Protein Alignment Nepl15 and Nep2

DIOPT Version :9

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Alignment Length: 709
• Identity: 155/709 - (21%)
• Similarity: 282/709 - (39%)
• Gaps: 116/709 - (16%)

  Fly    55 QACNNFYNYACANWPRLHPARKSKTRTNYLEELQELYIRKSADMLKSATRGAENSADRQLKYFYG 119
            :.|:|||.:||..:.........|...:....:.:....:..|::.:.....|....|.....|.
  Fly   105 EPCDNFYEFACGTYLEEENIPDDKVSISTFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYK 169

  Fly   120 SCRLQTNDTRSALNTLQNVTDFRGGWPEIRVASWYQYE-YDWLQVVANLKRK-LGVDIFIGLEVI 182
            :|..:|.........:..|.:..||||.|:..||...: :.|.:.|...:.. ..:|..|...:.
  Fly   170 ACMNKTLIETLGPEPITRVAERLGGWPLIKGDSWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIG 234

  Fly   183 LDYKEEKMHRLKIGAPQFPMSRRHYLHPHFEGT--REIYERSIENKLKLYFPEQSEHWRQEVASQ 245
            :|.:......:.:......:| |.||...|..|  ...|:..::  :.:.|....:..:.|:...
  Fly   235 VDLQNSTKRLIDLDQSSLALS-REYLVKGFNETLVTAYYKYMVD--IAVLFGANRDLAKTELLLS 296

  Fly   246 VVQIEQQLAK-GLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFNDNLYMDLYETPED 309
             ::.|..||. ..|:......::....||.|:::.|| .||....|:..:..:.|     ...||
  Fly   297 -LEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAY-PYVQWVDYMNALLPEGL-----NVAED 354

  Fly   310 YMSNLV---------DVIRETPKLQLANYTMWKALEALDI----------------ARVPASQRA 349
            .|.||.         .::.:|||..:|||..|: :....:                |.....::.
  Fly   355 EMINLSVPSFFEDLGKLLAKTPKRVIANYMFWR-IHGFSVGFLSEEFRKRQLQYATALSGRQEQE 418

  Fly   350 DIW--CVQLA----QQFFPHQLESL------------FHRN--YNHMQMINELQSTWSDIKRVFR 394
            ..|  ||.:|    .:......:||            ||::  .|.::|:||:::.::||
  Fly   419 ARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHFHKDSKANALEMVNEIRNVFNDI----- 478

  Fly   395 EDLQASERLLWLTLETRQKAITKLEALKLHF----RTHDDNKLIRQMHGLILNMDRFYPNLVSVL 455
                 .:.:.|:..:|:::|..||.::..|.    ...|:.||......|.::.|:::.:.:.:.
  Fly   479 -----LDEVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAYYAKLDIDPDKYFESFLGMN 538

  Fly   456 QWKTQRGLAKLMTEPVAEDEV-HKLP-----HYEIQKNRIQVPITFLQARFFWDPAYPNGLKYAT 514
            .:.|.....||.......|.| |..|     .|...:|.||.|...||..|| :...|..:.:..
  Fly   539 IFGTDYSFNKLRLPVNKTDWVRHARPAIVNAFYSSLENSIQFPAGILQGHFF-NAQRPKYMNFGA 602

  Fly   515 LGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVE------YKGKP 573
            :|.::..::.||||..||::|..|...:||...::.:|..:.:|..|||..:.|      ..|..
  Fly   603 IGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAKAKCIIEQYGNYTERATGLNLNGIN 667

  Fly   574 VQDKDLLRRIVADNGALDIAYRAYQQWL-KNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYCT 637
            .|.::     :||||.:..:|.||::|. |:..|.       :||.||:...|:|::...|.:|.
  Fly   668 TQGEN-----IADNGGVKESYIAYRRWAEKHGPEA-------KLPGLDYTPEQMFWVAAGQTWCA 720

  Fly   638 DYPETVERFDEL----------PEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686
            .|     |.:.|          |.:.||..:|||.:.||..:.|.....:|...||.::
  Fly   721 KY-----RKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKCEVW 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	57..684	CDD:189000	154/703 (22%)
		PepO	57..677	CDD:226118	152/696 (22%)
Nep2	NP_001246914.1	M13	104..772	CDD:189000	154/705 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920