Protein Alignment Nepl15 and Nepl14

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Alignment Length: 718
• Identity: 180/718 - (25%)
• Similarity: 317/718 - (44%)
• Gaps: 106/718 - (14%)

  Fly    24 VPHPLAANY-SIDILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLHPARKSKTRTNYLEEL 87
            :|.|....| |...:|.:||..:.::: ::....|.:||.|||.||         |:.....::|
  Fly    30 LPPPFQRIYQSEQTVRRSKAQDMGSHV-NKSIDPCVDFYAYACGNW---------KSTLTPQQQL 84

  Fly    88 QELYIRKSADMLKSATRGAENSADRQLKYFYGSC-RLQTNDTRSALNTLQNVTDFRGGWPEIRVA 151
            |:...|:...:::.|.|..::...||.|..:.|| ..|.:.::...:.|....:..||:|.:..:
  Fly    85 QQQTDRELLLLVEEAVRREDSVIVRQAKELFKSCVSAQAHQSQQQQHFLSEFINQNGGFPAVPGS 149

  Fly   152 SW--YQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKMHRLKIGAPQFPMSRRHYLHPHFEG 214
            .|  :.::|:||.|:..|:.:.|:||.|||.|..:|.....:.|.:..|...:..........:.
  Fly   150 QWAVHHHDYNWLSVLGGLRLRYGMDILIGLRVGYNYGNVNENSLYLSEPSTLIPTELCTRNRSDI 214

  Fly   215 TREIY---ERSIENKLKLYFP---EQSEHWRQEVASQVVQIEQQLAKGL--------PHNPALTL 265
            ...||   |..:.::||.:..   ::|    ..:|:.::..|.:|..|:        .....|.|
  Fly   215 RDSIYEPLEHRVASELKSWLALGHDES----ARLAADILSFEHELCGGMKGGSFESWDAEEQLYL 275

  Fly   266 AQTTRQRTAAEMKTAYGSYVDVTRYLQLIFNDNLYMDLYETPEDYMSNLVDVIRETPKLQLANYT 330
            |..|| :|..|...:.  .:|:..|::..|..::|..:|....:|...|...:.......:|||.
  Fly   276 ANYTR-KTLREFSNSI--ELDLDSYVRASFGQDIYKPVYMAAPEYFRQLKRTVSAHNISLVANYI 337

  Fly   331 MWKALEALDIARVPASQRADI---WCVQLAQQFFPHQLESLFHRNYNHMQMINELQSTWSDIKRV 392
            |::|:.||:.   |...|..:   .|::..::..|..|..|:.|.:.......:|.:.:..:|..
  Fly   338 MYRAVSALNF---PLDDRPQLRKRECLERTKELLPTALGELYARQFGTEDGRIDLDNLYDTLKTA 399

  Fly   393 FREDLQASERLLWLTLETRQKAITKLEALKLHFRTHDDNKLIRQMHGLILNMDRFYPN---LVSV 454
            .|:.|.|.    ||...|::....||..|||...|::...:::    |.|....::.|   |:.|
  Fly   400 LRQSLGAE----WLVEGTQRVGQEKLRNLKLQMPTYERPVILK----LQLERGNYWQNLRQLLGV 456

  Fly   455 LQWKTQRGLAKLMTE--PVAEDEVHKLPHYEIQ------KNRIQVPITFLQARFFWDPAYPNGLK 511
            :|  :||. .:|..|  |...|.|..   ||.:      :.|:.:.:..||...: ||.|.:.::
  Fly   457 VQ--SQRN-NRLFEEFLPAPTDPVEA---YEARVRLRPVQRRLDMGLALLQPPAY-DPRYGHAIR 514

  Fly   512 YATLGVLLARQMLHGFD----GVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVEYKGK 572
            ||||||.||:|::..||    .||.      .:.:.||..:...|..|:.||..|    |:...:
  Fly   515 YATLGVQLAQQLVMAFDDPHWSVGL------LERDNWDGQTAWQYHIRSNCFARQ----VDNYLR 569

  Fly   573 PVQDKDLLRRIVADNGALDIAYRAYQQWL----KNAAETPVIYQRERLPLLDHDHNQIFYLGYAQ 633
            |  :.....:::.|:.|:::|:|||..||    .|...|.:  .:|.||.|::.:..:|:|.|||
  Fly   570 P--NVSATTQLITDSAAINVAFRAYLTWLGFQEPNNDFTKL--TKETLPDLNYSNTALFFLAYAQ 630

  Fly   634 LYCTDYPETVERFDE--LPE-------------QLRVNTALSNSQQFANAYGCSREEKLNARFKC 683
            .:|:  .|.....||  .||             :|.||..|.||.:||:.:.|.....:|...||
  Fly   631 EHCS--LEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNPASKC 693

  Fly   684 TLY 686
            .:|
  Fly   694 IIY 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	171/681 (25%)
Nepl14	NP_651097.1	M13	60..693	CDD:341056	170/682 (25%)