Protein Alignment Nepl15 and Nep3

DIOPT Version :9

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001245775.1
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 695
• Identity: 171/695 - (24%)
• Similarity: 311/695 - (44%)
• Gaps: 99/695 - (14%)

  Fly    57 CNNFYNYACANWPRLHPARKSKT---RTNYLEELQELYIRKSADMLKSATRGAENSADRQLKYFY 118
            |::||.|:|..|.:.:|..:.|:   ....||::.:|.||   ::|:...:..::.|:|:.|.:|
  Fly   126 CDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIR---NVLEKPAKSFKSDAERKAKVYY 187

  Fly   119 GSCRLQTNDTRSALNTLQNVTDFR---GGWPEIR----VASWYQYEYDWLQVVANLKRKLGVDIF 176
            .|| |..::....|.. :.:.|..   |||...:    ||:|....  .|:::.|   |...:..
  Fly   188 ESC-LDADEHMEKLGA-KPMNDLLLQIGGWNVTKSGYNVANWTMGH--TLKILHN---KYNFNCL 245

  Fly   177 IGLEVILDYKEEKMHRLKIGAPQFPMSRRHYLHPHFEGTREIYERSIENKLK---LYFPEQSEHW 238
            .|..:..|.|....|.::|......:....|.:...:..|::....||...|   |....:|:..
  Fly   246 FGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDAR 310

  Fly   239 RQEVASQVVQIEQQLAKGLPHNPALTLAQTTRQRTAA-------EMKTAYGSYVDVTRY----LQ 292
            .|.:.  |:..|::||.       :|:....|:...|       ...:....:::.|.:    :|
  Fly   311 AQMIG--VINFEKKLAN-------ITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQ 366

  Fly   293 LI---FNDNLYMDLYETPEDYMSNLVDVI-----RETPKLQLANYTMWKALEALDI--------- 340
            ::   ..|:..:.:|  ..|::.||.|:|     .|..|:.|.||.:|:|:..|..
  Fly   367 MVGRRVTDDEVVVVY--APDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDA 429

  Fly   341 ------ARVPASQRADIW--CVQLAQQFFPHQLESLFHRNYNHMQMINELQSTWSDIKRVFREDL 397
                  |.:.:....:||  ||..........:.::|.|...|.:.....:...::|:..|:.:|
  Fly   430 YKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNL 494

  Fly   398 QASERLLWLTLETRQKAITKLEALK--LHFRTH--DDNKLIRQMHGLILNMDRFYPNLVSVLQWK 458
            |   .|.|:..:||:|||.|...:.  :.|..:  |..:|.::...|.:..:.::.|.:.|..:.
  Fly   495 Q---NLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYN 556

  Fly   459 TQRGLAKLMTEPVAEDEVHKLP-----HYEIQKNRIQVPITFLQARFFWDPAYPNGLKYATLGVL 518
            .:..| |.:.:||.:......|     :|...||:|..|...||..|| |...|..|.:..:||:
  Fly   557 LKSNL-KRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFF-DINNPKSLNFGAMGVV 619

  Fly   519 LARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVEYKGKPVQDKDLLRRI 583
            :..::.|.||..||.||.:|..|.|||..|...::.:::|...||:.: :..|:.:..|..|...
  Fly   620 MGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGY-KMNGRTLNGKQTLGEN 683

  Fly   584 VADNGALDIAYRAYQQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYC---TDYPET--- 642
            :||||.|..||.|||: .|:..:..::    :||.|:..|:|:|::.:||::|   ||  ||
  Fly   684 IADNGGLKAAYHAYQR-TKSDRDVDIL----KLPGLNLTHSQLFFVSFAQVWCSSTTD--ETNLL 741

  Fly   643 -VERFDELPEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686
             :|:....|.|.||...|||.::||..:.|...:::|...||.::
  Fly   742 QMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	57..684	CDD:189000	170/691 (25%)
		PepO	57..677	CDD:226118	168/684 (25%)
Nep3	NP_001245775.1	M13	123..784	CDD:189000	170/691 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850