Protein Alignment Nepl15 and Nepl12

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 756
• Identity: 171/756 - (22%)
• Similarity: 289/756 - (38%)
• Gaps: 228/756 - (30%)

  Fly    29 AANYSIDILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLHPARKSK-TRTNY------LEE 86
            ||.|.:.    ..|..:|:|| ::..:.|.|||.|||.|:..:.|.|.|. :|:|.      |.:
  Fly    48 AAEYQLQ----EYAEFMKSYM-NQSVEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDVTYTLID 107

  Fly    87 LQELYIRKSADMLKSATRGAENSADRQLKYFYGSCRLQTN------DTRSALNTLQNVTDFRGGW 145
            :.|..:.: .|:.::....:|.:..::   ||.:| |..|      ...:.|:.::::    ||:
  Fly   108 ITEQLLGR-MDLAEALNVSSELAVAQR---FYNAC-LGANLHPFNAADPAYLSLIRSI----GGF 163

  Fly   146 PEIRVASWYQYEYDWLQVVANLKR------------------------KLGVDIFIGLEVILD-- 184
            |.:...:|....::|:.:.|:|..                        :||.|..|..|..:.
  Fly   164 PAVDGDAWKASNFNWINMSAHLANYGANGLIRETLQLRYPFEPYTKLPELGFDHIIVHEENISRN 228

  Fly   185 ------YKEEKMHRL--KIGAPQFPMSRRHYLHPHFEGTREIYERSIE----------NKLKLYF 231
                  ..||:||..  ..|.|:      ..:.....|....:..::|          .::|..|
  Fly   229 TTRAFRLNEERMHGYLRAFGLPE------DRIREAIAGVFAFWRDALEIPPQCEVFDPYRIKRVF 287

  Fly   232 PEQSEHWRQEVASQVVQIEQQLAKGLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFN 296
            | |||::                    :|.:.:...:|.:                      :|.
  Fly   288 P-QSEYY--------------------YNISWSGLHSTNK----------------------LFC 309

  Fly   297 DNLYMDLYETPEDYMSNLVDVIRETPKLQLANYTMWKALEALD-IARVPASQRADIWC-VQLAQQ 359
            |..|::|            |.:....:..:|||...|.|...| ..:.|..||.  :| |.|.|
  Fly   310 DFYYVEL------------DKVCARHRKAVANYLAMKLLYRFDPKLKAPRYQRN--YCSVTLYQ- 359

  Fly   360 FFPHQLESLFHRNY--NHMQMINELQSTWSDIKRVFREDL-QASERLLWLTLETRQKAITKLEAL 421
                .:..||::.|  |:......|:  .|::.|..|:.| :|.|...||..|:|.:|:.|...:
  Fly   360 ----SMRFLFNKLYMANNFSEAKRLE--MSEMVRELRKSLRKALEDADWLDAESRARALLKESRI 418

  Fly   422 KLHFRTHDD----NKLIRQMHGLILNMDRFYPNLVSVLQWKTQRGLAKLMTEPVAEDEVHKLPHY 482
            :....:..|    :::||:::.|.:..||:                        ||..:: |.|.
  Fly   419 QPRIGSFQDDALSDRIIREINSLKVIEDRY------------------------AETNIN-LQHL 458

  Fly   483 EIQKNRI--------------QVPITFLQ---------------ARFFWDPAY----PNGLKYAT 514
            .:|.||.              |..:|.||               |.....|.|    |..||:.|
  Fly   459 VVQINRFSSRHFQELTNDTKPQKILTGLQVGAGYYTPDNSINVMAGVVEPPIYQRHLPISLKFGT 523

  Fly   515 LGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIF-VEYKGKPVQDKD 578
            ||.::..:::||||.....:|..|:..:.....|:.:...|.:|:.:.|..: |....:.|..|.
  Fly   524 LGFIVGHELIHGFDTTSSYFDGNGHMESLLSEISQQALEDRAECYMDYYGKYQVPEISRRVNGKT 588

  Fly   579 LLRRIVADNGALDIAYRAY----QQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYCTDY 639
            .|...:|||..|..|..||    ||.|::..:..:   .:.:|.||....|:|:||:|||:|:.|
  Fly   589 TLDENIADNSGLRQALTAYRSHRQQLLEHPGQERI---SDAMPGLDLTPEQLFFLGFAQLFCSHY 650

  Fly   640 PE--------TVERFDELPEQLRVNTALSNSQQFANAYGCS 672
            .|        .|..||    |.||...||||:.|.:||.||
  Fly   651 EEEHYWKGLSDVHTFD----QFRVLGVLSNSEDFFHAYNCS 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	164/729 (22%)
Nepl12	NP_649924.1	M13	68..700	CDD:341056	164/731 (22%)