Protein Alignment Nepl15 and Nepl10

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 710
• Identity: 149/710 - (20%)
• Similarity: 274/710 - (38%)
• Gaps: 150/710 - (21%)

  Fly    10 LGAILFSICAIDASVPHPLAANYSIDILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLHPA 74
            :|.:|. :|:...::..|:.|...|::   |.:..|...: :.....|.||:|:||..:     :
  Fly     1 MGCLLL-LCSCLVALFIPIQAIVDINV---ATSNDIHNNL-NRTTSPCTNFWNFACGRF-----S 55

  Fly    75 RKSKTRTNYLEELQELYIRKSADMLKSATRGAENSADR---QLKYFYGSCRLQTNDTRSALNTLQ 136
            ..||...|: |.:::.:.....:.::|.....:..|.|   |::.:|.:|:   .|||......:
  Fly    56 SASKYVDNF-ERVEDQFATAMVEFMESHLGENDTLAPRLIKQMRQYYKACK---EDTRKLHGNPR 116

  Fly   137 NVTDFRGGWPEIRVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKMHRLKIGAPQFP 201
                     ||..|..|..:...:|....|       .:||...|.:...:.....:::..|. |
  Fly   117 ---------PEELVNQWILHPKKFLVYGLN-------GVFIDERVDVAANDSMRWVIQLRMPD-P 164

  Fly   202 MSRRHYLHPHFEGTREIYERSIENKLKLYFPEQSEHWRQEVASQVVQIEQQLAKGLPHNPALTLA 266
            ..|             ..:|.:...::||    .|.|......::|:...||
  Fly   165 ADR-------------YSDRRVLQLMRLY----EEAWYSMGVVKLVEKMHQL------------- 199

  Fly   267 QTTRQRTAAEMKTAY-GSYVDVTR--------YLQLI---FNDNLYMDLYETPE-DYMSNLVDVI 318
               :.:..||....| .|:.::.:        :::|:   ..:.||...:|..: :|:......:
  Fly   200 ---QDKYRAEYPVVYTWSFSELRQEIPIPHSFFIELLGVNHTEELYHLTFEVSDVEYLRECFRCL 261

  Fly   319 RE---TPK---LQLANYTMWKALEALDIARVPASQRADIWCVQLAQQFFPHQLESLFHR--NYNH 375
            |:   .||   ::...|.:.:..|..:  |.|.|      |:...:.:.|..:..::.|  ..|.
  Fly   262 RDFASEPKDTYIRARQYVLVEESEPRE--RNPRS------CIHHMRAYLPLGMNYIYDRFIYQNR 318

  Fly   376 MQMINELQSTWSDIKRVFREDLQASERLLWLTLETRQKAI--TKLEALKLHFRTHDDNK---LIR 435
            .:..:::....|.:|..|.:.|.|:.    |.|...|.|.  .|||.:::......:.|   ...
  Fly   319 EEDTSKVLEILSTLKAAFGQYLDANR----LQLTPNQLAYVRAKLEGIQIKIGNLPEEKSPEFYN 379

  Fly   436 QMHGLI-LNMDRFYPNLVSVLQWKTQRGLAKLMTEP--------VAEDEVHKL---PHYEIQKNR 488
            ..:|.. .:...|..||:.....:|:...|.|:...        ...|.|.|.   |.||.::|.
  Fly   380 NHYGSANFSATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKARTSPFYENERNT 444

  Fly   489 IQVPITFLQARFFWDPAYPNGLKYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESS-Y 552
            |.||:.|||...| |.......:::.||.:|..:|.|.|:..|..:||.|.::.......||. :
  Fly   445 ITVPMEFLQWPLF-DHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGNESPVGLEIRESKPF 508

  Fly   553 SRRTQCFQEQYAIFVEYKGKPVQDKDLLRRIVADNGALDIAYRAYQQWLKNAAE---TPVIYQRE 614
            ....:|.:||  .||..|.:           :||...|.:||.|:.....::.:   .|..:::|
  Fly   509 RDAIKCAEEQ--PFVSLKER-----------LADLNGLQLAYDAFFGLAHDSRQFEYRPYAFEQE 560

  Fly   615 -RLPLLDHDHNQIFYLGYAQLYCTDYPETV--ERFDELPEQLRVNTALSNSQQFANAYGC 671
             ..|       |:|:|.|||.:|...|..:  :|.||     |||.::.|.:|||..:.|
  Fly   561 FTAP-------QLFHLSYAQFFCGSLPPVIAHDRDDE-----RVNVSVGNLRQFAYDFNC 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	141/664 (21%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	140/663 (21%)