Protein Alignment Nepl15 and Nep4

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Alignment Length: 818
• Identity: 201/818 - (24%)
• Similarity: 334/818 - (40%)
• Gaps: 203/818 - (24%)

  Fly    37 LRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLHPARKSKTRTNYLEELQE---LYIR----- 93
            :|:.:|..:|.|| |.|...|.:||.|||.||.||||..|.|...:..|.|:|   |.:|
  Fly   258 IRMTQAKTMKRYM-DNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEK 321

  Fly    94 -----KSADMLKSATRG----------AENSAD-----------------RQL---------KYF 117
                 .:|::.||..|.          .|..||                 |||         :|.
  Fly   322 NTPVHSAAELRKSPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYT 386

  Fly   118 YGSCRLQTNDT----------------------------------------------------RS 130
            .|:.|.:..:|                                                    ||
  Fly   387 NGTKRKRLIETPRERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRS 451

  Fly   131 ALNT----------LQNVTDFRGGWPEIRVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDY 185
            .:|:          |..:....||||.:. :.|.:..::| ||:|...|:...||.|...|..|.
  Fly   452 CVNSAVLAKRGLEPLHTLIRELGGWPVLE-SQWSESNFNW-QVLAATLRRYNNDILIVQWVGADI 514

  Fly   186 KEEKMHRLK-----IGAPQFPMSRRHYLHPHFEGTREIYERSIENKLKLYFPEQSEHWRQEVASQ 245
            |..:.:.::     :|.|    :|.::|.|......:.|:|.:...:......:::  .|.|||:
  Fly   515 KNSEENIVQFDQTGLGLP----TREYFLQPSNAKYLQAYQRYMAEVMHKMGASKAD--AQRVASE 573

  Fly   246 VVQIEQQLAKGL--PHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFNDNLYMDLYETPE 308
            :|..|.||| |:  |....|.:.:..::.|..::: |....:....|||.:.:    .::..|.|
  Fly   574 LVAFETQLA-GITAPAEQRLNVTKLYKRMTLDQLQ-AVVPEIKWRAYLQSLQD----REVLGTEE 632

  Fly   309 ------DYMSNLVDVIRETPKLQLANYTMWKAL-------------------EALDIARVPASQR 348
                  :|||.||.::.||....::||.||:.:                   .|| ..|..:.||
  Fly   633 VVIYAVEYMSKLVTLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHAL-FGREESPQR 696

  Fly   349 ADIW--CVQLAQQFFPHQLESLF-HRNYNHMQMINELQSTWSDIKRVFREDLQASERLLWLTLET 410
               |  |:..........:.|:| .|.:::....:.|:.| .|:::.||:.|:.::   ||...|
  Fly   697 ---WKVCIAQVNTNMGMAVGSMFVSRYFDNNSKRDTLRMT-HDLQQAFRDILKTTD---WLDDTT 754

  Fly   411 RQKAITKLEALKLHFRTHD----DNKLIRQMHGLILNMDRFYPNLVSVLQWKTQRGLAKLMTEPV 471
            :|.|..|:.|:.|.....|    .::|..:..|:.:..::::.|.::||....:...|||
  Fly   755 KQLAEEKVNAMSLKIGYPDFILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKL----- 814

  Fly   472 AEDEVHKL----------PHYEIQKNRIQVPITFLQARFFWDPAYPNGLKYATLGVLLARQMLHG 526
             .:.|:|.          .:|...||:|..|...||..|: ...:|..|.:..:||::..::.||
  Fly   815 -HERVNKTNWQTAPAIVNAYYSRNKNQIMFPAGILQPPFY-HRHFPKSLNFGGIGVVIGHELTHG 877

  Fly   527 FDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIF-VEYKGKPVQDKDLLRRIVADNGAL 590
            ||..||.:|..|..:.||..:|...:..|.:|...||:.: ||..|..:..:......:||||.|
  Fly   878 FDDKGRLFDRNGNIHKWWTDSSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGL 942

  Fly   591 DIAYRAYQQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYC-TDYPETVERFDEL----- 649
            ..|:.|||:|||   |.|.....|.||.|:....|:|:|.:.|::| ...||.:.  ::|
  Fly   943 RQAFHAYQRWLK---EHPSEVSDEILPGLNMTGPQLFFLNFGQVWCGAMRPEAIR--NKLNTAIH 1002

  Fly   650 -PEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686
             |.:.||...||||..||..:.|.....:|.:.||:::
  Fly  1003 SPGRFRVIGTLSNSVDFAREFNCPLGSPMNPQKKCSVW 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	193/795 (24%)
Nep4	NP_650904.3	M13	274..1038	CDD:341056	193/797 (24%)