Protein Alignment Usp12-46 and usp-46

DIOPT Version :9

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_499162.2
• Gene: usp-46 / 176381
• WormBaseID: WBGene00011216
• Length: 426
• Species: Caenorhabditis elegans
• Alignment Length: 450
• Identity: 241/450 - (53%)
• Similarity: 306/450 - (68%)
• Gaps: 67/450 - (14%)

  Fly     1 MGA-NVSQLEREIGS--DLFPPNEHYFGLVNFGNTCYSNSVLQALYFCKPFREKVLEYK---AKN 59
            ||| ..||||:||.:  .:...||||:||||||||||.|||:|||:||:|||||||.||   .|:
 Worm     1 MGATGSSQLEKEISTTESVNNANEHYYGLVNFGNTCYCNSVIQALFFCRPFREKVLNYKQTLKKS 65

  Fly    60 KRPKETLLSCLADLFYSIATQKKKVGSIAPKKFITRLRKEKEEFDNYMQQDAHEFLNFLINHINE 124
            ...|:.|::||||||:|||:||::||:||||:|||:|:||.|.||||||||||||.|:|||.|:|
 Worm    66 GASKDNLVTCLADLFHSIASQKRRVGTIAPKRFITKLKKENELFDNYMQQDAHEFFNYLINTISE 130

  Fly   125 II----LAERNAGPSNGNPKATNQGGSTSAMASSIAS--KSSSTSNSNSNSNSTTNSNG--NSSN 181
            .:    :|||.....:|..|   :|..|..:|.:.|.  :|.....|..|...|...|.  |.|:
 Worm   131 TLIQEKIAEREKASRHGTLK---KGNVTVNLAPATAGLPRSDEKGTSERNGGITVEGNEFLNKSD 192

  Fly   182 STGSLNANTSVLDASGSLTATTTPIISGNGTGTNGANSEPTWVHEIFQGILTSETRCLNCETVSS 246
            :|                                      ||:|||||||||:|||||:||||||
 Worm   193 TT--------------------------------------TWIHEIFQGILTNETRCLSCETVSS 219

  Fly   247 KDENFFDLQVDVDQNTSITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILALHL 311
            |||:|.||.:||:|||||:||||.||.|||||.|.|:.|:.|.|.||||||||:||.|.:|||||
 Worm   220 KDEDFLDLSIDVEQNTSISHCLRVFSETETLCGDQKYFCETCSSKQEAQKRMRIKKPPQLLALHL 284

  Fly   312 KRFKYMEQFNRHIKVSHRVVFPLELRLFNTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKS 376
            ||||::|..|||.|:|:||||||||||||.||||...||:|||.|.|:|||:.|||||||::|||
 Worm   285 KRFKFVEPLNRHTKLSYRVVFPLELRLFNVSDDAEYGDRMYDLVATVVHCGATPNRGHYITLVKS 349

  Fly   377 HGLWLLFDDDMVDKIEASTIEDFYGLTSDIH------------KSSETGYILFYQSRDCA 424
            :..||:||||:|:|:|.|::|:|.|:::|.:            |:||:.||||||:||.|
 Worm   350 NSFWLVFDDDIVEKLEVSSMEEFSGMSTDANIQMPPGNQSAPQKNSESAYILFYQARDYA 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	223/416 (54%)
usp-46	NP_499162.2	UCH	26..403	CDD:278850	223/417 (53%)
		Peptidase_C19G	28..404	CDD:239128	223/416 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159002
Domainoid	1	1.000	432	1.000	Domainoid score	I295
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56957
Inparanoid	1	1.050	456	1.000	Inparanoid score	I888
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54027
OrthoDB	1	1.010	-	-		D378361at2759
OrthoFinder	1	1.000	-	-		FOG0001354
OrthoInspector	1	1.000	-	-		oto18965
orthoMCL	1	0.900	-	-		OOG6_101733
Panther	1	1.100	-	-	LDO	PTHR24006
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2327
SonicParanoid	1	1.000	-	-		X844
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940