSDIHPGTY 814

  Fly   353 DLTAVVIHCGSGPNRGHYISIVK---SHGLWLLFDDDMVDKIEASTIEDFYGLTSDIHKSSETGY 414
            .|.|||.|.|..||:|||::..|   .:..||...||.:..:..:.:       |:..:||  ||
 Worm   815 SLVAVVCHLGDSPNKGHYVAYTKELYKNSSWLRCSDDNIYAVSKNDV-------SEAIRSS--GY 870

  Fly   415 ILFYQ 419
            ::||:
 Worm   871 LMFYE 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	124/639 (19%)
duo-1	NP_505931.3	Peptidase_C19Q	270..875	CDD:239138	124/639 (19%)
		OTU	657..>743	CDD:303090	7/85 (8%)
		Peptidase_C19	<750..861	CDD:271592	27/111 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1864
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900