Protein Alignment Nepl14 and Nepl21

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Alignment Length: 718
• Identity: 190/718 - (26%)
• Similarity: 331/718 - (46%)
• Gaps: 83/718 - (11%)

  Fly    23 ALVSGEDL--PPPFQRIYQSEQTVRRSKAQDMGSHVNKSIDPCVDFYAYACGNWK---STLTPQ- 81
            |..|.|||  ..|:.:     :.:|::|..::.|.:::..|||.||||::|||:|   |.|:.|
  Fly    29 APTSEEDLKQDTPYMK-----ELLRQAKTAEIESFMDQKADPCNDFYAFSCGNYKRINSALSMQV 88

  Fly    82 ------QQLQQQTDRELLLLVEEAVRREDSVIVRQAKELFKSCVSAQ---AHQSQQQQHFLSEFI 137
                  :.|.:..:|::|.::.......|:....:.|..::||:..:   :..|::.:..::||
  Fly    89 VTTGVFETLTKGLNRKILKMLNTPHDSHDTPEDIKVKHFYESCLQIKELNSTYSEKLKRLIAEF- 152

  Fly   138 NQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYGMDILIGLRVGYNYGNVNENSLYLSEPSTLI 202
               |..|.:.||.|  ...|::||:....:..|||:..:.|:.|..:..:...|.:||.:..  .
  Fly   153 ---GTMPLLEGSSW--QEDDFDWLNTTARMAYRYGITPIFGIEVNKDLASNTRNRIYLGQQD--F 210

  Fly   203 PTELCTRNRSDIRDSIYEPLEHRVASELKSWLALGHDESARLAADILSFEHELCGGMKGGSFESW 267
            |.|..:....|......:...:.:...|:.:|.:..|.:.:.|.:::.||.:|..|:.
  Fly   211 PLEARSMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKELIDFEVDLAQGLV------- 268

  Fly   268 DAEEQLYLANYTR-KTLREFSN--SIELDLDSYVRASFGQDIYKPVYMAAPEYFRQLKRTVSAHN 329
            |..|.|.:...|: .|:.|...  |..||:|..:..|.|:.|...:|.....|.:.|...:....
  Fly   269 DESEGLDVGELTQLLTVDEIQRRYSPTLDIDRLLFVSMGERISDQIYEYNNRYQQNLVEVIKRTP 333

  Fly   330 ISLVANYIMYRAVSALNFPLDDRPQLRKRECLERTKELLPTALGELYARQFGTEDGRIDLDNLYD 394
            ...|||||.:|.:........|.|:.:.:.|::.||:.....|..::.|::..|....::||::.
  Fly   334 KRTVANYIFFRLIWEFVETPSDSPEKQMKACVDLTKKYFAKNLDNMFYRRYNNEKSSREIDNMWR 398

  Fly   395 TLKT----ALRQSLGAEWLVEGTQRVGQEKLRNLKLQMPTYE----RPVILKLQLERGNYWQNLR 451
            .||:    .||.|....|:...|:.:...||:.:.|::..|.    .....:|.|:..:|.:|:|
  Fly   399 QLKSTFNETLRSSPALNWIERPTRNLAMAKLQAMTLEVNNYADDNFTEEFAELNLQSDDYVENVR 463

  Fly   452 --QLLGVVQSQRNNRLFEEFLPAPTDPVEAYEARVRLRP----VQRRLDMGLALLQP-PAYDPRY 509
              .|||..|       ..|.|..|..|.|| .:::...|    ::..:.:.:||||| ..:...|
  Fly   464 YTSLLGAKQ-------MREMLHKPAKPFEA-GSQLSYTPANILIENTIKVPVALLQPFYIWSDVY 520

  Fly   510 GHAIRYATLGVQLAQQLVMAFDDPHWSVGLLERDN----WDGQTAWQYHIRSNCFARQVDNYLRP 570
            .:||.:.||...:..:|:..|||......  |:.|    ||.:::..:..|.:||.:|...|:..
  Fly   521 PNAIMFGTLASLIGHELIHGFDDSGRKFD--EKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYD 583

  Fly   571 NV-----SATTQLITDSAAINVAFRAYLTWLGFQ--EPNNDFTKLTKETLPDLNYSNTALFFLAY 628
            .:     :|.::.|.|:..:.:|:.||..|...|  .||. ...:||||||:|.|:...|||:::
  Fly   584 GIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNG-AQDMTKETLPNLRYTAKQLFFISF 647

  Fly   629 AQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNPASKC 693
            ||..|:  :|.|..:.      |..:...|...|..|.|.|.|..||:.||.||.||.|||:.||
  Fly   648 AQSWCN--DAHPSVKA------LQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKC 704

  Fly   694 IIY 696
            |:|
  Fly   705 ILY 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	177/674 (26%)
Nepl21	NP_651646.2	M13	63..704	CDD:341056	177/674 (26%)