Protein Alignment Nepl14 and Nepl5

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 755
• Identity: 171/755 - (22%)
• Similarity: 290/755 - (38%)
• Gaps: 180/755 - (23%)

  Fly    32 PPFQRIYQSEQTVRRSKAQDMGSHVNKSIDPCVDFYAYACGNWKSTLTPQQQLQQQTDREL---- 92
            |...|...:.|:|:...|:.:.|:::....||.:||.||||||        |:|||....|
  Fly    20 PTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNW--------QIQQQEQHSLRDRD 76

  Fly    93 -----------------LLLVEEAVRRE---------------DSVIVRQAKELFKSCVSAQAHQ 125
                             |.|::.:|.|:               ||.|:.|.:..::||...:.:.
  Fly    77 WTRDRQRYQGQMLPTDTLGLIDHSVNRKLELLLRRRNESSFESDSSILEQMRLYYRSCKRLKPYN 141

  Fly   126 SQQQQHFLSEFINQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYGMD-ILIGLRVGYNYGNVN 189
            .::....|..  :.:..:|:| |..|.....|  |::.||.||| :|:: :|:...|...:.:..
  Fly   142 LKKYLQLLPP--SNSTQWPSV-GRGWRPERFD--WITTLGRLRL-HGLNGVLLREEVLPRWDDSR 200

  Fly   190 ENSLYLSEPSTLIPTELCTRNRSDIRDSIYEPLEHRVASELKSWLALGHDE--SARLAADILSFE 252
            ..|:|:::||           |.:.     :|:......||  .|.:|..:  :..||..:..||
  Fly   201 NYSIYVNKPS-----------RQET-----QPMGEGAMIEL--LLDIGQTKRTANALARQVDDFE 247

  Fly   253 HELCGGMKGGSFESWDAEEQL-YLANYTRKTLREFSNSIELDLDSYVRASFGQDIYKPVYMAAPE 316
            .:| ..::....:....|.|| ||.:|..: ||..|...::.:||.:      |:...:.:....
  Fly   248 RKL-HRLQELEDDEGPREMQLGYLDSYLPQ-LRWLSFMRQVRIDSEL------DLRSTLIIENIP 304

  Fly   317 YFRQLKRTVSAHNISLVANYIMYRAVSAL--NFPLDDRPQLRKRECLERTKELLPTALGELYARQ 379
            |.|.|...:.:.:...|.:|||.:.::.|  ..|.|    :.:.||:...:..:|.|...|..:|
  Fly   305 YLRALSDLMESESPDTVCSYIMLKWLAFLKQQGPAD----ISRGECVAALRRAMPLASSWLVGQQ 365

  Fly   380 FGTEDGRIDLDNLYDTLKTALRQSLGAEWLVEGTQRVG-------QEKLRNLKLQMPTYERPVI- 436
            |...:....:.:|:..||....|.     |.|...|:.       |:|||.::|||..::...|
  Fly   366 FSDPESESYVSSLFQRLKVRFGQI-----LAENRMRLSPPLVHILQQKLRAVRLQMGFFQTEEIE 425

  Fly   437 ------LKLQLERGNYWQN----LRQ------------LLGVVQSQRNN--RLFEEFLPAPTDPV 477
                  :::.|...:::.|    |||            :.....|..:|  .|.|.:..:.:.|:
  Fly   426 DVEQYHVRIDLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEASNSSPL 490

  Fly   478 EAYEARVRLRPVQRRLDMGLALLQPPAYDPRYGHAIRYATLGVQLAQQLVMAFDDPHWSVGLLER 542
            ......:.|.|        ..|||.|.:........::|.:|..||.:|...||       :|..
  Fly   491 YVRPRNLVLVP--------HGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFD-------MLGM 540

  Fly   543 DNWDGQTAWQYHIRSNCFA-----------RQVDNYLRPNVSATTQLITDSAAINVAFR-AYLTW 595
            |         |....|...           ||....|:..::..::.|.:..|..||.| ||.|:
  Fly   541 D---------YDAMGNIMGPVEEIGASRQFRQGLQCLQQQMATGSKWIDEKLADFVALRLAYETF 596

  Fly   596 LGF---QEPNNDFTKLTKETLPDLNYSNTALFFLAYAQEHCSLEEA-RPRDEQGTPEGYLYSARQ 656
            .|.   :||.:..       ||  .:|...|||:.:||..|..... .||.:.        .|..
  Fly   597 FGVRDKREPRDPL-------LP--QFSQRQLFFITFAQFFCGRTPVLSPRSQS--------EAHL 644

  Fly   657 NHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNPASKCIIY 696
            .|....|.|...|.|..||:.||.|...:.|..:.:|.|:
  Fly   645 KHAADELRVMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	163/722 (23%)
Nepl5	NP_609022.1	M13	48..682	CDD:341056	163/723 (23%)