Protein Alignment Nepl14 and Nepl6

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 743
• Identity: 159/743 - (21%)
• Similarity: 273/743 - (36%)
• Gaps: 222/743 - (29%)

  Fly    54 SHVNKSIDPCVDFYAYACGNW--KSTLTPQQQLQQQTDRE----LLLLVEEAVRR-------EDS 105
            |:|.:....|..::.||||.:  :....|..::.|..|.:    |:.|:.|..:|       |.|
  Fly    35 SYVAEDSSACGTYFQYACGKYAVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESS 99

  Fly   106 VIVRQAKEL--FKSCVSAQAHQSQQQQHFL-----------SEFINQNGGFPAVPGSQWAVHHHD 157
            |   :||.|  :::|..|.. .:::.:|:|           .:|:.:...:|..          .
  Fly   100 V---EAKVLHFYRTCREAPP-STRKMEHYLRLAPPGQALTWPQFMPRGEPWPKA----------Q 150

  Fly   158 YNWLSVLGGLRLRYGM-DILIGLRVGYNYGNVNENSLYLSEPS----------------TL---- 201
            :.|:..||.| .|||. ::|:.:.|..:..|.|...|.:|.||                ||
  Fly   151 FKWMKSLGHL-YRYGFTNVLVNVLVLRSSENSNRFRLDISMPSLEGDAQHLGGFLSTLATLQIIG 214

  Fly   202 IPTELCTRNRSDIRDSIYEPLEHRVASELKSWLALGHDESARLAADILSFEHELCGGMKGGSFES 266
            :||:........||         |:.|.::....:..|:.:                      |:
  Fly   215 VPTKSILPLVRKIR---------RLESAIRVLTEVDDDDES----------------------ET 248

  Fly   267 WDAEEQLYLANYTRKTLREFSNSIELDLDSYVRASFGQDIYKPVYMAA--PEYFRQLKRTVSAHN 329
            |              |||::..........:|.:..|..:.....|.|  .:||..|||.:.:.:
  Fly   249 W--------------TLRQWEYKTGYAWQGFVESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTD 299

  Fly   330 ISLVANYIMYRAVSALNFPLDDRPQLRKR-ECLERTKELLPTALGELYARQFGTEDGRIDLDNL- 392
            ..:||||||.|.|..|   :||.....:. :|:...:..:..|...||..:|      :|...|
  Fly   300 AEVVANYIMTRFVLYL---IDDFIDSNEHIDCVTDMRRNMNLASNLLYKERF------LDPATLQ 355

  Fly   393 -YDTLKTALRQSLGAEWLVE-GTQRVGQEKLRNLKLQMPTYERPVILKL-QLERG--------NY 446
             |....|.:.:.|..::|:: ...|:|....:|  ..:.|..:.|:|.: .|.||        .:
  Fly   356 QYTQEVTKVFEQLRRQFLLQINENRLGLTSEQN--SMVATKAQHVVLNIGNLPRGRDHRSFVSRH 418

  Fly   447 WQNL----------RQLLGVVQSQRNNRLFEEFLPAPT--------DPVEA------YEARVRLR 487
            :::|          |:.|.:::.:...::.:....|||        ||..|      |..|:.:.
  Fly   419 YEDLVFPLPDFDYAREHLNLLEFRTRKQVLQLNQSAPTPDEFFYLSDPKTAMSSGPYYLMRLNII 483

  Fly   488 PVQRRLDMGLALLQPPAYDPRYGHAIRYATLGVQLAQQLVMAFDDPHWSVGLLERDNWDG----- 547
            .|..      .|||.|.:........:|:.||..||.:|:.:.|    :|||. .|.:..
  Fly   484 VVPH------GLLQEPFFAADSHDIFKYSLLGFVLAHELMHSVD----TVGLY-YDRYGNIHEIG 537

  Fly   548 ---QTAWQYHIRSNCFARQVDNYLRPNVSATTQLITDSAAINVAFRAYLTWLGFQEPN----NDF 605
               .::.::.....|..|....||       .:.|.|.|.:::|:..|     ||..:    .||
  Fly   538 PQISSSPRFVAGLQCLNRNSTQYL-------DERIADIAGLDLAYSTY-----FQNSSQMSLTDF 590

  Fly   606 TKLTKETLPDLNYSNTALFFLAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRL--LVNGP 668
            |     |:|.     ..:|||..||..|.         .|.|..::   ..::..|||  ::||
  Fly   591 T-----TIPP-----QQIFFLNLAQFFCG---------DGDPINFV---GHDNDETRLQQMLNG- 632

  Fly   669 LRNSVEFASEFRCPIGSPMNPASKCIIY 696
               ...|...|.||..|  |...||.::
  Fly   633 ---FAPFHEAFGCPAKS--NQPEKCQLW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	155/732 (21%)
Nepl6	NP_609023.3	M13	47..653	CDD:341056	155/727 (21%)