Protein Alignment Nepl15 and mme

DIOPT Version :10

• Sequence 1: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_031758820.1
• Gene: mme / 101734885
• XenbaseID: XB-GENE-1011098
• Length: 746
• Species: Xenopus tropicalis
• Alignment Length: 779
• Identity: 183/779 - (23%)
• Similarity: 326/779 - (41%)
• Gaps: 148/779 - (18%)

  Fly     5 PL--GLLLGAILFSICAIDASVPHPLAANYSIDILR--LAKAAHIKAYMGDEKEQACNNFYNYAC 65
            ||  ||::..|...|.:| |.:.....:|..|...:  ::.||.|.|.| |.....||:||.|||
 Frog    19 PLEKGLIILCIFLGIISI-AMILAYATSNDGICTSQACISTAARIIANM-DAATDPCNDFYQYAC 81

  Fly    66 ANWPRLHPARKSKTRTNYLEELQELYIRKSAD-MLKSATRGAENSAD-----RQLKYFYGSCRLQ 124
            ..|     .:|::...|.:.......:|...: :||.|..  :.|||     :::|.||.||..:
 Frog    82 GGW-----LKKNRIPDNNIVSNTFDILRTDIEVVLKDALE--KESADDIPAIKKVKTFYKSCIDE 139

  Fly   125 T-NDTRSA---LNTLQNVTDFRGGWPEIRVASW-YQYEYDW--LQVVANLKRKLGVDIFIGLEVI 182
            | .:.|..   :.||..:.|    || |.|.:| .:|...|  .:.:|....|.|....|.:.|.
 Frog   140 TIKNLRKGGPLIKTLPALYD----WP-IAVDNWETRYGLVWSAQESIAGFITKYGQSGLINVYVS 199

  Fly   183 LDYKEEKMHRLKIGAPQFPMSRRHYLHPHFEGTREI----YERSIENKLKLYFPEQSEHWRQE-V 242
            .|......:.|.|..|...:..:.|.  ..:||.||    |...:.:...|...|::....:: :
 Frog   200 EDLTNSSTYILHIDQPGLGLPSKDYY--DCKGTSEIACLAYMEQMVSVAMLIRKERNLTINEDKI 262

  Fly   243 ASQ---VVQIEQQLAKG-----LPHNPALTLAQTTRQRTAAEMKTAY------------------ 281
            .|:   |.::|:::||.     :..|    |....::.|.:.:...|
 Frog   263 LSEMEKVFKLEREIAKAEASEEIREN----LNDIYKKMTLSGIAKTYPLKMNDQNINWLKLINAI 323

  Fly   282 ----GSYVDVTRYLQLIFNDNL----YMDLYETPEDYMSNLVDVIRETPKLQLANYTMWK-ALEA 337
                |..::....:.||.:|.|    :::.|:..|                 |.||..|: .|.|
 Frog   324 ISPGGVSIEENEQVALICSDYLKKLRFLNKYKARE-----------------LQNYLGWRYILSA 371

  Fly   338 LDIARVP---------------ASQRADIWCVQLAQQFFPHQLESLFHRNY---------NHMQM 378
            ::...:.               |::.:| |  |....:....:|....|.|         .|:::
 Frog   372 INDLSLEYKNTGIHLKKALYGNAAEGSD-W--QTCVTYLNDNMEDAIGRLYLKETLSADIEHVKV 433

  Fly   379 INELQSTWSDIKRVFREDLQASERLLWLTLETRQKAITKLEAL--KLHFRTH--DDNKLIRQMHG 439
            .::::...::|:|.|.|.|   |.:.|:..:|:::|..|:.::  ::.|...  ||.||......
 Frog   434 KDKVKEIIAEIRRAFLEML---EEMDWMDEDTKKRAARKVASINERIAFSEDIMDDFKLNEGYSE 495

  Fly   440 LILNMDRFYPNLVSVLQWKTQRGLAKLMTEPVAEDE-----VHKLPHYEIQKNRIQVPITFLQAR 499
            |...:|..:.|....::: .|:.:...:.:.|.::|     .|....|.:..|.|..|...||..
 Frog   496 LEFRVDELFENKQKYIEF-VQKKMTSRLRKQVNKNEWVPGPAHVNAFYSLTYNEIVFPAGILQTP 559

  Fly   500 FFWDPAYPNGLKYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYA 564
            || ..:.|:.|.|..:|:::..::.||||..|..:|.:|...|||.:.|..::|..:|||..||.
 Frog   560 FF-SSSQPSALNYGGIGMIIGHEITHGFDNRGCNFDEHGNLVNWWTNASMMNFSNLSQCFVNQYG 623

  Fly   565 IFV--EYKGKPVQDKDLLRRIVADNGALDIAYRAYQQWLKNAAETPVIYQRERLPLLDHDHNQIF 627
            .:.  |..|:.:.....|...::|||.:..||||::.::|:..|.      :.||.:|.|.:|:|
 Frog   624 NYSWDEAGGQYLNGISTLGENISDNGGIRGAYRAFKNYVKSHKED------DLLPGIDLDSDQLF 682

  Fly   628 YLGYAQLYC----TDYPET-VERFDELPEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY 686
            ::.:.|::|    .:|..| ::.....|...||...|.||.:|:.|:.|.....:|...||.|:
 Frog   683 FISFGQIWCGMHRPEYAATLIKTGSHTPGIFRVIGTLQNSPEFSKAFSCCNNAYMNPAVKCKLW 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl15	NP_651098.2	M13	56..684	CDD:341056	165/720 (23%)
mme	XP_031758820.1	M13	71..744	CDD:341056	165/721 (23%)