Protein Alignment Nepl15 and Nepl5

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 719
• Identity: 172/719 - (23%)
• Similarity: 289/719 - (40%)
• Gaps: 145/719 - (20%)

  Fly    42 AAHIKAYMGDEKEQACNNFYNYACANWPRLHPARKSKTRTNYLEELQELYIRKSADMLKSATRG- 105
            |..:::|| |.|.:.|.|||.|||.||......:.|....::..:.|    |....||.:.|.|
  Fly    37 AEQLQSYM-DTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQ----RYQGQMLPTDTLGL 96

  Fly   106 ----------------------AENSADRQLKYFYGSC-RLQTNDTRSALNTL--QNVTDFRGGW 145
                                  :::|...|::.:|.|| ||:..:.:..|..|  .|.|.    |
  Fly    97 IDHSVNRKLELLLRRRNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLLPPSNSTQ----W 157

  Fly   146 PEIRVASWYQYEYDWLQVVANLKRKLGVD-IFIGLEVILDYKEEKMHRLKIGAPQFPMSRRHYLH 209
            |.:. ..|....:||:..:..| |..|:: :.:..||:..:.:.:.:.:.:..|.     |....
  Fly   158 PSVG-RGWRPERFDWITTLGRL-RLHGLNGVLLREEVLPRWDDSRNYSIYVNKPS-----RQETQ 215

  Fly   210 PHFEGTREIYERSIENKLKLYFPEQSEHWRQEVASQVVQIEQQLAKGLPHNPALTLAQTTRQRTA 274
            |..||.      .||..|.:   .|::.....:|.||...|::|.:         |.:.......
  Fly   216 PMGEGA------MIELLLDI---GQTKRTANALARQVDDFERKLHR---------LQELEDDEGP 262

  Fly   275 AEMKTAY-GSYVDVTRYLQLIFNDNL--YMDLYET------PEDYMSNLVDVIRETPKLQLANYT 330
            .||:..| .||:...|:|..:....:  .:||..|      |  |:..|.|::.......:.:|.
  Fly   263 REMQLGYLDSYLPQLRWLSFMRQVRIDSELDLRSTLIIENIP--YLRALSDLMESESPDTVCSYI 325

  Fly   331 MWKALEAL------DIAR---VPASQR----ADIWCVQLAQQFFPHQLE----SLFHR---NYNH 375
            |.|.|..|      ||:|   |.|.:|    |..|.|  .|||...:.|    |||.|   .:..
  Fly   326 MLKWLAFLKQQGPADISRGECVAALRRAMPLASSWLV--GQQFSDPESESYVSSLFQRLKVRFGQ 388

  Fly   376 MQMINELQSTWSDIKRVFREDLQASERLLWLTLETRQKAITKLEALKLHFRTHD--DNKLIRQMH 438
            :...|.::.: ..:..:.::.|:| .||.....:|.:....:...:::....|.  .|:|:....
  Fly   389 ILAENRMRLS-PPLVHILQQKLRA-VRLQMGFFQTEEIEDVEQYHVRIDLSGHSFYGNQLVLLRQ 451

  Fly   439 GLILNMDRFYPNLVSVLQWKTQRGLAKLMTEPVAEDEVHKLPHYEIQKNRIQVPITFLQARFFWD 503
            .:..|.|..|.|:.:... .|...|:.|.....|.   :..|.|...:|.:.||...||.
  Fly   452 RVEANHDLLYINVTNFAN-STGSNLSYLSESWEAS---NSSPLYVRPRNLVLVPHGLLQL----- 507

  Fly   504 PAYPNGL----KYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRR----TQCFQ 560
            |.:...:    ::|.:|.:||.::.||||.:|..|||.|   |......|...||:    .||.|
  Fly   508 PIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMG---NIMGPVEEIGASRQFRQGLQCLQ 569

  Fly   561 EQYAIFVEYKGKPVQDKDLLRRIVADNGALDIAYRAYQQWLKNAAETPVIYQRE-RLPLL-DHDH 623
            :|.|.    ..|.:.:|      :||..||.:||..:         ..|..:|| |.||| ....
  Fly   570 QQMAT----GSKWIDEK------LADFVALRLAYETF---------FGVRDKREPRDPLLPQFSQ 615

  Fly   624 NQIFYLGYAQLYCTDYP------ETVERFDELPEQLRVNTALSNSQQFANAYGCSREEKLNARFK 682
            .|:|::.:||.:|...|      ::........::|||...|:|.::|:..:||.::.|:.|..:
  Fly   616 RQLFFITFAQFFCGRTPVLSPRSQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQASQR 680

  Fly   683 CTLY 686
            |.::
  Fly   681 CRIW 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	166/701 (24%)
Nepl5	NP_609022.1	M13	48..682	CDD:341056	166/703 (24%)