Protein Alignment Nepl15 and Nepl16

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Alignment Length: 768
• Identity: 151/768 - (19%)
• Similarity: 268/768 - (34%)
• Gaps: 240/768 - (31%)

  Fly     8 LLLGAILFSICAIDASVPHPLAANYSIDILRL----------------AKAAHIKAYMGDEKEQA 56
            |:...|||.|    ::.|.||..:..:|..|.                |.|:.|:|.:...|: .
  Fly   118 LVASPILFLI----STAPSPLPRDCYMDGDRCSPAVSAPPECSDPICEAVASSIQARLNWNKD-P 177

  Fly    57 CNNFYNYAC-ANWPRLHPARKSKTRTNYLE--------ELQELYIRKSADMLKSATRGAENSADR 112
            |..|..::| .|.|       :|..||.:|        :.|.||:.::..|         |.:..
  Fly   178 CTEFKKFSCWRNTP-------NKNITNLIEMGNSQKSVDSQMLYLFQNKIM---------NGSFG 226

  Fly   113 QLKYFYGSCRLQTNDTRSALNTLQNVTDFRGGWPEI------RVASWYQYEYDWLQVVANLKRKL 171
            .|...:.||..||.::    ..:..:.|..||:..:      .:|......||           |
  Fly   227 ILHNLFESCLQQTTNS----TVMHRIFDSLGGYLPVGSVGPSSIAPLIAKIYD-----------L 276

  Fly   172 G----VDIFIGL------------------EVILDYKEEKMHRLKIGAPQFPMSRRHYLHPHFEG 214
            |    ||::..|                  ..||:.|...|      :|:.|.||..      :|
  Fly   277 GPSPLVDLYHDLSYGRRPHILLIISGPSTSSTILERKIRWM------SPKAPPSRIR------QG 329

  Fly   215 TREIYERSIENKLKLYFPEQSEHWRQEVASQVVQIEQQLAKGLPHNPALTLAQTTRQRTAAEMKT 279
            ..::....|||.|. ||..    :.|.|:.:.                 |:.:..:.....:::.
  Fly   330 VPKLLADLIENFLP-YFVS----YAQRVSEKD-----------------TIFEFIKDLNKLQVEH 372

  Fly   280 AYGSYVDVTRYLQLIFNDNLYMDLYET-------PEDYMSNLVDVIRETPKLQLANYTMWK---- 333
            :...:.|.|    :::|.:...|||..       |:::...:  |:|.:..|:...|.:.|
  Fly   373 SRRGFWDST----VLYNVSSLQDLYPVLNWTLLIPQNWSGPI--VVRNSDYLKALEYFLTKYPTR 431

  Fly   334 -------ALEALDIARVPASQRADIWCVQLAQQFFPHQLESLFHRNYNHMQMINELQSTWSDIKR 391
                   .|.||.|  :|....:...|.:......|....||:...::.    .:|:.|....:.
  Fly   432 VAHNSLLLLSALQI--LPRDYPSPEVCTRSTMWALPELSSSLYIAQHSS----EDLKDTTKRAEI 490

  Fly   392 VFREDLQASERLLWLTLETRQKAITKLEALKLHFRT----HDDNKLIRQMHGLILNMDRFYPNLV 452
            :|: .|:|.   |......:..|:.||.|||:..:|    .:...|::.:..|.:..:.::.|::
  Fly   491 IFK-SLKAH---LKRAPSLKGAALVKLSALKIQSQTWEGFSNTTDLLKSLQPLNITSECWFQNIL 551

  Fly   453 SVLQWKTQRGLAKLMTEP------VAEDEVHKLP-----HYEIQKNRIQVPITFLQARFFWDPAY 506
            .:.:        |...||      ....:....|     .|:...:.|.||::.:...:| :...
  Fly   552 EIYK--------KNKLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPLSVILIPYF-NAVL 607

  Fly   507 PNGLKYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVEYKG 571
            |..|.||::||.:|:::|.   .:.:.:|                 .:..:|......||..|..
  Fly   608 PPYLHYASVGVSIAKEILR---SITKSFD-----------------EKAMRCVPHSVNIFSNYSR 652

  Fly   572 KPVQDKDLLRRIVADNGALDIAYRAYQQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYC 636
            ..         |:..:|.:.|:|.:.      .:.|..|....|||.|:....|||:|..||..|
  Fly   653 MD---------ILIHSGGMQISYHSM------LSLTGPIKGMARLPGLNLTPTQIFFLVSAQELC 702

  Fly   637 TDYPETVERFDELPEQLRVNTALSNSQQFAN------AYGCSREEKLNARFKC 683
            .:           ...|.::|   |:.:|.|      |.|.|..|.    |||
  Fly   703 AE-----------SNYLGIDT---NAPEFDNILGWLVAQGGSATEV----FKC 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	136/704 (19%)
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	136/706 (19%)