Protein Alignment Nepl15 and Kel

DIOPT Version :9

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_115929.3
• Gene: Kel / 23925
• MGIID: 1346053
• Length: 713
• Species: Mus musculus
• Alignment Length: 769
• Identity: 160/769 - (20%)
• Similarity: 269/769 - (34%)
• Gaps: 181/769 - (23%)

  Fly     7 GLLLGA-----ILFSICAIDASVPHPLAANYSIDILRLAKAAHIKAYMGDEKEQACNNFYNYACA 66
            |||||:     .:|..|.     |.|......:::|     .|..| .|:.....|.:|:::||
Mouse    37 GLLLGSSMLWFYIFRNCG-----PCPCETPVCMELL-----DHYLA-SGNRSVAPCTDFFSFAC- 89

  Fly    67 NWPRLHPARKSKTRTNYLEELQELYIRKSADMLKSATRGAENSADRQLKYFYGSCRLQTNDTRSA 131
                    .|:...::..:.|.|....:...:|::.......|.:.:...||.||........|.
Mouse    90 --------EKANGTSDSFQALTEENKSRLWRLLEAPGSWHLGSGEEKAFQFYNSCMDTDAIEASG 146

  Fly   132 LNTLQNVTDFRGGWPEIRVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKMHRLKIG 196
            ...|..:.:..|||.  ...:|...:::  |.:..|..:.|
Mouse   147 SGPLIQIIEELGGWN--ITGNWTSLDFN--QNLRLLMSQYG------------------------ 183

  Fly   197 APQFPMSRRHYLHPH---------------------FEGTREIYERSIE------NKLKLYFPEQ 234
              .||..|. ||.||                     .|..:::|.:.:.      |:|.......
Mouse   184 --HFPFFRA-YLRPHPAPPHTPIIQIDQPEFDILLQQEQEQKVYAQILREYVTYLNRLGTLLGSN 245

  Fly   235 SEHWRQEVASQVV-----------QIEQQLAKGLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVT 288
            .:..:|..:..:|           |.:||....|.|...:...|        ||..|    :|..
Mouse   246 PQEAQQHASWSIVFTSRLFQFLRPQQQQQAQDKLFHVVTIDELQ--------EMAPA----IDWL 298

  Fly   289 RYLQLIFND---NLYMDLYETPEDYMSNLVDVIRE---------------------TP----KLQ 325
            ..||.||..   |....|.....||:.|:..::.|                     :|    |.|
Mouse   299 SCLQAIFTPMSLNSSQTLVVHDLDYLRNMSQLVEEGLLNHRESIQSYMILGLVDTLSPALDTKFQ 363

  Fly   326 LANYTMWKALEAL-DIARVPASQRADIW--CVQLAQQFFPHQLESLFHRNYNHMQMINELQSTWS 387
            .|...:.:.|..| :...:||..|   |  ||:....||...|.:||.|......:.:.....::
Mouse   364 EARRELIQELRKLKERPPLPAYPR---WMKCVEQTGAFFEPTLAALFVREAFGPSIQSAAMELFA 425

  Fly   388 DIKRVFREDLQASERLLWLTLETRQKAITKLEALKLHF----RTHDDNKLIRQMHGLILNMDRFY 448
            :||...   :...::|.|::.||:::|:.||..|::..    |....:...::.:.:.|. ..|.
Mouse   426 EIKDAV---IIRLKKLSWISEETQKEALNKLAQLQVEMGAPKRAVKPDIATQEYNDIQLG-PSFL 486

  Fly   449 PNLVSVLQWKTQRGLAKLMTEPVAEDEVHKLP-----HYEIQKNRIQVPITFLQARFFWDPAYPN 508
            .:.:|.::....|.:...: :|.......|.|     :|.|..:.:..|...||..|| .|.||.
Mouse   487 QSFLSCVRSLRARNVQSFL-QPFPYHRWQKSPWEVNAYYSISDHMVVFPAGLLQPPFF-HPGYPR 549

  Fly   509 GLKYATLGVLLARQMLHGF-----DGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVE 568
            .:.:...|.::|.::||.|     .|.....|.         |..:.:    ..|.:..||.|..
Mouse   550 AVNFGAAGSIMAHELLHIFYQLLLPGGCPACDT---------HVLQEA----LLCLERHYAAFPL 601

  Fly   569 YKGKPVQDKDLLRRIVADNGALDIAYRAY-QQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYA 632
            ...........|....||.|.:.||::|| ::.:::..|.       .||.||....|:|:..||
Mouse   602 PSISSFNGSHTLLENAADIGGVAIAFQAYSKRIVEHTGEL-------TLPNLDLSPYQLFFRSYA 659

  Fly   633 QLYCTDYPETVERFDELPEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686
            |:.|........:....|..|||:..|||:..||..:.|.|...||...:|.|:
Mouse   660 QVMCRGLSSQDPQDPHSPPSLRVHGPLSNTPDFAKHFHCPRGTLLNPSARCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	57..684	CDD:189000	145/710 (20%)
		PepO	57..677	CDD:226118	143/703 (20%)
Kel	NP_115929.3	M13	78..711	CDD:341056	145/713 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841119
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.810