Protein Alignment Nepl15 and nep-20

DIOPT Version :9

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001317749.1
• Gene: nep-20 / 188176
• WormBaseID: WBGene00020293
• Length: 834
• Species: Caenorhabditis elegans
• Alignment Length: 697
• Identity: 147/697 - (21%)
• Similarity: 273/697 - (39%)
• Gaps: 138/697 - (19%)

  Fly    42 AAHIKAYMGDEKEQACNNFYNYACANWPRLHPARKSKTRTNYLEELQELYIRKSADMLKSATRGA 106
            |..:.||. |.....|:|||...|..:.  |.....|.|....:|:.:..:|   :.|:......
 Worm   224 AFELSAYQ-DTSVSKCHNFYKATCGKYK--HHQALDKHRDAKKKEVVKRIVR---EFLRRNESSI 282

  Fly   107 ENSADRQLKYFYGSCRLQTNDTRSALNTLQNVTDFRGGWPEIRVASWYQYEYDWLQVVANLKRKL 171
            .:..:..::..:|.|. :.:..::.|:..:::... |.||.::        .||:.|:.||...|
 Worm   283 TSKFEPAIRLMFGKCN-KFSQNKTYLDIFKDIEKI-GPWPVLK--------SDWVDVMFNLNDYL 337

  Fly   172 GVDIFIGLEVILDYKEEKMHRLKIGAPQFPMSRRHYLHP--HFEGTR------EIYE----RSIE 224
            ...:.:|   ..|:...|:...::...|||:     :.|  ..:|.:      ||.|    ::..
 Worm   338 LSLVELG---FTDFGLFKLEFRQLAFGQFPV-----IAPSEQKQGNQLEKIILEILEANGVQADR 394

  Fly   225 NKLKLYFPEQSEHWRQEVASQV--VQIEQQLAKGLPHNPA-LTLAQTTRQRTAAEMKTAYGSYVD 286
            .||..|..|.|     |..||:  :.:|....|.:.:|.: |::..:...:..|.|.|:.|
 Worm   395 QKLSKYLREYS-----EFKSQLRHMSLEGTSVKYIRYNASTLSVNISALVQKMAPMSTSSG---- 450

  Fly   287 VTRYLQ---LIFNDNLYMDLYETPEDYMSNLVDVIRETPKLQLANYTMWKALEALDIARVPASQR 348
            :.|.:|   ||.|.:.:         :..||..:|::|.|..||||.::..::|:.......::.
 Worm   451 LVRRIQSGILITNSSSF---------FGKNLDAIIQQTHKRTLANYLIFHFIDAVTFDLTSGAKH 506

  Fly   349 ADIWCVQ---------LAQQFFPHQLESLFHRNYNHMQMINELQSTWSDIKRVFREDLQASERLL 404
            ::...:.         |:|.|...:.:.:.      ::|..:|:   ..:..:..|.....:..|
 Worm   507 SEHTLIDLLPRGSLQVLSQDFVDEEDQGVM------VEMAKDLK---KHVVEMISEGSSLDKGHL 562

  Fly   405 WLTLETRQKAITK-----------LEALKLHFR----THDDNKLIRQMHGLILNMDRF-YPNLVS 453
            ....:.|:|.|.|           ||.|..:|.    |:.|:     :|.:|..:.|| ...|:.
 Worm   563 VFEEKERRKLIRKVQDILVVTKYPLEILNQNFEKLNLTYSDS-----LHKIIQKLRRFRSEQLIE 622

  Fly   454 VLQW---KTQRGLAKLMTEPVAEDEVHKLPHYEIQKNRIQVPITFLQARFFWDPAYPNGLKYATL 515
            .|..   .|.:|:             ....|||...|.:.:....:...:| |.:|||.:....:
 Worm   623 YLGGDLDPTDKGM-------------WGSAHYEQATNDLIIIAPIIDGPYF-DTSYPNYVNIFFM 673

  Fly   516 GVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVEYKGKPVQDKDLL 580
            |.:::|::....|.|..|.|..|:..||....|...:....:|::           |.:.....|
 Worm   674 GFIISRELGRSLDSVRIRKDEKGHTENWLKSESLKRFDNNVKCWR-----------KKITGTRFL 727

  Fly   581 RRIVADNGALDIAYRAYQQWLKNAAETPV--IYQRERLPLLDHDHNQIFYLGYAQLYCT----DY 639
            ..::||:...:.::.|.::|.|....|.|  |...|.:.:     .|||:...|..:|.    ..
 Worm   728 NEMLADHVGHEASFMALKKWEKEMNGTIVEKIRGYESMTM-----EQIFFHLQALYFCRPPGGST 787

  Fly   640 PETVERFDELPEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686
            .|...:........|||.|..|..|||.|:|||..:.:|::.|||.:
 Worm   788 GELTAKDARQHYSTRVNEAFKNMPQFAKAFGCSSNQNMNSKTKCTFF 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	57..684	CDD:189000	141/678 (21%)
		PepO	57..677	CDD:226118	139/671 (21%)
nep-20	NP_001317749.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920