Protein Alignment Nepl15 and Nepl18

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 703
• Identity: 218/703 - (31%)
• Similarity: 356/703 - (50%)
• Gaps: 39/703 - (5%)

  Fly     1 MASQPLGL-LLGAILFSIC-AIDASVP--HPLAANYSIDILRLAKAAHIKAYMGDEKEQACNNFY 61
            |.|:.|.| ||.||:.::. ..||..|  ..|.::|:..|:..||.|.:|..|..| ...|::||
  Fly     2 MTSRVLWLCLLVAIVPAMAKPSDAGDPFADDLTSDYAKKIIVQAKVAEMKTMMKPE-VSPCDDFY 65

  Fly    62 NYACANWPRLHPAR-KSKTRTNYLEELQELYIRKSADMLKSATRGAENSADRQLKYFYGSCRLQT 125
            .:||.||.|.:||: .....|:..:.:.:.:.|:...:|::  ...::..:::::.||.||.|..
  Fly    66 THACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLRA--NDLQSELEKKMQRFYMSCNLVH 128

  Fly   126 NDTRSALNTLQNVTDFRGGWPEIRVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKM 190
            .|.......|:||....|..|.:..|.|...::.|.:.||.::.|.|..|.||||::.|.:...:
  Fly   129 RDDVHYKLALENVIREYGTLPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIRNTSV 193

  Fly   191 HRLKIGAPQFPMSRRHYLHPHFEGTREIYERSIENKLKLYFPEQSEHWRQEVASQVVQIEQQLAK 255
            :|:.|..|.|..     ::.......|....|::  |:.|| ..|....:..|.|:.::|:..:.
  Fly   194 NRVYISQPDFKT-----INTRLTNLMEEVRTSMD--LQQYF-GLSSSVAKHTAEQLTELERTFSS 250

  Fly   256 GLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIF-NDNLYMDLYETPEDYMSNLVDVIR 319
            |  .:.|.||.::....|.|:::..|..:::.|.:|.||. .:|:...||...|:|:...:..:|
  Fly   251 G--GSGAATLQESLSLYTVADLQEKYSDHLNFTEFLGLILGEENIPKSLYIYDEEYLDKALLTMR 313

  Fly   320 ETPKLQLANYTMWKALEALDIARVPASQRADIWCVQLAQQFFPHQLESLFHRNYNHMQMINELQS 384
            .||....|||.:||.||...:...|.....  ||.:..:::|....|...::.|.:..:.:|:..
  Fly   314 STPLATQANYVLWKLLEDFLVDAQPKDMVK--WCTESTKKYFGKLAEHAVYKRYRNPDVESEVHK 376

  Fly   385 TWSDIKRVFREDLQASERLLWLTLETRQKAITKLEALKLHFRTHDDNKLIRQMHGLILNMDR--F 447
            .|..||.:||:.| ..::|.|::..||..||.|||.:.|:..::|:.. ...::|.:. :||  :
  Fly   377 IWDQIKGIFRQRL-LGDKLDWISNATRTLAIEKLERMHLNINSYDEEN-FENVYGEVF-IDRLNY 438

  Fly   448 YPNLVSVLQWKTQRGLAKLMTEPVAEDEVHKL----PHYEIQKNRIQVPITFLQARFFWDPAYPN 508
            ..|:..:|..|..|.:|:: .:|....:..:|    |.|.||:|.|.:|:..||.|:||...||.
  Fly   439 VSNVQQLLIAKGIRFVARI-NQPADSVDATELLGFTPAYNIQENNITIPVALLQPRYFWGDQYPE 502

  Fly   509 GLKYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVEYKGKP 573
            .|||||||.|||.:||||||..||:|||.|....|||..|...:..|.:|||.||..: :|.|..
  Fly   503 ALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEY-QYGGSK 566

  Fly   574 VQDKDLLRRIVADNGALDIAYRAYQQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYCTD 638
            :.:.......:||:|.|.:||.||:.||...:|.  :.|||.:..|..:..|:|:||||||.|.|
  Fly   567 LPESKDQSENIADSGGLKLAYAAYELWLGQQSEE--VLQRETMEGLPFNSRQLFFLGYAQLLCDD 629

  Fly   639 ----YPETVERFD-ELPEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686
                :...|.:.| ..|.:.||...|||.|:|...:.||:...::..:||.:|
  Fly   630 VQFLFQPWVSQSDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	196/640 (31%)
Nepl18	NP_651643.1	M13	58..679	CDD:341056	195/641 (30%)