Protein Alignment Nepl15 and nep-10

DIOPT Version :9

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_494532.2
• Gene: nep-10 / 173684
• WormBaseID: WBGene00017555
• Length: 711
• Species: Caenorhabditis elegans
• Alignment Length: 722
• Identity: 152/722 - (21%)
• Similarity: 276/722 - (38%)
• Gaps: 137/722 - (18%)

  Fly    23 SVPHPLAANYSIDILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLHPA---RKSKTRTNYL 84
            :|..|.....|.:.:.||...|   ...|.....|.:||.:.|..:.. |.|   .:..|:.:.|
 Worm    69 TVDEPRNVCESPECITLAHELH---NYKDPSVDPCQDFYQHFCGKFYE-HSAIGQGRMATKRSTL 129

  Fly    85 EELQELYIRKSADMLKSATRGAENSADRQLKYFYGSCRLQTNDTRSALNTLQNVTDFRGGWPEI- 148
            .:|...::.|:    |::|..:||:    :|..|..||           .||.::|.....|:.
 Worm   130 SKLIREFLLKN----KTSTSKSENT----MKQVYAKCR-----------ELQKISDLNSIPPQAL 175

  Fly   149 --------RVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKMHRLKIGAPQFPMSRR 205
                    ::.:|...:.||.....||...|...:.:|          :.|   :|...|....|
 Worm   176 LDIFSDIKKIGAWPVLDKDWDGSKFNLNEMLRQLVNLG----------ETH---LGFFHFDFIAR 227

  Fly   206 HYL---HPHFEGT-REIYERSIE-----NKLKL--YFPEQSEHWRQEVASQVVQIEQQLAKGLPH 259
            .|:   .|..:|. :.:.|:.::     |::|:  .|.|..:.:.:  .|..::|::     ||.
 Worm   228 PYVLIKPPLKQGVQKSVLEKVVKMILEANEIKMDQGFSEDLDEYFE--LSNRIKIDK-----LPR 285

  Fly   260 NP----------------ALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFNDNLYMDLYETPE 308
            ..                .|.|....|.:....:.|.:...  ||.:..|...||      ||
 Worm   286 TSRSIVGLLPDVRRINFRGLILEMMPRSKMNRFLGTLFQKV--VTYHHPLFVRDN------ET-- 340

  Fly   309 DYMSNLVDVIRETPKLQLANYTMW----KALEALDIARVPASQRADIWCVQLAQQFFPHQLESLF 369
               ::|..:||.|....||||.::    .:::.|........:|    |.::..|..|.....:|
 Worm   341 ---NHLDTIIRSTSNRALANYLIFNFIHSSIKFLTFGLKSDRER----CEKIVVQELPRPSLRVF 398

  Fly   370 HRNYNHMQMINELQSTWSDIKRVFREDLQASERLLWLTLETRQKAITKLEALK--LHFRTHDD-- 430
            .||........|:......:|....|.::.|:.   .|...:::.:.|:||:.  :.:..|.|
 Worm   399 MRNCVDKGNREEVAKLTETVKENVLEMIRESDS---FTPSVKKRVLKKVEAIGAIIGYPDHFDPP 460

  Fly   431 NKLIRQMHGLILN-MDRFYPNLVSVLQWKTQRGLAKLMTE-PVA-EDEVHKL-PHYEIQKNRIQV 491
            ..|.::...|.|: .|.:|.....:.|.:.|..:..|..: |:: .|:|.:: .||:.:.|.:.|
 Worm   461 GTLDKEYENLTLDASDSYYKMSQKLHQLRLQHQMEFLAGQTPLSPSDQVLEVNAHYDSKDNALTV 525

  Fly   492 PITFLQARFFWDPAYPNGLKYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRT 556
            ...||...|| |..||..:.....|.|:..:..|..|....|.|      .|:.....:.|.:|.
 Worm   526 LAPFLDDPFF-DSTYPEYVNLIFTGFLIGHEFGHSIDPKILRRD------GWYKTEDMTEYGKRA 583

  Fly   557 QCFQEQYAIFVE-YKGKPVQDKDLLRRIVADNGALDIAYRAYQQWLKNAAETPVIYQRERLPLLD 620
            ||..:||..:.: ..||.:.....:..||.|....|:.:||:::...:..:..:.::.:.|..|.
 Worm   584 QCLIDQYDNYDDPDHGKQMNGTYCIGEIVGDWVGRDVTWRAFKKMDLSKMQKLIGFEDKNLDQLY 648

  Fly   621 HDHNQIFYLGYAQLYCTDYPETVERFDEL------PEQLRVNTALSNSQQFANAYGCSREEKLNA 679
            .....:|:.|         |.:::..::|      .|..|||...||..|||.|:.|.....:|.
 Worm   649 FRIQSLFFCG---------PRSMKSLEQLLSDPHPTEVFRVNGIYSNMPQFAKAFNCPIGSPMNP 704

  Fly   680 RFKCTLY 686
            ..||.::
 Worm   705 EKKCKMF 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	57..684	CDD:189000	144/684 (21%)
		PepO	57..677	CDD:226118	142/677 (21%)
nep-10	NP_494532.2	M13	97..709	CDD:189000	144/687 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920