Protein Alignment Nepl15 and Ece2

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_038944493.2
• Gene: Ece2 / 408243
• RGDID: 1303039
• Length: 789
• Species: Rattus norvegicus
• Alignment Length: 643
• Identity: 162/643 - (25%)
• Similarity: 274/643 - (42%)
• Gaps: 106/643 - (16%)

  Fly    51 DEKEQACNNFYNYACANWPRLHPARKSKTRTNYLEEL--QELYIRKSADMLKSATRGAENSADRQ 113
            |.....|.:||.::|..|.|.:|....::|.|....|  |...|.|  .:|:::|..:.:.|:|:
  Rat   189 DRGVSPCQDFYQFSCGGWIRRNPLPSGRSRWNTFNSLWDQNQAILK--HLLENSTFNSSSEAERK 251

  Fly   114 LKYFYGSCRLQTNDTRSALNTLQNVTDFRGGWPEIRVASWYQYEY-DWLQVVANLKRKLGVDIFI 177
            .:.||.||.......:.....||::.|..|||.  ....|.:..: :.|:.||...|...   |.
  Rat   252 TRSFYLSCLHLERIEKLGAKPLQDLIDKIGGWN--ITGPWDEDNFMEVLKAVAGTYRAAP---FF 311

  Fly   178 GLEVILDYKEEKMHRLKIG-APQFPMSRRHYLHPHFEGTREIYERSIENKLKLYFPE-------Q 234
            .:.|..|.|....:.:::. :..|..||.:||:      |...|:.:...|. |..|       |
  Rat   312 TVYVGADSKSSNSNIIQVDQSGLFLPSRDYYLN------RTANEKVLAAYLD-YMVELGMLLGGQ 369

  Fly   235 SEHWRQEVASQVVQIEQQLAKGLPHNPALTLAQTTR--------QRTAAEMKTAYGSYVDVTRYL 291
            ....|.:: .||:::|.|||       .:|:.|..|        :.:.:|::|...| :|...:|
  Rat   370 PTSTRAQM-QQVLELEIQLA-------TITVPQDQRRDEEKIYHKMSISELQTLAPS-MDWLEFL 425

  Fly   292 QLIFN-----DNLYMDLYETPEDYMSNLVDVIRETPKLQLANYTMW------------------- 332
            ..:.:     |:..:.:|.|  :|:..:.::|..|....|.||.:|
  Rat   426 SFLLSPLELGDSEPVVVYGT--EYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFETAQE 488

  Fly   333 KALEALDIARVPASQRADIW--CVQLAQQFFPHQLESLFHRNYNHMQMINELQSTWSDIKRVFRE 395
            |.||.|...:...:.|   |  |:..........|.|||.:.....|.....:...|:|:..|.|
  Rat   489 KLLETLYGTKKSCTPR---WQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEE 550

  Fly   396 DLQASERLLWLTLETRQKAITKLEALK---------LHFRTHDDNKLIRQMHGLILNMDRFYPNL 451
            .|   |.|:|:..:||..|..|.:|:.         |..|..||     ...|..::.|.|:.|:
  Rat   551 TL---ENLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPRELDD-----VYDGYEVSEDSFFQNM 607

  Fly   452 VSVLQWKTQRGLAKLMTEPVAEDEVHKLP-----HYEIQKNRIQVPITFLQARFFWDPAYPNGLK 511
            :::..: :.:.:|..:.:|.:.|:....|     :|...||.|..|...|||.|: ...:|..|.
  Rat   608 LNLYNF-SAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFY-AHNHPKALN 670

  Fly   512 YATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVEYKGKPVQD 576
            :..:||::..::.|.||..||.||..|....||.:.|.:::...|.|.:|||..: :..|:.:..
  Rat   671 FGGIGVVMGHELTHAFDDQGREYDQEGNLRPWWQNESLTAFQNHTACMEEQYNQY-QVNGERLNG 734

  Fly   577 KDLLRRIVADNGALDIAYRAYQQWL-KNAAETPVIYQRERLPLLDHDHNQIFYLGYAQ 633
            ...|...:||||.|..||.||:.|| |:..|.|       ||.:...::|:|::|:||
  Rat   735 LQTLGENIADNGGLKAAYNAYKAWLRKHGEEQP-------LPAVGLTNHQLFFVGFAQ 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	161/638 (25%)
Ece2	XP_038944493.2	None