Protein Alignment Usp12-46 and usp46

DIOPT Version :9

• Sequence 1: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001231910.1
• Gene: usp46 / 100148916
• ZFINID: ZDB-GENE-070705-213
• Length: 370
• Species: Danio rerio
• Alignment Length: 422
• Identity: 267/422 - (63%)
• Similarity: 307/422 - (72%)
• Gaps: 63/422 - (14%)

  Fly     1 MGANVSQLEREIGSDLFPPNEHYFGLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRPKET 65
            ||.|.|.||::||.:.||.|||||||||||||||.||||||||||:||||.||.||.:.|: ||.
Zfish    12 MGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKVQQKK-KEN 75

  Fly    66 LLSCLADLFYSIATQKKKVGSIAPKKFITRLRKEKEEFDNYMQQDAHEFLNFLINHINEIILAER 130
            ||:||||||:||||||||||.|.|||||:|||||.:.||||||||||||||:|:|.:.:|:..||
Zfish    76 LLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTVADILQEER 140

  Fly   131 NAGPSNGNPKATNQGGSTSAMASSIASKSSSTSNSNSNSNSTTNSNGNSSNSTGSLNANTSVLDA 195
            .....||..|  |.|       ::||:.:....|
Zfish   141 KQEKQNGRLK--NNG-------TAIATDTEPEQN------------------------------- 165

  Fly   196 SGSLTATTTPIISGNGTGTNGANSEPTWVHEIFQGILTSETRCLNCETVSSKDENFFDLQVDVDQ 260
                                  ..:||||||||||.||:|||||||||||||||:|.||.|||:|
Zfish   166 ----------------------KIDPTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQ 208

  Fly   261 NTSITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILALHLKRFKYMEQFNRHIK 325
            |||||||||.|||||||||:.|:.|:.|||.||||||||||||||||||||||||||||.:|:.|
Zfish   209 NTSITHCLRDFSNTETLCSEYKYYCEMCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTK 273

  Fly   326 VSHRVVFPLELRLFNTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKSHGLWLLFDDDMVDK 390
            :|:||||||||||||||.||||.||:|||.|||:||||||||||||:||||||.|||||||:|:|
Zfish   274 LSYRVVFPLELRLFNTSGDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEK 338

  Fly   391 IEASTIEDFYGLTSDIHKSSETGYILFYQSRD 422
            |:|..||:||||||||.|:||:|||||||||:
Zfish   339 IDAQAIEEFYGLTSDISKNSESGYILFYQSRE 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	248/393 (63%)
usp46	NP_001231910.1	UCH	34..366	CDD:278850	249/394 (63%)
		Peptidase_C19G	36..367	CDD:239128	248/393 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580200
Domainoid	1	1.000	486	1.000	Domainoid score	I379
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56957
Inparanoid	1	1.050	527	1.000	Inparanoid score	I1196
OMA	1	1.010	-	-		QHG54027
OrthoDB	1	1.010	-	-		D378361at2759
OrthoFinder	1	1.000	-	-		FOG0001354
OrthoInspector	1	1.000	-	-		otm24593
orthoMCL	1	0.900	-	-		OOG6_101733
Panther	1	1.100	-	-	O	PTHR24006
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2327
SonicParanoid	1	1.000	-	-		X844
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940