Protein Alignment Nepl15 and nep-24

DIOPT Version :9

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 618
• Identity: 131/618 - (21%)
• Similarity: 242/618 - (39%)
• Gaps: 131/618 - (21%)

  Fly     7 GLLLGAILFSIC----AIDASVPHPLAANYSIDILRLAKAAHIKAYMGDEKEQACNNFYNYACAN 67
            |.:|  :|...|    ||.|:.|   |.....:.......||:.....|.....|:||:.:||.
 Worm    12 GFML--LLLLTCTAPLAIGATTP---ATRNVCNTPACITLAHMLHNYHDPSVDPCDNFHQFACG- 70

  Fly    68 WPRLHP-------ARKSKTRTNYLEELQELYIRKSADMLKSATRGAENSADRQLKYFYGSCR-LQ 124
              |.|.       .:|:||..|.::.    :::|:     ..:|....:|.|.|   |.:|: |:
 Worm    71 --REHEHETEDIYTKKTKTINNIMKR----FLKKN-----ETSRSKSENAMRTL---YKACKTLE 121

  Fly   125 TNDTRSALNTLQNV-TDFR--GGWPEIRVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYK 186
            .|.|.|....||:: .|.:  |.||.:. ..|.:.::|....:.||.| ||...| ||..:..|
 Worm   122 KNSTASRNKALQDIFQDIQSIGAWPVVD-DKWDESKFDLNDFLVNLVR-LGRKNF-GLFQMARY- 182

  Fly   187 EEKMHRLKIGAPQFPMSRRHYLHPHFEGTREIYERSIENKLKLYFPEQSEHWRQEVASQVVQIEQ 251
             ..:....|| |:  .:.||.:......:..:...|::...|....:.:|:         |.:|:
 Worm   183 -VNVRNFAIG-PE--AAWRHNVDLGKTISEILKANSVQTNNKKLLDDLAEY---------VNLEK 234

  Fly   252 QLAKGLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTR-YLQLIFND------NLYMDLYETPED 309
            .|::   |.     ..|.:.......::.:.|.|:.:| .|:::..|      .:|..:|.|...
 Worm   235 ALSQ---HK-----FNTVQPGYIFSERSDFVSSVNFSRLVLEMMSPDKRTLFPEVYQIMYLTNTS 291

  Fly   310 YM----SNLVDVIRETPKLQLANYTMWKALEALDIARVPASQRADI-------WCVQLAQQFFPH 363
            ..    :||..:||.|.|..||||.::|.::         :..||:       :|.|....|.|.
 Worm   292 LFFGKNNNLETIIRNTSKRALANYLIFKFID---------TSIADLTYGSPSAFCEQKVINFLPR 347

  Fly   364 QLESLFHRNY----NHMQMINELQSTWSDIKRVFREDLQASERLLWLTLETRQKAITKLEALKLH 424
            .....|:||:    |..::....::|...:.::    :.|::   |:::::::.|:.::.::.:.
 Worm   348 AALRAFYRNFISKENRKKITKLTEATQVQLLKI----IGATD---WMSIKSKKIAMDRVSSMNMV 405

  Fly   425 FRTHDDNKLIRQMHGLI--LNM---DRFYPNLVSVLQWKTQRGLAKLMTEPVAEDEVHKLPHYEI 484
            ....|......::.||.  ||:   |.:|         ...|.:.:.|.|...:....::|:|.:
 Worm   406 IGYPDYFDPPGKLDGLFEHLNLSSSDTYY---------TVVRKINRFMREQEMDYYTGEVPYYPL 461

  Fly   485 ------------QKNRIQVPITFLQARFFWDPAYPNGLKYATLGVLLARQMLHGFDGVGRRYDAY 537
                        ..|.:.:...|....|| |.::|:....|.....||.:|.|.|.  ....|..
 Worm   462 FPGLMTNAMYNANDNNLMIFAPFFDDPFF-DSSFPDYANIAFTSNTLAHEMGHTFS--PHLMDIM 523

  Fly   538 -GYKNNWWDHTSESSYSRRTQCFQEQYAIFVEY 569
             |....|........|.:|.:|.::||   .||
 Worm   524 TGTTEVWLTPKETEEYEKRVKCLEDQY---TEY 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	57..684	CDD:189000	119/564 (21%)
		PepO	57..677	CDD:226118	119/564 (21%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	119/567 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920