Protein Alignment Nepl15 and Nep2

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_061497288.1
• Gene: Nep2 / 1281326
• VectorBaseID: AGAMI1_002834
• Length: 792
• Species: Anopheles gambiae
• Alignment Length: 696
• Identity: 168/696 - (24%)
• Similarity: 282/696 - (40%)
• Gaps: 91/696 - (13%)

  Fly    51 DEKEQACNNFYNYACANWPRLHPARKSKTRTNYLEELQELYIRKSADMLKSATRGAENSADRQLK 115
            |::.:.|::||||||..:.:.......|...|....:.:...::...::......:|.:..:..|
Mosquito   128 DQEVEPCDDFYNYACGKFVKETVIPDEKVSVNTFSVIGDRLQQQLRSLVSEEISDSEATPFKLAK 192

  Fly   116 YFYGSCRLQTNDTRSALNTLQNVTDFRGGWPEIRVASW-YQYEYDWLQVVANLKRK-LGVDIFIG 178
            ..|..|..:|......:..|.::.:..||||.::..|| ....:.|::.|.:.:.. ...|.|..
Mosquito   193 NLYKLCMNKTRIEEKGIKPLLDIHEVLGGWPVLKGDSWDLDSSWSWVKSVKDFRNNGYSTDYFFD 257

  Fly   179 LEVILDYKEEKMHRLKIGAPQFPMSRRHYLHPHFEG--TREIYERSIENKLKLYFPEQSEHWRQE 241
            ..:..|.|......:........:| |.||....|.  ....|...::..:.|...|  |..::|
Mosquito   258 FSIGSDLKNSTRRIIDTDQASLGIS-REYLVKGMENPIVSAYYNYMVDMAVLLGADE--ERAKRE 319

  Fly   242 VASQVVQIEQQLAK-GLPHNPALTLAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFND------NL 299
            :... :..|..||. .||:.............|..|.:..| .|.|...|...|..|      ..
Mosquito   320 LLDS-LNFEMALANISLPNEKRRNATALYNPMTVKEFQQRY-PYTDWLEYFNAILKDTGIVIGEE 382

  Fly   300 YMDLYETPEDYMSNLVDVIRETPKLQLANYTMWK--------ALEALDIARVPAS-------QRA 349
            .:.:...| .:|..|..:::.|||..:|||.||:        ..|.|...::..|       ::.
Mosquito   383 EVIIVSVP-TFMEQLGPLLQNTPKRVMANYVMWRISGFSSFFLTEKLRKRQLQYSTALSGKQEQE 446

  Fly   350 DIW--CVQLAQQFFPHQLESLFHRNYNH-------MQMINELQSTWSDIKRVFREDLQASERLLW 405
            ..|  ||.:.....|..:.:|:.|.|..       :.|:|:::|.:.||.:          ::.|
Mosquito   447 PRWKECVDITSGSLPISVGALYIRKYFREDSKRAALDMVNDIKSVFVDILK----------KVDW 501

  Fly   406 LTLETRQKAITKLEALKLHF----RTHDDNKLIRQMHGLILNMDRFYPNLVSVL-QWKTQRGLAK 465
            :...||..|:.|:..:..|.    ...||.|:......|....|..|.|.:..: ::.|.:...|
Mosquito   502 MDEVTRVSALEKVSTMATHIGYPDELMDDAKIAEYYKDLEFQPDSTYLNTILYMNKFGTTKAFKK 566

  Fly   466 LMTEPVAEDEV-HKLP-----HYEIQKNRIQVPITFLQARFF-WD-PAYPNGLKYATLGVLLARQ 522
            |.......|.: |..|     .|...:|.||.|...||.:|| :| |.|.|   |..:|.::..:
Mosquito   567 LRIAVNKTDWITHSRPAIVNAFYSSIENSIQFPAGILQGQFFSYDRPKYMN---YGAIGFVIGHE 628

  Fly   523 MLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVE------YKGKPVQDKDLLR 581
            :.||||..||::|..|...:||...::::|..:.:|..|||..:.|      ..|...|.::
Mosquito   629 ITHGFDDQGRQFDKNGNLVDWWQSDTKTAYLEKARCIIEQYGNYTEPNVKLNLNGINTQGEN--- 690

  Fly   582 RIVADNGALDIAYRAYQQWL-KNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYCTDY-PETVE 644
              :||||.:..||.||::|. ||..|       :|||.|:....|:|:|..||.:|:.| |||::
Mosquito   691 --IADNGGIKEAYYAYRRWTEKNGPE-------QRLPGLNLSPEQMFWLSAAQTWCSVYRPETMK 746

  Fly   645 -RFD---ELPEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686
             |..   ..|.|.||...:||..:||..:.|.....:|...||.::
Mosquito   747 MRITTGVHSPGQFRVLGPMSNMHEFAKDFNCPVGSPMNPEHKCEVW 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	166/687 (24%)
Nep2	XP_061497288.1	None