Protein Alignment Nepl15 and Nepl17

DIOPT Version :9

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 716
• Identity: 185/716 - (25%)
• Similarity: 328/716 - (45%)
• Gaps: 86/716 - (12%)

  Fly     8 LLLGAILFSICAIDASVPHPLAANYSIDILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLH 72
            |.:|::     ||...|...|.......|:|:||:|.:.::| |.....|::||.|||.|:..::
  Fly    15 LAVGSL-----AIQGGVFKELTTPLGQQIMRIAKSAEMCSFM-DTSVSPCDDFYGYACGNYATIN 73

  Fly    73 PARKSKTRTNYLEELQELYIRKSADMLKSATRGAENSADRQLKYFYGSC----RLQTNDTRSALN 133
            .|...|. ||..:.:...|:|:...:|.......:...:.::||||.||    .|:|......|:
  Fly    74 AATSQKD-TNIRQLMFANYLRRVRQVLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLS 137

  Fly   134 TLQNVTDFRGGWPEIRVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKMHRLKIG-- 196
            .|:..    ||.|.:...||....:|.::::|.|.|:.|....:|:.|:.|:...::.||::|
  Fly   138 VLREF----GGMPAVEGKSWDYVGFDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQR 198

  Fly   197 -----APQFPMSRRHYLHPHFEGTREIYERSIENKLKLYFPEQSEHWRQEVASQVVQIEQQLAKG 256
                 :.:|....:.|          ..:..:.|.|.|     ||...::.|.:::::|.:|::.
  Fly   199 LDLAESDEFASLWKKY----------ALKMRLRNLLGL-----SEELARKTAEEIIELELELSRS 248

  Fly   257 -----LPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFNDNLYMDLYETPEDYMSNLVD 316
                 :..:|.|....|    ..:.|..|||..::|||::.........:.::|:...|:..:..
  Fly   249 AFDHRMNRDPRLMRHLT----MLSNMSDAYGPILNVTRFVTSWLGSEYNLPVFESVPSYLFQVKK 309

  Fly   317 VIRETPKLQLANYTMWKALEALDIARVPASQRADIWCVQLAQQFFPHQLESLFHRNYNHMQ---- 377
            ::..||...:|||.:...|...:|......|:  :.|.:...:.||..::   |..|:.::
  Fly   310 ILLSTPNHVVANYMLSSLLTDFEITANEEQQK--VICHERITELFPDVVD---HMVYHSLEQQNP 369

  Fly   378 -MINELQSTWSDIKRVFREDLQASERLLWLTLETRQKAITKLEALKLHFRTHDDNKLIRQMHGLI 441
             :.||::|.|.::|..|||.| :|..:.||..:||::.:.||..:..............|...|:
  Fly   370 YIANEMRSLWVELKSSFREML-SSPDIEWLEKQTREELLEKLNGMSFEIAGGQAVNFEEQFGDLV 433

  Fly   442 LNMDRFYPNLVSVLQWKTQRGLAKLMTEPVAEDEVHKL---PHYEIQKNRIQVPITFLQARFFWD 503
            ::...:|.|:..:|:.|.:.....|:.|..:....|.:   |.||.:.|.:.:|::::|.|:.||
  Fly   434 VSSADYYGNIQRLLEVKARILRTDLLRESSSVYYYHGVTATPIYETETNLVVLPVSYMQHRYLWD 498

  Fly   504 PAYPNGLKYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYA--IF 566
            ..||..|||.|||..:|.:|.||||.:.|.||:.|..|:.|...::..:.....|..:|::  ::
  Fly   499 DIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFSGMLY 563

  Fly   567 VEYKGKPVQDKDLLRRI------VADNGALDIAYRAYQQWLKNAAETPVIYQRERLPLLDHDHNQ 625
            ...:         |||:      :|||..:.||..||.:||....    :.:.|.||.:.....|
  Fly   564 GNLR---------LRRLKSQAESIADNVGIRIAQSAYWKWLDQVE----MEETESLPHMTQSPEQ 615

  Fly   626 IFYLGYAQLYCTD-YPETVERF----DELPEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTL 685
            :|:|..||..|:| |||....|    ...|.:.||...:.||..||.|:.||...|:|...||.:
  Fly   616 LFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLM 680

  Fly   686 Y 686
            |
  Fly   681 Y 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	57..684	CDD:189000	170/663 (26%)
		PepO	57..677	CDD:226118	167/656 (25%)
Nepl17	NP_651641.1	PepO	49..672	CDD:226118	169/666 (25%)
		M13	55..678	CDD:189000	169/665 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454921
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0007609
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850