Protein Alignment Nepl15 and Nep4

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_061501026.1
• Gene: Nep4 / 1273777
• VectorBaseID: AGAMI1_013990
• Length: 1007
• Species: Anopheles gambiae
• Alignment Length: 817
• Identity: 199/817 - (24%)
• Similarity: 321/817 - (39%)
• Gaps: 213/817 - (26%)

  Fly    33 SIDILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLHPARKSKTRTNYLEELQELY------ 91
            |.:.:|.|:.|.:|.|| |.....|::||.|||.||.|::|..|.|...:..|.|:|..
Mosquito   241 SPESVRAAQVAIMKQYM-DPDADPCDDFYQYACGNWDRVNPIPKDKAALDTFELLRESLDLVLKQ 304

  Fly    92 -------------------IRKSADMLKSAT------------------------------RG-A 106
                               :|...|..|.:|                              || |
Mosquito   305 LLLEGEPAGLLDVENALSTVRSQPDGTKKSTSTTTTAASAGWPTTTVTGGPAQQQLHRVRKRGRA 369

  Fly   107 EN--------------------------------SADRQLKYFYGSCRLQTNDTRSALNTLQNVT 139
            ||                                .|:.:.::.:.||.......|..|..|:.:.
Mosquito   370 ENRNRSGRAVQNKLIIRSAQVKRVRRKRELLINDDAEMKARHLFVSCMNYELIERRGLEPLRTLL 434

  Fly   140 DFRGGWPEIRVASWYQYEYDWLQVVANLKRK---------LGVDIFIGLEVILDYKEEKMHRLKI 195
            ...||||.:...:|.:..:|||.:.|.|:|.         :|.||....|.|:.:.:     ..:
Mosquito   435 HSLGGWPVLEPHTWDESSFDWLNLTAALRRYNNDVLIVEWVGPDIKNSDENIVQFDQ-----TSL 494

  Fly   196 GAPQFPMSRRHYLHPHFEGTREIYERSIENKLK----LYFPEQSEHWRQEVASQVVQIEQQLAKG 256
            |.|    :|.:||.|   |.|:..|...:..|:    |..|..:   .::...::::.|.|||
Mosquito   495 GLP----TRDYYLQP---GNRKYLEAYRQFMLEVIGLLDVPADT---ARQATDEMIEFETQLA-- 547

  Fly   257 LPHNPALTLAQTTRQRTAAEMKTAYGS-----------YVDVTRYLQLI----FNDNLYMDLYET 306
                   .:..|..:|.  .:.|.|..           .::.|.||.::    .|.:.::.::..
Mosquito   548 -------NITSTPEERN--NVSTLYRKLMLDQLQEEVPQINWTHYLTIVTERPVNGSSFVVMFAM 603

  Fly   307 PEDYMSNLVDVIRETPKLQLANYTMWK----ALEALDIARVPASQR-----------ADIW--CV 354
              .||.:||::|.:|....:|||.:|:    .:..||...:.|.||           ...|  ||
Mosquito   604 --SYMRDLVELIDQTEPRIVANYLLWRFVRHRINNLDDRFLGAKQRFSNALFGRERNPPRWKNCV 666

  Fly   355 QLAQQFFPHQLESLFHRNY-------NHMQMINELQSTWSDIKRVFREDLQASERLLWLTLETRQ 412
            ..........:.::|.|.|       :.:.|.:|||.       .|||.|   .|..|:.:.|||
Mosquito   667 TQVNANMGMAVGAMFVRRYFDENSKRDTLTMTHELQD-------AFREIL---GRTGWIDMATRQ 721

  Fly   413 KAITKLEALKLHFR----THDDNKLIRQMHGLILNMDRFYPNLVSVLQWKTQRGLAKLMTEPVAE 473
            .|..|:.|:.|...    ..|..:|..:...|.::.||::.|.::||....:....|| .:||.:
Mosquito   722 LAEQKVNAMSLRIGYPDFILDPEQLSARYATLEIHPDRYFENTLNVLSHIRRTDQEKL-GQPVNK 785

  Fly   474 DEVHKLP-----HYEIQKNRIQVPITFLQARFFWDPAYPNGLKYATLGVLLARQMLHGFDGVGRR 533
            ...|..|     :|...||:|..|...||..|: ....|..:.|..:||::..::.||||..||.
Mosquito   786 TAWHTAPAVVNAYYSRNKNQIMFPAGILQPPFY-HRHLPKAINYGGIGVVIGHELTHGFDDKGRL 849

  Fly   534 YDAYGYKNNWWDHTSESSYSRRTQCFQEQYA------IFVEYKGKPVQDKDLLRRIVADNGALDI 592
            :|..|....||...:...:..|..|..|||.      :.|:..|:..|.::     :||||.:..
Mosquito   850 FDRDGNLYRWWSDRAIEEFHERAACLVEQYGRYRIAEVDVQLDGENTQGEN-----IADNGGIKQ 909

  Fly   593 AYRAYQQWLKNAAETP-VIYQRERLPLLDHDHNQIFYLGYAQLYC-TDYPETVERFDEL------ 649
            |:.||.:||  ||:|. .:.:.|.||.|:....|:|:|.:||::| ...||...  ::|
Mosquito   910 AFLAYSKWL--AAQTDRRVLEAETLPGLNVTRTQLFFLNFAQIWCGAMRPEATR--NKLKTAVHS 970

  Fly   650 PEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686
            |.:.||...||||:.||..|.|.....:|...||:::
Mosquito   971 PGRFRVIGTLSNSEDFAREYHCPVGSTMNPPGKCSVW 1007

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	190/790 (24%)
Nep4	XP_061501026.1	None